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Behavioural characterisation of chronic unpredictable stress based on ethologically relevant paradigms in rats
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Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
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The 111 checked references that resolve
resolves10.1016/j.amepre.2005.01.015
Long-Term Consequences of Childhood Sexual Abuse by Gender of Victim
resolves10.1192/bjp.bp.115.180752
Childhood maltreatment and characteristics of adult depression: Meta-analysis
resolves10.1016/j.cobeha.2017.01.001
The effects of stress in early life and adolescence on posttraumatic stress disorder, depression, and anxiety symptomatology in adulthood
resolves10.1016/j.jad.2003.12.013
Adverse childhood experiences and the risk of depressive disorders in adulthood
resolves10.1038/nrn2639
Effects of stress throughout the lifespan on the brain, behaviour and cognition
resolves10.1192/bjp.bp.110.080499
Childhood adversities and adult psychopathology in the WHO World Mental Health Surveys
resolves10.1016/j.neuroscience.2016.05.042
Early-life experiences and the development of adult diseases with a focus on mental illness: The Human Birth Theory
resolves10.1001/archpsyc.62.6.593
Lifetime Prevalence and Age-of-Onset Distributions of DSM-IV Disorders in the National Comorbidity Survey Replication
resolves10.1016/0031-9384(94)90316-6
Effects of chronic mild stress on performance in behavioural tests relevant to anxiety and depression
resolves10.1016/S0006-8993(02)03273-0
Neurochemical and behavioral alterations elicited by a chronic intermittent stressor regimen: implications for allostatic load
resolves10.1016/j.physbeh.2006.12.006
The delayed effects of chronic unpredictable stress on anxiety measures
resolves10.1016/j.neubiorev.2012.07.001
Neurobiology of chronic mild stress: Parallels to major depression
resolves10.1016/0091-3057(82)90053-3
Animal model of depression: Pharmacological sensitivity of a hedonic deficit
resolves10.1007/BF00187257
Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant
resolves10.1016/j.ynstr.2016.08.002
The chronic mild stress (CMS) model of depression: History, evaluation and usage
resolves10.1007/s002130050456
Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation
resolves10.1016/j.ynstr.2016.08.001
Reliability of the chronic mild stress model of depression: A user survey
resolves10.1016/j.pbb.2007.11.004
Differential effect of environment enrichment and social isolation on depressive-like behavior, spontaneous activity and serotonin and norepinephrine concentration in prefrontal cortex and ventral striatum
resolves10.1016/j.neubiorev.2008.03.003
Behavioural and neurochemical effects of post-weaning social isolation in rodents—Relevance to developmental neuropsychiatric disorders
resolves10.1016/j.bbr.2008.10.036
The effect of chronic fluoxetine on social isolation-induced changes on sucrose consumption, immobility behavior, and on serotonin and dopamine function in hippocampus and ventral striatum
resolves10.1007/s002130050706
Effects of isolation-rearing on voluntary consumption of ethanol, sucrose and saccharin solutions in Fawn Hooded and Wistar rats
resolves10.1016/j.bbr.2005.12.001
Factor analysis of Forced Swimming test, Sucrose Preference test and Open Field test on enriched, social and isolated reared rats
resolves10.1016/j.neulet.2008.03.045
Effects of environmental enrichment and social isolation on sucrose consumption and preference: Associations with depressive-like behavior and ventral striatum dopamine
resolves10.1017/S0033291700039593
Neuroendocrine tests of monoamine function in man: a review of basic theory and its application to the study of depressive illness
resolves10.1055/s-2007-979535
The Revised Monoamine Theory of Depression: A Modulatory Role for Monoamines, Based on New Findings From Monoamine Depletion Experiments in Humans
resolves10.1016/0031-9384(81)90320-6
Locomotor activity, defecation score and corticosterone levels during an openfield exposure: A comparison among individually and group-housed rats, and genetically selected rat lines
resolves10.1016/S0031-9384(97)00425-3
Failure to Change Exploration or Saccharin Preference In Rats Exposed to Chronic Mild Stress
resolves10.1037/a0015752
Adolescent male rats exposed to social defeat exhibit altered anxiety behavior and limbic monoamines as adults.
