Reference health
Rapid Adaptation Often Occurs through Mutations to the Most Highly Conserved Positions of the RNA Polymerase Core Enzyme
44/44 checkable references clean · checked 2026-07-22
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
3 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 44 checked references that resolve
resolves10.1093/molbev/msx118
Rapid Genetic Adaptation during the First Four Months of Survival under Resource Exhaustion
resolves10.1128/JB.00784-18
Experimental Evolution of Extreme Resistance to Ionizing Radiation in
<i>Escherichia coli</i>
after 50 Cycles of Selection
resolves10.1093/bioinformatics/btm270
Predicting functionally important residues from sequence conservation
resolves10.1371/journal.pgen.1001186
Genetic Basis of Growth Adaptation of Escherichia coli after Deletion of pgi, a Major Metabolic Gene
resolves10.1093/bioinformatics/btq007
PyRosetta: a script-based interface for implementing molecular modeling algorithms using Rosetta
resolves10.1093/bioinformatics/btp163
Biopython: freely available Python tools for computational molecular biology and bioinformatics
resolves10.1073/pnas.0911253107
RNA polymerase mutants found through adaptive evolution reprogram
<i>Escherichia coli</i>
for optimal growth in minimal media
resolves10.1038/35037572
The population genetics of ecological specialization in evolving Escherichia coli populations
resolves10.1128/JB.183.15.4543-4550.2001
<i>Escherichia coli</i>
RNA Polymerase Is the Target of the Cyclopeptide Antibiotic Microcin J25
resolves10.1093/nar/gky482
The RNA polymerase clamp interconverts dynamically among three states and is stabilized in a partly closed state by ppGpp
resolves10.1093/gbe/evv102
Alarmingly High Segregation Frequencies of Quinolone Resistance Alleles within Human and Animal Microbiomes Are Not Explained by Direct Clinical Antibiotic Exposure
resolves10.3389/fgene.2015.00042
Rapid evolution of silver nanoparticle resistance in Escherichia coli
resolves10.1093/gbe/evaa210
Culture Volume Influences the Dynamics of Adaptation under Long-Term Stationary Phase
resolves10.1128/AEM.03494-14
Acid-Adapted Strains of Escherichia coli K-12 Obtained by Experimental Evolution
resolves10.1038/ng1906
Comparative genome sequencing of Escherichia coli allows observation of bacterial evolution on a laboratory timescale
resolves10.1016/j.tig.2017.05.003
Antibiotic-Independent Adaptive Effects of Antibiotic Resistance Mutations
resolves10.1093/molbev/msab067
Dynamics of Adaptation During Three Years of Evolution Under Long-Term Stationary Phase
resolves10.1371/journal.pgen.1003972
Whole Genome, Whole Population Sequencing Reveals That Loss of Signaling Networks Is the Major Adaptive Strategy in a Constant Environment
resolves10.1186/s40168-016-0162-5
Marker genes that are less conserved in their sequences are useful for predicting genome-wide similarity levels between closely related prokaryotic strains
resolves10.1073/pnas.0307195101
The evolution of a pleiotropic fitness tradeoff in
<i>Pseudomonas fluorescens</i>
resolves10.1371/journal.pbio.1000483
Complete Structural Model of Escherichia coli RNA Polymerase from a Hybrid Approach
resolves10.1093/genetics/156.4.1471
Compensatory Evolution in Rifampin-Resistant <i>Escherichia coli</i>
resolves10.1093/molbev/msv228
First-Step Mutations during Adaptation Restore the Expression of Hundreds of Genes
resolves10.1371/journal.pone.0151130
Evolution of E. coli on [U-13C]Glucose Reveals a Negligible Isotopic Influence on Metabolism and Physiology
resolves10.1016/S0021-9258(18)82407-3
Rifampicin region revisited. New rifampicin-resistant and streptolydigin-resistant mutants in the beta subunit of Escherichia coli RNA polymerase
resolves10.1128/AAC.01060-12
Frequency, Spectrum, and Nonzero Fitness Costs of Resistance to Myxopyronin in Staphylococcus aureus
resolves10.1128/ecosalplus.ESP-0004-2018
An Introduction to the Structure and Function of the Catalytic Core Enzyme of
<i>Escherichia coli</i>
RNA Polymerase
resolves10.1073/pnas.0804739105
Accumulation of mutants in “aging” bacterial colonies is due to growth under selection, not stress-induced mutagenesis
resolves10.1016/S0092-8674(00)81515-9
Crystal Structure of Thermus aquaticus Core RNA Polymerase at 3.3 Å Resolution
resolves10.1038/s41598-019-47427-7
Escherichia coli adaptation and response to exposure to heavy atmospheric pollution
The 3 references without a DOI — listed, not checked
no DOI — not checked2022090906585169700_evac105-B6
no DOI — not checked2022090906585169700_evac105-B32
no DOI — not checkedEnsembl 2020
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