Reference health
The antidepressant fluoxetine acts on energy balance and leptin sensitivity via BDNF
76/76 checkable references clean · checked 2026-07-22
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
2 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 76 checked references that resolve
resolves10.1176/appi.ajp.2014.12091165
Clinical Outcomes and Genome-Wide Association for a Brain Methylation Site in an Antidepressant Pharmacogenetics Study in Mexican Americans
resolves10.1016/0092-8674(95)90151-5
Identification and expression cloning of a leptin receptor, OB-R
resolves10.1038/sj.ijo.0801913
The arcuate nucleus as a conduit for diverse signals relevant to energy homeostasis
resolves10.1038/nn.2739
AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training
resolves10.1038/nm1071
Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity
resolves10.1016/j.cmet.2015.10.012
Hypothalamic Amylin Acts in Concert with Leptin to Regulate Food Intake
resolves10.1152/ajpregu.90859.2008
Three weeks of postweaning exercise in DIO rats produces prolonged increases in central leptin sensitivity and signaling
resolves10.1073/pnas.0911832107
A sensitive period for environmental regulation of eating behavior and leptin sensitivity
resolves10.1523/JNEUROSCI.22-04-01316.2002
Brain-Derived Neurotrophic Factor Modulates Cerebellar Plasticity and Synaptic Ultrastructure
resolves10.1073/pnas.92.19.8856
Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor.
resolves10.1016/S0896-6273(00)80316-5
Opposing Roles for Endogenous BDNF and NT-3 in Regulating Cortical Dendritic Growth
resolves10.1073/pnas.96.26.15239
Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities
resolves10.1038/nn1073
Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor
resolves10.2337/db06-0550
Hyperphagia, Severe Obesity, Impaired Cognitive Function, and Hyperactivity Associated With Functional Loss of One Copy of the Brain-Derived Neurotrophic Factor (<i>BDNF</i>) Gene
resolves10.1038/nn1336
A de novo mutation affecting human TrkB associated with severe obesity and developmental delay
resolves10.1016/j.psyneuen.2008.09.015
Chronic fluoxetine treatment increases expression of synaptic proteins in the hippocampus of the ovariectomized rat: Role of BDNF signalling
resolves10.1002/dneu.20758
The role of BDNF and its receptors in depression and antidepressant drug action: Reactivation of developmental plasticity
resolves10.1371/journal.pone.0035901
Neurogenomic Evidence for a Shared Mechanism of the Antidepressant Effects of Exercise and Chronic Fluoxetine in Mice
resolves10.3389/fncel.2011.00025
New Perspectives in Amblyopia Therapy on Adults: A Critical Role for the Excitatory/Inhibitory Balance
resolves10.1523/JNEUROSCI.3741-04.2005
Brain-Derived Neurotrophic Factor and Antidepressant Drugs Have Different But Coordinated Effects on Neuronal Turnover, Proliferation, and Survival in the Adult Dentate Gyrus
resolves10.1126/science.1150516
The Antidepressant Fluoxetine Restores Plasticity in the Adult Visual Cortex
resolves10.1038/srep02217
Fluoxetine treatment promotes functional recovery in a rat model of cervical spinal cord injury
resolves10.1371/journal.pone.0020567
Antidepressant Drugs Transactivate TrkB Neurotrophin Receptors in the Adult Rodent Brain Independently of BDNF and Monoamine Transporter Blockade
resolves10.1186/1475-2891-8-11
Differential susceptibility to obesity between male, female and ovariectomized female mice
resolves10.1016/S0031-9384(03)00035-0
Leptin resistance in mice is determined by gender and duration of exposure to high-fat diet
resolves10.1126/science.1083328
Requirement of Hippocampal Neurogenesis for the Behavioral Effects of Antidepressants
resolves10.1021/ac3016642
Direct Analysis of δ<sup>2</sup>H and δ<sup>18</sup>O in Natural and Enriched Human Urine Using Laser-Based, Off-Axis Integrated Cavity Output Spectroscopy
resolves10.1016/S0014-5793(01)02591-1
Insulin modulates leptin‐induced STAT3 activation in rat hypothalamus
resolves10.1523/JNEUROSCI.5712-08.2009
Enhanced Stat3 Activation in POMC Neurons Provokes Negative Feedback Inhibition of Leptin and InsulinSignaling in Obesity
resolves10.1002/j.1550-8528.1997.tb00287.x
Measurement of Total Carbon Dioxide Production by Means of D<sub>2</sub>O<sup>18</sup><sup>1</sup>
resolves10.1007/BF01617797
