Reference health
Phytochemical mediated modulation of COX-3 and NFκB for the management and treatment of arthritis
1 of 52 checkable references need attention · checked 2026-07-23
At the dated check, the references listed below either did not resolve in Crossref or DataCite, or carried a retraction notice. Each one is shown with the registry record that put it there.
13 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
References needing attention
marked retracted — notice via Crossref, record curated by Retraction Watch10.1155/2022/3848084
[Retracted] Ellagic Acid: A Review on Its Natural Sources, Chemical Stability, and Therapeutic Potential
The 51 checked references that resolve
resolves10.1161/CIRCULATIONAHA.114.011591
Evidence That Links Loss of Cyclooxygenase-2 With Increased Asymmetric Dimethylarginine
resolves10.1038/sj.bjp.0701672
Effects of inhibition of prostaglandin endoperoxide synthase‐2 in chronic gastro‐intestinal ulcer models in rats
resolves10.1016/j.jare.2020.05.021
Modulation of proteomic and inflammatory signals by Bradykinin in podocytes
resolves10.1358/dot.1999.35.4-5.552200
Structure of COX-1 and COX-2 enzymes and their interaction with
inhibitors
resolves10.1073/pnas.162468699
COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure, and expression
resolves10.1016/j.jare.2020.02.014
Etoricoxib prevents progression of osteolysis in repeated intra-articular monosodium urate-induced gouty arthritis in rats
resolves10.1002/art.10356
Cyclooxygenase 2‐dependent prostaglandin E<sub>2</sub> modulates cartilage proteoglycan degradation in human osteoarthritis explants
resolves10.1053/joca.1999.0266
Induction of apoptosis in bovine articular chondrocyte by prostaglandin E2through cAMP-dependent pathway
resolves10.1155/2014/920742
Biomedical Properties of a Natural Dietary Plant Metabolite, Zerumbone, in Cancer Therapy and Chemoprevention Trials
resolves10.1093/carcin/23.5.795
Zerumbone, a Southeast Asian ginger sesquiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation accompanied by apoptosis: the alpha,beta-unsaturated carbonyl group is a prerequisite
resolves10.1016/j.indcrop.2018.01.006
Zingiber zerumbet (L.) Roscoe ex Sm. from northern India: Potential source of zerumbone rich essential oil for antiproliferative and antibacterial applications
resolves10.1038/sj.onc.1208845
Zerumbone abolishes NF-κB and IκBα kinase activation leading to suppression of antiapoptotic and metastatic gene expression, upregulation of apoptosis, and downregulation of invasion
resolves10.1016/j.jep.2014.12.074
Past, present and perspectives of Manipur traditional medicine: A major health care system available for rural population in the North-East India
resolves10.1016/j.jep.2012.06.025
Evaluation of mechanism for antihypertensive action of Clerodendrum colebrookianum Walp., used by folklore healers in north-east India
resolves10.18632/oncotarget.4475
The antidiabetic compound 2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione, isolated from<i>averrhoa carambola</i>L., demonstrates significant antitumor potential against human breast cancer cells
resolves10.1055/s-2005-837820
Antitumor Effects of Zerumbone from<i>Zingiber zerumbet</i>in P-388D<sub>1</sub>Cells<i>in Vitro</i>and<i>in Vivo</i>
resolves10.1111/j.1745-4530.2007.00169.x
A NEW METHOD FOR ELLAGIC ACID PRODUCTION FROM POMEGRANATE HUSK
resolves10.1016/j.sjbs.2011.04.002
Protease inhibitor from Moringa oleifera with potential for use as therapeutic drug and as seafood preservative
resolves10.1080/07391102.2015.1051114
Exploration of new drug-like inhibitors for serine/threonine protein phosphatase 5 of<i>Plasmodium falciparum</i>: a docking and simulation study
resolves10.1016/j.jare.2020.02.007
Discovery of novel and potent P2Y14R antagonists via structure-based virtual screening for the treatment of acute gouty arthritis
resolves10.1080/07391102.2015.1108870
Exploring dual inhibitors for STAT1 and STAT5 receptors utilizing virtual screening and dynamics simulation validation
resolves10.1080/07391102.2015.1110046
<i>In</i>-<i>silico</i> identification of inhibitors against mutated BCR-ABL protein of chronic myeloid leukemia: a virtual screening and molecular dynamics simulation study
resolves10.1038/aps.2008.20
Suppression of complete Freund's adjuvant-induced adjuvant arthritis by cobratoxin
resolves10.3390/ijms17060849
Protective Effect of Ginsenoside Rg1 on Hematopoietic Stem/Progenitor Cells through Attenuating Oxidative Stress and the Wnt/β-Catenin Signaling Pathway in a Mouse Model of d-Galactose-induced Aging
resolves10.1016/j.toxrep.2014.05.014
Quercetin inhibits the cytotoxicity and oxidative stress in liver of rats fed aflatoxin-contaminated diet
resolves10.1016/j.ygcen.2004.10.013
