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RANKL induces Bach1 nuclear import and attenuates Nrf2‐mediated antioxidant enzymes, thereby augmenting intracellular reactive oxygen species signaling and osteoclastogenesis in mice

https://doi.org/10.1096/fj.201600826r
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37/37 checkable references clean · checked 2026-07-24

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

2 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 37 checked references that resolve
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Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation
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Stimulation of osteoclastic bone resorption by hydrogen peroxide
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Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
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Chronic Inflammatory Disorders and Their Redox Control: From Molecular Mechanisms to Therapeutic Opportunities
resolves10.1093/toxsci/kfn263
Oxidative Stress in Developmental Origins of Disease: Teratogenesis, Neurodevelopmental Deficits, and Cancer
resolves10.1146/annurev.pharmtox.46.120604.141046
Cell Survival Responses to Environmental Stresses Via the Keap1-Nrf2-ARE Pathway
resolves10.1074/jbc.274.37.26071
Nrf2, a Cap'n'Collar Transcription Factor, Regulates Induction of the Heme Oxygenase-1 Gene
resolves10.1016/S0021-9258(20)64358-7
Transcriptional regulation of the rat NAD(P)H:quinone reductase gene
resolves10.1042/bj3320373
Overlapping antioxidant response element and PMA responseelement sequences mediate basal and β-naphthoflavone-induced expression of the human γ-glutamylcysteine synthetase catalytic subunit gene
resolves10.1074/jbc.M113.478545
The Keap1/Nrf2 Protein Axis Plays a Role in Osteoclast Differentiation by Regulating Intracellular Reactive Oxygen Species Signaling
resolves10.1074/jbc.273.19.11783
Multivalent DNA Binding Complex Generated by Small Maf and Bach1 as a Possible Biochemical Basis for β-Globin Locus Control Region Complex
resolves10.1093/emboj/cdf516
Hemoprotein Bach1 regulates enhancer availability of heme oxygenase‐1 gene
resolves10.1093/nar/gkm638
Heme oxygenase-1 induction by NRF2 requires inactivation of the transcriptional repressor BACH1
resolves10.1089/ars.2006.8.60
Heme Oxygenase-1 Gene Enhancer Manifests Silencing Activity in a Chromatin Environment Prior to Oxidative Stress
resolves10.1074/jbc.M500166200
Bach1 Competes with Nrf2 Leading to Negative Regulation of the Antioxidant Response Element (ARE)-mediated NAD(P)H:Quinone Oxidoreductase 1 Gene Expression and Induction in Response to Antioxidants
resolves10.1016/j.freeradbiomed.2014.09.006
Nuclear Nrf2 Induction by Protein Transduction Attenuates Osteoclastogenesis
resolves10.2174/1874325001307010605
Osteoclasts Lose Innate Inflammatory Reactivity to Metal and Polymer Implant Debris Compared to Monocytes/Macrophages
resolves10.1111/j.1600-0765.2011.01352.x
Locally administered interferon-γ accelerates lipopolysaccharide-induced osteoclastogenesis independent of immunohistological RANKL upregulation
resolves10.1093/beheco/arn020
Time for some a priori thinking about post hoc testing
resolves10.1080/15216540500137669
RANKing Intracellular Signaling in Osteoclasts
resolves10.1016/j.febslet.2009.10.010
Prolonged cigarette smoke exposure decreases heme oxygenase‐1 and alters Nrf2 and Bach1 expression in human macrophages: Roles of the MAP kinases ERK<sub>1/2</sub> and JNK
resolves10.1016/j.intimp.2014.02.003
5-Aminolevulinic acid combined with ferrous iron enhances the expression of heme oxygenase-1
resolves10.1016/j.yexcr.2004.07.035
Reactive oxygen species mediate RANK signaling in osteoclasts
resolves10.3109/10428190009113378
Biology of Tartrate-Resistant Acid Phosphatase
resolves10.1177/0022034515577814
Nrf2 Activation Attenuates Both Orthodontic Tooth Movement and Relapse
resolves10.1016/j.redox.2016.01.006
Molecular regulatory mechanisms of osteoclastogenesis through cytoprotective enzymes
resolves10.1172/JCI200419657
Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation
resolves10.1002/jcb.22907
Macrophage inflammatory protein‐1α induces osteoclast formation by activation of the MEK/ERK/c‐Fos pathway and inhibition of the p38MAPK/IRF‐3/IFN‐β pathway
resolves10.1074/jbc.M510156200
MCP-1-induced Human Osteoclast-like Cells Are Tartrate-resistant Acid Phosphatase, NFATc1, and Calcitonin Receptor-positive but Require Receptor Activator of NFκB Ligand for Bone Resorption
resolves10.1016/j.cyto.2014.10.007
Osteoprotegerin induces podosome disassembly in osteoclasts through calcium, ERK, and p38 MAPK signaling pathways
resolves10.1016/j.bbrc.2008.05.048
Proteasome inhibitors induce osteoclast survival by activating the Akt pathway
resolves10.1074/jbc.M208284200
U0126 and PD98059, Specific Inhibitors of MEK, Accelerate Differentiation of RAW264.7 Cells into Osteoclast-like Cells
resolves10.1038/sj.emboj.7600248
Heme regulates gene expression by triggering Crm1‐dependent nuclear export of Bach1
resolves10.1016/j.freeradbiomed.2005.01.021
Redox regulation of the transcriptional repressor Bach1
resolves10.1074/jbc.M306764200
Cadmium Induces Nuclear Export of Bach1, a Transcriptional Repressor of Heme Oxygenase-1 Gene
resolves10.1089/ars.2006.8.107
The Heme-Bach1 Pathway in the Regulation of Oxidative Stress Response and Erythroid Differentiation
resolves10.1002/art.33497
Bach1 regulates osteoclastogenesis in a mouse model via both heme oxygenase 1–dependent and heme oxygenase 1–independent pathways
The 2 references without a DOI — listed, not checked
no DOI — not checkedAdvances in bone biology: the osteoclast
no DOI — not checkedIdentification of Nrf2regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray
What this badge says. CiteStamped means the CHECKABLE references of this work were clean at the dated check: each resolved to a known work in a public registry, and none carried a retraction notice at that time. It says nothing about the quality, findings, or importance of the work itself, and nothing about references deposited without a DOI.

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