Validation of the labeled bicarbonate technique for measurement of short-term energy expenditure in the mouse
resolves10.1007/s40618-014-0225-z
Fuel homeostasis and locomotor behavior: role of leptin and melanocortin pathways
resolves10.1093/ijnp/pyu029
Chronic Fluoxetine Increases Extra-Hippocampal Neurogenesis in Adult Mice
resolves10.1016/j.cmet.2011.06.020
White to Brown Fat Phenotypic Switch Induced by Genetic and Environmental Activation of a Hypothalamic-Adipocyte Axis
resolves10.1152/ajpregu.00021.2009
Adaptive thermogenesis and thermal conductance in wild-type and UCP1-KO mice
resolves10.1016/j.cell.2013.12.021
Ablation of PRDM16 and Beige Adipose Causes Metabolic Dysfunction and a Subcutaneous to Visceral Fat Switch
resolves10.1016/j.bbalip.2013.02.005
White-to-brown transdifferentiation of omental adipocytes in patients affected by pheochromocytoma
resolves10.1038/nn2068
TrkB kinase is required for recovery, but not loss, of cortical responses following monocular deprivation
resolves10.1210/en.2008-1184
Brain-Derived Neurotrophic Factor/Tropomyosin-Related Kinase Receptor Type B Signaling Is a Downstream Effector of the Brainstem Melanocortin System in Food Intake Control
resolves10.1074/jbc.M109.091041
Mutual Regulation of Src Family Kinases and the Neurotrophin Receptor TrkB
resolves10.1016/j.pbb.2016.12.007
Anxiogenic-like effects of fluoxetine render adult male rats vulnerable to the effects of a novel stress
resolves10.1038/tp.2016.25
Is increased antidepressant exposure a contributory factor to the obesity pandemic?
resolves10.1093/ajcn/61.5.1020
Fluoxetine increases resting energy expenditure and basal body temperature in humans
resolves10.1126/science.7624776
Effects of the
<i>obese</i>
Gene Product on Body Weight Regulation in
<i>ob</i>
/
<i>ob</i>
Mice
resolves10.1016/j.cmet.2008.01.007
Activation of Stat3 Signaling in AgRP Neurons Promotes Locomotor Activity
resolves10.2337/diabetes.53.12.3067
LRb-STAT3 Signaling Is Required for the Neuroendocrine Regulation of Energy Expenditure by Leptin
resolves10.1371/journal.pone.0023364
Contrasting Effects of Leptin on Food Anticipatory and Total Locomotor Activity
resolves10.1152/ajpendo.00546.2010
Identification of a physiological role for leptin in the regulation of ambulatory activity and wheel running in mice
resolves10.1016/j.appet.2012.12.023
Differential effects of chronic social stress and fluoxetine on meal patterns in mice
resolves10.1139/apnm-2014-0462
Effect of fluoxetine treatment on mitochondrial bioenergetics in central and peripheral rat tissues
resolves10.1242/jcs.124321
Heterogeneous lineage origin underlies phenotypic and molecular differences of white and beige adipocytes
resolves10.1002/oby.21455
Regionalization of browning revealed by whole subcutaneous adipose tissue imaging
resolves10.1152/ajpregu.00516.2006
Brain-derived neurotrophic factor in the hypothalamic paraventricular nucleus increases energy expenditure by elevating metabolic rate
resolves10.1016/j.brainres.2010.04.013
Brain-derived neurotrophic factor (BDNF) in the hypothalamic ventromedial nucleus increases energy expenditure
resolves10.1016/j.molmet.2015.08.002
Ablation of intact hypothalamic and/or hindbrain TrkB signaling leads to perturbations in energy balance
resolves10.1146/annurev-med-053013-062946
Ketamine and Rapid-Acting Antidepressants: A Window into a New Neurobiology for Mood Disorder Therapeutics
resolves10.2165/11530010-000000000-00000
Role of Brain-Derived Neurotrophic Factor in the Aetiology of Depression
resolves10.1523/JNEUROSCI.23-01-00349.2003
Activation of the TrkB Neurotrophin Receptor Is Induced by Antidepressant Drugs and Is Required for Antidepressant-Induced Behavioral Effects
resolves10.1016/j.yhbeh.2016.01.017
Developmental fluoxetine exposure increases behavioral despair and alters epigenetic regulation of the hippocampal BDNF gene in adult female offspring
The 2 references without a DOI — listed, not checked
no DOI — not checkedGoldstein, D. J. et al. Fluoxetine: a randomized clinical trial in the treatment of obesity. Int J Obes Relat Metab Disord 18, 129–35 (1994).
no DOI — not checkedPatterson, Z. R. & Abizaid, A. Stress induced obesity: lessons from rodent models of stress. Front Neurosci 7, 130 (2013).
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