resolves10.1016/S0278-5846(02)00310-X
Gender-specific effects of social housing in rats after chronic mild stress exposure
resolves10.1016/j.bbr.2010.04.041
Strain differences in the chronic mild stress animal model of depression
resolves10.1016/0031-9384(91)90338-O
“Isolation stress” revisited: Isolation-rearing effects depend on animal care methods
resolves10.1016/0014-2999(95)00172-H
Biochemical and behaviour changes induced by acute stress in a chronic variate stress model of depression: the effect of amitriptyline
resolves10.1016/S0014-2999(00)00332-0
Exploratory behaviour and grooming after repeated restraint and chronic mild stress: effect of desipramine
resolves10.1016/j.bbr.2007.03.011
Weaning age, social isolation, and gender, interact to determine adult explorative and social behavior, and dendritic and spine morphology in prefrontal cortex of rats
resolves10.1016/j.neulet.2007.12.041
Prevention of chronic stress-induced depression-like behavior by inducible nitric oxide inhibitor
resolves10.1016/j.bbr.2010.02.026
Long-term treatment with peony glycosides reverses chronic unpredictable mild stress-induced depressive-like behavior via increasing expression of neurotrophins in rat brain
resolves10.1016/j.bbr.2011.03.038
Sex differences and phase of light cycle modify chronic stress effects on anxiety and depressive-like behavior
resolves10.1186/1472-6882-8-15
Evaluation of behavioural and antioxidant activity of Cytisus scoparius Link in rats exposed to chronic unpredictable mild stress
resolves10.1016/0031-9384(87)90182-X
Chronic stress depresses exploratory activity and behavioral performance in the forced swimming test without altering ACTH response to a novel acute stressor
resolves10.1016/0031-9384(94)00286-E
Sucrose consumption as an hedonic measure following chronic unpredictable mild stress
resolves10.1016/S0031-9384(96)00305-8
Chronic Mild Stress and Sucrose Consumption: Validity as a Model of Depression
resolves10.1016/0006-3223(90)90577-O
Dopaminergic mechanism of imipramine action in an animal model of depression
resolves10.1007/BF02244188
An animal model of anhedonia: attenuation of sucrose consumption and place preference conditioning by chronic unpredictable mild stress
resolves10.1016/S0149-7634(05)80192-7
Suppression of sucrose drinking by chronic mild unpredictable stress: A methodological analysis
resolves10.1016/j.bbr.2008.06.008
Chronic mild stress generates clear depressive but ambiguous anxiety-like behaviour in rats
resolves10.1016/j.psyneuen.2009.06.020
Icariin attenuates chronic mild stress-induced dysregulation of the LHPA stress circuit in rats
resolves10.1016/0031-9384(93)90351-F
Chronic mild stress-induced anhedonia: Greater effect in a genetic rat model of depression
resolves10.1016/S0031-9384(98)00060-2
Chronic mild stress has no effect on responding by rats for sucrose under a progressive ratio schedule
resolves10.1016/S0031-9384(97)00042-5
Diurnal Variation in the Effect of Chronic Mild Stress on Sucrose Intake and Preference
resolves10.1016/j.physbeh.2005.06.027
The effects of chronic unpredictable stress on male rats in the water maze
resolves10.1038/npp.2017.11
Adolescent Chronic Unpredictable Stress Exposure Is a Sensitive Window for Long-Term Changes in Adult Behavior in Mice
resolves10.1016/S0006-3223(02)01665-7
Startle reactivity and anxiety disorders: aversive conditioning, context, and neurobiology
