Reference health
Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression
1 of 70 checkable references need attention · checked 2026-07-22
At the dated check, the references listed below either did not resolve in Crossref or DataCite, or carried a retraction notice. Each one is shown with the registry record that put it there.
4 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
References needing attention
does not resolve to a known work10.1002/(SICI)1097-4644(19981101)71:2<254::AID-JCB10>3.0.CO;2-L
The 69 checked references that resolve
resolves10.1016/S0002-9440(10)65334-5
The Compliance of Collagen Gels Regulates Transforming Growth Factor-β Induction of α-Smooth Muscle Actin in Fibroblasts
resolves10.1016/j.tcb.2008.05.002
Growth control by intracellular tension and extracellular stiffness
resolves10.1152/japplphysiol.00272.2003
Selected Contribution: Airway contractility and smooth muscle Ca<sup>2</sup><sup>+</sup> signaling in lung slices from different mouse strains
resolves10.1016/S0002-9440(10)64202-2
Susceptibility of Cyclooxygenase-2-Deficient Mice to Pulmonary Fibrogenesis
resolves10.1164/ajrccm/144.5.1080
Augmentation of Functional Prostaglandin E Levels on the Respiratory Epithelial Surface by Aerosol Administration of Prostaglandin E
resolves10.2170/jjphysiol.36.91
Poissons' ratio of lung parenchyma and parenchymal interaction with bronchi.
resolves10.1128/MCB.01776-08
Defective Histone Acetylation Is Responsible for the Diminished Expression of Cyclooxygenase 2 in Idiopathic Pulmonary Fibrosis
resolves10.1097/01.LAB.0000101911.53973.90
Normal and Pathologic Soft Tissue Remodeling: Role of the Myofibroblast, with Special Emphasis on Liver and Kidney Fibrosis
resolves10.1016/S0021-9258(18)80098-9
Transforming growth factor-β stimulation of lung fibroblast prostaglandin E2 production
resolves10.1074/jbc.273.35.22554
cAMP-induced Morphological Changes Are Counteracted by the Activated RhoA Small GTPase and the Rho Kinase ROKα
resolves10.1111/1523-1747.ep12274528
Mechanical Analysis of Hypertrophic Scar Tissue: Structural Basis for Apparent Increased Rigidity
resolves10.1164/ajrccm.162.4.9912011
Changes in Extracellular Matrix and Tissue Viscoelasticity in Bleomycin–induced Lung Fibrosis
resolves10.1165/rcmb.2007-0438OC
16,16-Dimethyl Prostaglandin E2 Efficacy on Prevention and Protection from Bleomycin-Induced Lung Injury and Fibrosis
resolves10.1126/science.1168441
Mechanically Activated Integrin Switch Controls α
<sub>5</sub>
β
<sub>1</sub>
Function
resolves10.1152/ajpgi.00032.2007
Increased stiffness of the rat liver precedes matrix deposition: implications for fibrosis
resolves10.1074/jbc.M503173200
Myosin Phosphatase and Cofilin Mediate cAMP/cAMP-dependent Protein Kinase-induced Decline in Endothelial Cell Isometric Tension and Myosin II Regulatory Light Chain Phosphorylation
resolves10.1083/jcb.200506179
Focal adhesion size controls tension-dependent recruitment of α-smooth muscle actin to stress fibers
resolves10.1529/biophysj.104.047365
Directional Persistence of EGF-Induced Cell Migration Is Associated with Stabilization of Lamellipodial Protrusions
resolves10.1016/S0002-9440(10)63423-2
Severity of Lung Injury in Cyclooxygenase-2-Deficient Mice Is Dependent on Reduced Prostaglandin E2 Production
resolves10.1152/ajplung.00232.2006
Prostaglandin E<sub>2</sub>inhibits collagen expression and proliferation in patient-derived normal lung fibroblasts via E prostanoid 2 receptor and cAMP signaling
resolves10.1016/j.bpj.2009.06.021
Vascular Smooth Muscle Cell Durotaxis Depends on Substrate Stiffness Gradient Strength
resolves10.1124/mol.105.021600
Transforming Growth Factor-β Receptor Type 1 (TGFβRI) Kinase Activity but Not p38 Activation Is Required for TGFβRI-Induced Myofibroblast Differentiation and Profibrotic Gene Expression
resolves10.1016/S0002-9440(10)64092-8
Cyclooxygenase-2 Deficiency Results in a Loss of the Anti-Proliferative Response to Transforming Growth Factor-β in Human Fibrotic Lung Fibroblasts and Promotes Bleomycin-Induced Pulmonary Fibrosis in Mice
resolves10.1165/rcmb.2002-0243OC
Prostaglandin E2 Inhibits Fibroblast to Myofibroblast Transition via E. Prostanoid Receptor 2 Signaling and Cyclic Adenosine Monophosphate Elevation
resolves10.1172/JCI110873
Fibroblast prostaglandin E2 synthesis. Persistence of an abnormal phenotype after short-term exposure to mononuclear cell products.
