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Calcitonin Gene–Related Peptide Receptor Antagonist BIBN 4096 BS for the Acute Treatment of Migraine

https://doi.org/10.1056/nejmoa030505
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29/29 checkable references clean · checked 2026-07-23

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

5 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 29 checked references that resolve
resolves10.1046/j.1526-4610.2001.041007646.x
Prevalence and Burden of Migraine in the United States: Data From the American Migraine Study II
resolves10.1212/WNL.42.6.1225
Symptomatic and nonsymptomatic headaches in a general population
resolves10.1001/archneur.57.3.418
The Global Burden of Disease Study
resolves10.1056/NEJMra010917
Migraine — Current Understanding and Treatment
resolves10.1046/j.1468-2982.1996.1605310.x
Calcitonin Gene-Related Peptide is Released from Capsaicin-Sensitive Nerve Fibres and Induces Vasodilatation of Human Cerebral Arteries Concomitant with Activation of Adenylyl Cyclase
resolves10.1046/j.1468-2982.1997.1704518.x
Intravital Microscope Studies on the Effects of Neurokinin Agonists and Calcitonin Gene-Related Peptide on Dural Vessel Diameter in the Anaesthetized Rat
resolves10.1002/ana.410280213
Vasoactive peptide release in the extracerebral circulation of humans during migraine headache
resolves10.1046/j.1468-2982.2002.00310.x
Cgrp May Play A Causative Role in Migraine
resolves10.1038/sj.bjp.0703110
Pharmacological profile of BIBN4096BS, the first selective small molecule CGRP antagonist
resolves10.1016/S0028-3908(02)00008-4
Efficacy of the non-peptide CGRP receptor antagonist BIBN4096BS in blocking CGRP-induced dilations in human and bovine cerebral arteries: potential implications in acute migraine treatment
resolves10.1201/9781584888581
Group Sequential Methods
resolves10.1002/sim.4780140909
AN EXTENSION OF THE CONTINUAL REASSESSMENT METHODS USING A PRELIMINARY UP‐AND‐DOWN DESIGN IN A DOSE FINDING STUDY IN CANCER PATIENTS, IN ORDER TO INVESTIGATE A GREATER RANGE OF DOSES
resolves10.1002/1531-8249(200002)47:2<238::AID-ANA15>3.0.CO;2-L
No acute antimigraine efficacy of CP-122,288, a highly potent inhibitor of neurogenic inflammation: Results of two randomized, double-blind, placebo-controlled clinical trials
resolves10.1056/NEJM200105243442106
Is the Placebo Powerless?
resolves10.1046/j.1468-2982.2000.00117.x
Guidelines for Controlled Trials of Drugs in Migraine: Second Edition
resolves10.1046/j.1468-2982.2003.00528.x
Placebo Response in Clinical Randomized Trials of Analgesics in Migraine
resolves10.1016/0196-9781(92)90084-G
Distribution and effects of neuropeptide Y, vasoactive intestinal peptide, substance P, and calcitonin gene-related peptide in human middle meningeal arteries: Comparison with cerebral and temporal arteries
resolves10.1016/0304-3940(85)90296-4
Innervation of the feline cerebral vasculature by nerve fibers containing calcitonin gene-related peptide: Trigeminal origin and co-existence with substance P
resolves10.1002/ana.410200409
Localization and effects of neuropeptide Y, vasoactive intestinal polypeptide, substance P, and calcitonin gene–related peptide in human temporal arteries
resolves10.1002/ana.410230214
Release of vasoactive peptides in the extracerebral circulation of humans and the cat during activation of the trigeminovascular system
resolves10.1016/0143-4179(90)90114-E
Stimulation of the superior sagittal sinus in the cat causes release of vasoactive peptides
resolves10.1016/0028-3908(91)90165-8
Dihydroergotamine and sumatriptan attenuate levels of CGRP in plasma in rat superior sagittal sinus during electrical stimulation of the trigeminal ganglion
resolves10.1002/ana.410330109
The trigeminovascular system and migraine: Studies characterizing cerebrovascular and neuropeptide changes seen in humans and cats
resolves10.1056/NEJM199108013250504
Treatment of Migraine Attacks with Sumatriptan
resolves10.1016/S0301-0082(00)00010-1
The pharmacology of headache
resolves10.1046/j.1468-2982.1997.1704525.x
Sumatriptan Inhibits Neurogenic Vasodilation of Dural Blood Vessels in the Anaesthetized Rat—Intravital Microscope Studies
resolves10.1038/sj.bjp.0704842
Nitric oxide synthase inhibitors can antagonize neurogenic and calcitonin gene‐related peptide induced dilation of dural meningeal vessels
resolves10.1093/brain/120.12.2171
Microiontophoretic application of serotonin (5HT)1B/1D agonists inhibits trigeminal cell firing in the cat
resolves10.1016/S0140-6736(01)06711-3
Oral triptans (serotonin 5-HT1B/1D agonists) in acute migraine treatment: a meta-analysis of 53 trials
The 5 references without a DOI — listed, not checked
no DOI — not checkedEdvinsson L, Krause DN, eds. Cerebral blood flow and metabolism. 2nd ed. Philadelphia: Lippincott Williams & Wilkins, 2002.
no DOI — not checkedr012
no DOI — not checkedr030
no DOI — not checkedr033
no DOI — not checkedr034
What this badge says. CiteStamped means the CHECKABLE references of this work were clean at the dated check: each resolved to a known work in a public registry, and none carried a retraction notice at that time. It says nothing about the quality, findings, or importance of the work itself, and nothing about references deposited without a DOI.

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