resolves10.1016/S0006-3223(01)01255-0
Chronic psychosocial stress impairs learning and memory and increases sensitivity to yohimbine in adult rats
resolves10.1101/lm.850808
Prefrontal cortex and hippocampus subserve different components of working memory in rats
resolves10.1523/JNEUROSCI.3781-16.2017
Chronic-Stress-Induced Behavioral Changes Associated with Subregion-Selective Serotonin Cell Death in the Dorsal Raphe
resolves10.3389/fnbeh.2014.00074
The Sweet Drive Test: refining phenotypic characterization of anhedonic behavior in rodents
resolves10.1007/s00213-007-1035-1
Long-lasting behavioral effects and recognition memory deficit induced by chronic mild stress in mice: effect of antidepressant treatment
resolves10.1016/j.lfs.2008.02.010
Chronic mild stress impairs cognition in mice: From brain homeostasis to behavior
resolves10.1111/j.1365-2826.2011.02109.x
Long Term Sex-Dependent Psychoneuroendocrine Effects of Maternal Deprivation and Juvenile Unpredictable Stress in Rats
resolves10.1016/j.bbadis.2013.09.013
Stress contributes to the development of central insulin resistance during aging: Implications for Alzheimer’s disease
resolves10.1007/s00213-016-4206-0
Antidepressant, anxiolytic and procognitive effects of rivastigmine and donepezil in the chronic mild stress model in rats
resolves10.1097/FBP.0000000000000431
Validation of chronic mild stress in the Wistar-Kyoto rat as an animal model of treatment-resistant depression
resolves10.1111/j.1476-5381.2011.01602.x
Stress‐induced anhedonia is associated with an increase in Alzheimer's disease‐related markers
resolves10.1016/j.beproc.2011.12.004
Novel object exploration in mice: Not all objects are created equal
resolves10.1016/j.pbb.2006.01.004
Impairment of the spatial learning and memory induced by learned helplessness and chronic mild stress
resolves10.1016/0091-3057(94)90472-3
Ethopharmacological analysis of rat behavior on the elevated plus-maze
resolves10.1007/BF02246664
The use of the rat elevated plus-maze to discriminate between non-selective and BZ-1 (ω 1) selective, benzodiazepine receptor ligands
resolves10.1016/S0014-2999(98)00223-4
Changes in head-dipping behavior in the hole-board test reflect the anxiogenic and/or anxiolytic state in mice
resolves10.1016/j.bbr.2013.11.047
Behavioral and neurochemical effects of dietary methyl donor deficiency combined with unpredictable chronic mild stress in rats
resolves10.1038/s41398-018-0171-1
Effect of chronic unpredictable stress on mice with developmental under-expression of the Ahi1 gene: behavioral manifestations and neurobiological correlates
resolves10.1016/S0924-977X(02)80317-0
Combination of chronic mild stress and forced swim test in male and female rats: Behavioral and neurochemical effects
resolves10.1016/0031-9384(89)90261-8
Learned immobility explains the behavior of rats in the forced swimming test
resolves10.1016/0014-2999(78)90118-8
Behavioural despair in rats: A new model sensitive to antidepressant treatments
resolves10.1007/978-3-642-45106-5_9
BDNF and Synaptic Plasticity, Cognitive Function, and Dysfunction
resolves10.4306/pi.2010.7.4.231
The Roles of BDNF in the Pathophysiology of Major Depression and in Antidepressant Treatment
resolves10.1186/1741-7007-4-8
Nucleus accumbens corticotropin-releasing factor increases cue-triggered motivation for sucrose reward: paradoxical positive incentive effects in stress?
