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Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from <i>BRCA</i> Mutation Carriers

https://doi.org/10.1056/nejmoa0900212
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30/30 checkable references clean · checked 2026-07-24

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

The 30 checked references that resolve
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Base Excision Repair Is Impaired in Mammalian Cells Lacking Poly(ADP-ribose) Polymerase-1
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Deficiency in the Repair of DNA Damage by Homologous Recombination and Sensitivity to Poly(ADP-Ribose) Polymerase Inhibition
resolves10.1038/sj.onc.1209874
The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability
resolves10.1056/NEJMra012284
Breast and Ovarian Cancer
resolves10.1056/NEJM199704173361602
Contribution of<i>BRCA1</i>Mutations to Ovarian Cancer
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Two Percent of Men with Early-Onset Prostate Cancer Harbor Germline Mutations in the BRCA2 Gene
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Exploiting the DNA Repair Defect in BRCA Mutant Cells in the Design of New Therapeutic Strategies for Cancer
resolves10.1056/NEJMcibr052331
Treating Cancer by Targeting a Weakness
resolves10.1158/1078-0432.CCR-07-4953
Selective Inhibition of BRCA2-Deficient Mammary Tumor Cell Growth by AZD2281 and Cisplatin
resolves10.1021/jm8001263
4-[3-(4-Cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2<i>H</i>-phthalazin-1-one: A Novel Bioavailable Inhibitor of Poly(ADP-ribose) Polymerase-1
resolves10.1093/jnci/89.15.1138
Accelerated Titration Designs for Phase I Clinical Trials in Oncology
resolves10.1038/sj.bjc.6602558
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resolves10.4161/cc.2.5.509
Focusing on Foci: H2AX and the Recruitment of DNA-Damage Response Factors
resolves10.1038/nrc1691
The Concept of Synthetic Lethality in the Context of Anticancer Therapy
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A Growing Network of Cancer-Susceptibility Genes
resolves10.1038/sj.onc.1210014
BRCA1 dysfunction in sporadic basal-like breast cancer
resolves10.1186/1471-2407-8-17
Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalities
resolves10.1038/nature06548
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resolves10.1038/nature06633
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