Reference health

Distinct mechanisms for TMPRSS2 expression explain organ-specific inhibition of SARS-CoV-2 infection by enzalutamide

https://doi.org/10.1038/s41467-021-21171-x
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Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

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The 49 checked references that resolve
resolves10.1016/j.cell.2020.05.041
Pandemic Preparedness: Developing Vaccines and Therapeutic Antibodies For COVID-19
resolves10.1038/s41586-020-2271-3
Aerodynamic analysis of SARS-CoV-2 in two Wuhan hospitals
resolves10.1128/JVI.02232-10
Evidence that TMPRSS2 Activates the Severe Acute Respiratory Syndrome Coronavirus Spike Protein for Membrane Fusion and Reduces Viral Control by the Humoral Immune Response
resolves10.1016/j.cell.2020.02.052
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
resolves10.1128/JVI.01542-10
Efficient Activation of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein by the Transmembrane Protease TMPRSS2
resolves10.1128/JVI.02062-10
A Transmembrane Serine Protease Is Linked to the Severe Acute Respiratory Syndrome Coronavirus Receptor and Activates Virus Entry
resolves10.1126/science.1116480
Structure of SARS Coronavirus Spike Receptor-Binding Domain Complexed with Receptor
resolves10.1038/sj.emboj.7600640
Receptor and viral determinants of SARS‐coronavirus adaptation to human ACE2
resolves10.1371/journal.ppat.1003774
Tmprss2 Is Essential for Influenza H1N1 Virus Pathogenesis in Mice
resolves10.1128/JVI.01815-18
TMPRSS2 Contributes to Virus Spread and Immunopathology in the Airways of Murine Models after Coronavirus Infection
resolves10.1007/s00228-020-02963-4
Inhibition of SARS-CoV-2 entry through the ACE2/TMPRSS2 pathway: a promising approach for uncovering early COVID-19 drug therapies
resolves10.1158/2159-8290.CD-20-0451
<i>TMPRSS2</i> and COVID-19: Serendipity or Opportunity for Intervention?
resolves10.1038/s41586-020-2286-9
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
resolves10.1126/science.abb9332
Rapid repurposing of drugs for COVID-19
resolves10.1038/nrc4016
Emerging mechanisms of resistance to androgen receptor inhibitors in prostate cancer
resolves10.1126/science.1168175
Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer
resolves10.1530/ERC-20-0165
COVID-19 and androgen-targeted therapy for prostate cancer patients
resolves10.1128/MCB.26.3.965-975.2006
Phenotypic Analysis of Mice Lacking the <i>Tmprss2</i>-Encoded Protease
resolves10.1016/j.cell.2020.06.010
Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, and Treatment
resolves10.1016/j.cell.2014.08.016
Organoid Cultures Derived from Patients with Advanced Prostate Cancer
resolves10.1126/science.aah4307
<i>SOX2</i> promotes lineage plasticity and antiandrogen resistance in <i>TP53</i> - and <i>RB1</i> -deficient prostate cancer
resolves10.18632/oncotarget.8456
Acquired resistance to the second-generation androgen receptor antagonist enzalutamide in castration-resistant prostate cancer
resolves10.1126/sciimmunol.abc3582
TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes
resolves10.1038/s41591-019-0468-5
A cellular census of human lungs identifies novel cell states in health and in asthma
resolves10.1038/s41591-020-0868-6
SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes
resolves10.15252/embj.2018100300
Long‐term expanding human airway organoids for disease modeling
resolves10.1073/pnas.2003138117
Cell entry mechanisms of SARS-CoV-2
resolves10.1038/s41576-018-0089-8
Chromatin accessibility and the regulatory epigenome
resolves10.1016/j.cell.2020.04.035
SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues
resolves10.1016/j.mce.2009.12.022
Androgen receptor and androgen-dependent gene expression in lung
resolves10.1016/j.annonc.2020.04.479
Androgen-deprivation therapies for prostate cancer and risk of infection by SARS-CoV-2: a population-based study (N = 4532)
resolves10.1016/j.annonc.2020.06.005
On the relationship between androgen-deprivation therapy for prostate cancer and risk of infection by SARS-CoV-2
resolves10.1038/s41577-020-0353-y
Author Correction: Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages
resolves10.14336/AD.2020.0228
Transplantation of ACE2- Mesenchymal Stem Cells Improves the Outcome of Patients with COVID-19 Pneumonia
resolves10.1038/s41582-020-0402-y
Lung innervation in the eye of a cytokine storm: neuroimmune interactions and COVID-19
resolves10.1158/2159-8290.CD-13-1010
The Androgen-Regulated Protease TMPRSS2 Activates a Proteolytic Cascade Involving Components of the Tumor Microenvironment and Promotes Prostate Cancer Metastasis
resolves10.1126/science.abc4730
Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy
resolves10.1016/j.cell.2020.09.050
A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice
resolves10.1172/JCI137967
ERG orchestrates chromatin interactions to drive prostate cell fate reprogramming
resolves10.1038/nmeth.1923
Fast gapped-read alignment with Bowtie 2
resolves10.1093/bioinformatics/btv098
Sambamba: fast processing of NGS alignment formats
resolves10.1093/nar/gkw257
deepTools2: a next generation web server for deep-sequencing data analysis
resolves10.1038/nmeth.4396
An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues
resolves10.1093/bioinformatics/btq033
BEDTools: a flexible suite of utilities for comparing genomic features
resolves10.1126/scisignal.2004088
Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
resolves10.1158/2159-8290.CD-12-0095
The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data
resolves10.1073/pnas.0506580102
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
resolves10.1016/j.cell.2016.02.067
Steroid Receptors Reprogram FoxA1 Occupancy through Dynamic Chromatin Transitions
resolves10.5281/zenodo.4439189
lifei176/ChIP-seq-ATAC-seq: ATAC-seq and ChIP-seq
The 1 reference without a DOI — listed, not checked
no DOI — not checkedWHO. Coronavirus Disease (COVID-19) Weekly Epidemiological Update, (2020, August 31)).
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