Melatonin accelerates maturation inducing hormone (MIH): induced oocyte maturation in carps
resolves10.1016/j.scitotenv.2018.02.101
Artificial Light at Night (ALAN), an alarm to ovarian physiology: A study of possible chronodisruption on zebrafish (Danio rerio)
resolves10.1016/j.cbpa.2008.11.010
Localization and dynamics of Mel1a melatonin receptor in the ovary of carp Catla catla in relation to serum melatonin levels
resolves10.1016/S1093-3263(97)00107-1
Comparative molecular modeling study of the three-dimensional structures of prostaglandin endoperoxide H2 synthase 1 and 2 (COX-1 and COX-2)
resolves10.1016/S0140-6736(99)12031-2
COX-1, COX-2, and COX-3 and the future treatment of chronic inflammatory disease
resolves10.1615/CritRevImmunol.v32.i1.30
Role of Interleukin 10 Transcriptional Regulation in Inflammation and Autoimmune Disease
resolves10.1016/j.clim.2013.04.008
Inflammasome and cytokine blocking strategies in autoinflammatory disorders
resolves10.1186/ar300
resolves10.3390/ijms16022747
Binding Mode Analysis of Zerumbone to Key Signal Proteins in the Tumor Necrosis Factor Pathway
resolves10.1093/emboj/16.23.7078
Structure of the human NF‐κB p52 homodimer‐DNA complex at 2.1 Å resolution
resolves10.1186/1472-6807-8-38
Docking of molecules identified in bioactive medicinal plants extracts into the p50 NF-kappaB transcription factor: correlation with inhibition of NF-kappaB/DNA interactions and inhibitory effects on IL-8 gene expression
resolves10.1155/2020/8825387
Quercetin: Its Main Pharmacological Activity and Potential Application in Clinical Medicine
resolves10.1016/j.prostaglandins.2007.10.007
Acetaminophen: Antipyretic or hypothermic in mice? In either case, PGHS-1b (COX-3) is irrelevant
resolves10.1023/B:NERE.0000035809.70905.8a
Cyclooxygenase-3 Gene Expression in Alzheimer Hippocampus and in Stressed Human Neural Cells
resolves10.1007/s11060-015-1976-x
Therapeutic potential of cyclooxygenase-3 inhibitors in the management of glioblastoma
The 13 references without a DOI — listed, not checked
no DOI — not checkedQin, N., Codd, E., Flores, C. & Zhang, S. P. Human cyclooxygenase-3 enzyme and uses thereof. Washington, DC: U.S. Patent and Trademark Office. U.S. Patent. No. 10/783297 (2004).
no DOI — not checkedDaniel, A. B. & Ben, G. Biological Therapeutics, Treatment of Rheumatoid Arthritis and Other Inflammatory disorders with Biological Drugs (First edition) 89–102 (Pharmaceutical Press, 2011).
no DOI — not checkedDeore, S., Nichole, K., Baviskar, B. A. & Khadabadi, S. S. Isolation and quantitative estimation of quercetin in Lagenaria siceraria fruit. J Chromatogr. Separ. Tech. 4(191), 2 (2013).
no DOI — not checkedDas, B. et al. Antioxidant and anti-inflammatory activity of aqueous and methanolic extracts of rhizome part of Drynaria quercifolia (L.). J. Smith. Int. J. Pharm. Pharm. Sci. 6(6), 43–49 (2014).
no DOI — not checkedSimmons, D. & Chandrasekharan, N. V. Cyclooxygenase variants and methods of use. Washington, DC: U.S. Patent and Trademark Office. U.S. Patent; No. 7179627 (2007).
no DOI — not checkedSimmons, D. & Chandrasekharan, N. V. Antibodies to cyclooxygenase variants. Washington, DC: U.S. Patent and Trademark Office. U.S. Patent. No. 7601816 (2009).
no DOI — not checkedSimmons, D. L., Lee, J. J, Hunter, J. C. & Logon, G. Use of cox-3 binding molecules for modulating autophagy. U.S. Patent. No. 14/505338 (2015).
no DOI — not checkedNagini, M., Reddy, G. V., Hemalatha, G. R., Guruprasad, L. & Reddanna, P. Functional correlation of cyclooxygenases-l, 2 and 3 from amino acid sequences and three-dimensional model structures. Indian J. Chem. 45A(1), 182–187 (2006).
no DOI — not checkedGupta, S., Rao, A. R., Varadwaj, P. K., De, S. & Mohapatra, T. Extrapolation of inter domain communications and substrate binding cavity of camel HSP70 1A: A molecular modeling and dynamics simulation study. PLoS ONE 10(8), e0136630 (2015).
no DOI — not checkedGirish, C., Shweta, O., Raj, V., Balakrishnan, S. & Varghese, R. G. Ellagic acid modulates sodium valproate induced reproductive toxicity in male Wistar rats. Indian J. Physiol. Pharmacol. 58(4), 416–422 (2014).
no DOI — not checkedTeam RC. R: A language and environment for statistical computing. R Foundation for Statistical Computing,
Vienna. http://www.R-project.org/ (2013).
no DOI — not checkedLaw, M., Corsino, P., Parker, T. N. & Law, B. K. Identification of a small molecule inhibitor of serine 276 phosphorylation of the p65 subunit of NF-κB using in silico molecular docking. Cancer Lett. 29, 217–224 (2011).
no DOI — not checkedSafa, A. E. Zerumbone and Small Interference RNA Induce Apoptosis in MCF-7 Cell and Rat Mammary Gland Tumour via β-Catenin Protein Inhibition. Ph.D. Thesis, Universiti Puta Malaysia, Kuala Lumpur, Malaysia (2013).
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