resolves10.1165/rcmb.4857
Prostaglandin E
<b>2</b>
Synthesis and Suppression of Fibroblast Proliferation by Alveolar Epithelial Cells Is Cyclooxygenase-2–Dependent
resolves10.1002/j.1460-2075.1996.tb00383.x
Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes.
resolves10.1016/j.yexcr.2007.04.022
Cell shape regulates global histone acetylation in human mammary epithelial cells
resolves10.1002/hep.21792
Transforming growth factor-β and substrate stiffness regulate portal fibroblast activation in culture
resolves10.1016/j.prostaglandins.2008.10.002
Celecoxib exacerbates hepatic fibrosis and induces hepatocellular necrosis in rats treated with porcine serum
resolves10.1152/ajplung.00492.2005
COX-2-derived prostacyclin protects against bleomycin-induced pulmonary fibrosis
resolves10.7326/0003-4819-142-12_Part_1-200506210-00005
The Clinical Course of Patients with Idiopathic Pulmonary Fibrosis
resolves10.1042/bj3070063
Regulation of fibroblast procollagen production. Transforming growth factor-<i>β</i>1 induces prostaglandin E2 but not procollagen synthesis via a pertussis toxin-sensitive G-protein
resolves10.1152/ajpgi.00465.2002
Inhibition of sustained smooth muscle contraction by PKA and PKG preferentially mediated by phosphorylation of RhoA
resolves10.1038/nm.2066
Prostaglandin F2α receptor signaling facilitates bleomycin-induced pulmonary fibrosis independently of transforming growth factor-β
resolves10.1152/jappl.1987.62.1.219
Cyclooxygenase metabolites are compartmentalized in the human lower respiratory tract
resolves10.1073/pnas.94.25.13661
Cell locomotion and focal adhesions are regulated by substrate flexibility
resolves10.1002/jemt.20400
Three‐dimensional investigation and scoring of extracellular matrix remodeling during lung fibrosis using multiphoton microscopy
resolves10.1002/jcp.20274
Extracellular matrix rigidity governs smooth muscle cell motility in a biphasic fashion
resolves10.1111/j.1524-475X.2006.00193.x
Prostaglandin E2 inhibition of keloid fibroblast migration, contraction, and transforming growth factor (TGF)‐β1–induced collagen synthesis
resolves10.7326/0003-4819-134-2-200101160-00015
Idiopathic Pulmonary Fibrosis: Prevailing and Evolving Hypotheses about Its Pathogenesis and Implications for Therapy
resolves10.1038/nm1685
The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak
resolves10.1152/ajplung.00489.2006
PGE<sub>2</sub>inhibition of TGF-β1-induced myofibroblast differentiation is Smad-independent but involves cell shape and adhesion-dependent signaling
resolves10.1063/1.111407
Thermal and ambient-induced deflections of scanning force microscope cantilevers
resolves10.1165/ajrcmb.22.5.3948
Different Expression of TNF-α Receptors and Prostaglandin E2Production in Normal and Fibrotic Lung Fibroblasts: Potential Implications for the Evolution of the Inflammatory Process
resolves10.1152/ajpcell.2000.279.5.C1345
Substrate flexibility regulates growth and apoptosis of normal but not transformed cells
resolves10.1002/jcb.22242
Prostaglandin E<sub>2</sub> inhibits the proliferation of human gingival fibroblasts via the EP<sub>2</sub> receptor and Epac
resolves10.1172/JCI117866
Cultured lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis have a diminished capacity to synthesize prostaglandin E2 and to express cyclooxygenase-2.
resolves10.1083/jcb.200704042
Myofibroblast contraction activates latent TGF-β1 from the extracellular matrix
resolves10.1021/la026403p
Directed Movement of Vascular Smooth Muscle Cells on Gradient-Compliant Hydrogels
resolves10.1002/cm.20041
Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion
The 4 references without a DOI — listed, not checked
no DOI — not checkedThe roles of the myofibroblast in idiopathic pulmonary fibrosis. Ultrastructural and immunohistochemical features of sites of active extracellular matrix synthesis
no DOI — not checkedPoisson’s ratio in polymer gels near the phase-transition point
no DOI — not checkedCyclooxygenase-2 is up-regulated in lung parenchyma of chronic obstructive pulmonary disease and down-regulated in idiopathic pulmonary fibrosis
no DOI — not checkedMyofibroblasts and their role in lung collagen gene expression during pulmonary fibrosis. A combined immunohistochemical and in situ hybridization study
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