resolves10.1016/j.peptides.2009.12.015
Behavioral effects of neuropeptides in rodent models of depression and anxiety
resolves10.1016/j.bbr.2017.09.029
Effects of acute restraint and unpredictable chronic mild stress on brain corticotrophin releasing factor mRNA in the elevated T-maze
resolves10.1016/j.biopsych.2009.02.027
Increased Vulnerability to Depressive-Like Behavior of Mice with Decreased Expression of VGLUT1
resolves10.1007/s00213-010-1835-6
Sustained stress-induced changes in mice as a model for chronic depression
resolves10.1016/j.biopsych.2008.10.025
Amino Acid Neurotransmitters Assessed by Proton Magnetic Resonance Spectroscopy: Relationship to Treatment Resistance in Major Depressive Disorder
resolves10.1001/archgenpsychiatry.2011.131
Anterior Cingulate Cortexγ-Aminobutyric Acid in Depressed Adolescents
resolves10.1002/da.22155
INSULA AND ANTERIOR CINGULATE GABA LEVELS IN POSTTRAUMATIC STRESS DISORDER: PRELIMINARY FINDINGS USING MAGNETIC RESONANCE SPECTROSCOPY
resolves10.1038/npp.2012.4
Reduced γ-Aminobutyric Acid in Occipital and Anterior Cingulate Cortices in Primary Insomnia: a Link to Major Depressive Disorder?
resolves10.1007/s002130050465
Blunting of reactivity of dopamine transmission to palatable food: a biochemical marker of anhedonia in the CMS model?
resolves10.1016/j.bbr.2008.08.014
A detailed analysis of open-field habituation and behavioral and neurochemical antidepressant-like effects in postweaning enriched rats
resolves10.1016/j.anbehav.2018.01.018
Testing experience and environmental enrichment potentiated open-field habituation and grooming behaviour in rats
resolves10.1016/0165-0270(85)90031-7
Validation of open : closed arm entries in an elevated plus-maze as a measure of anxiety in the rat
resolves10.1016/0166-4328(96)00067-8
Detection of serotonergic and noradrenergic antidepressants in the rat forced swimming test: the effects of water depth
resolves10.1177/014662168500900205
An Empirical Test of the Utility of the Observations-To-Variables Ratio in Factor and Components Analysis
resolves10.1016/0924-977X(92)90035-7
Antidepressant treatment prevents chronic unpredictable mild stress-induced anhedonia as assessed by ventral tegmentum self-stimulation behavior in rats
resolves10.1046/j.1460-9568.1998.00201.x
Mesolimbic dopaminergic mechanisms underlying individual differences in sugar consumption and amphetamine hyperlocomotion in Wistar rats
resolves10.1007/s002130050024
Self-administration of intravenous amphetamine is predicted by individual differences in sucrose feeding in rats
resolves10.1002/cne.23842
Differential effects of social and physical environmental enrichment on brain plasticity, cognition, and ultrasonic communication in rats
resolves10.3758/BF03200814
EthoLog 2.2: A tool for the transcription and timing of behavior observation sessions
resolves10.1186/gb-2007-8-2-r19
qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data
resolves10.1016/j.bbr.2012.09.028
Maternal behavior as an early modulator of neurobehavioral offspring responses by Sprague-Dawley rats
resolves10.1016/j.physbeh.2014.01.037
Individual differences in the forced swimming test and neurochemical kinetics in the rat brain
The 5 references without a DOI — listed, not checked
no DOI — not checkedBrown, G. W., Harris, T. O. & Craig, T. K. J. Exploration of the influence of insecure attachment and parental maltreatment on the incidence and course of adult clinical depression. Psychol. Med. 15, 1–8 (2018).
no DOI — not checkedWorld Health Organization. International classification of diseases for mortality and morbidity statistics (11th Revision). Retrieved from, https://icd.who.int/browse11/l-m/en (2018).
no DOI — not checkedSmagin, G. N., Howell, L. A., Redmann, S., Ryan, D. H. & Harris, R. B. Prevention of stress-induced weight loss by third ventricle CRF receptor antagonist. Am. J. Physiol. 276, R1461–R1468 (1999).
no DOI — not checkedMoret, C. & Briley, M. The importance of norepinephrine in depression. Neuropsychiatr. Dis. Treatment. 7, 9–13 (2011).
no DOI — not checkedField, A.P. Discovering Statistics Using SPSS: (and Sex and Drugs and Rock ‘n’ Roll). OKS Print. Los Angeles [i.e. Thousand Oaks, Calif.]: SAGE Publications (2009).
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