Reference health
A common molecular logic determines embryonic stem cell self-renewal and reprogramming
65/65 checkable references clean · checked 2026-08-16
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
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The 65 checked references that resolve
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A predictive computational framework for direct reprogramming between human cell types
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Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
resolves10.1016/j.devcel.2015.10.011
Lineage-Specific Profiling Delineates the Emergence and Progression of Naive Pluripotency in Mammalian Embryogenesis
resolves10.1016/j.cell.2008.04.043
Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells
resolves10.1126/science.1248882
Defining an essential transcription factor program for naïve pluripotency
resolves10.1038/ncb2603
Nanog-dependent feedback loops regulate murine embryonic stem cell heterogeneity
resolves10.1038/nature08113
A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells
resolves10.15252/msb.20145549
Cell dynamics and gene expression control in tissue homeostasis and development
resolves10.1101/115683
Modeling signaling-dependent pluripotent cell states with boolean logic can predict cell fate transitions
resolves10.1038/npjsba.2016.10
A method to identify and analyze biological programs through automated reasoning
resolves10.1016/j.cell.2012.08.023
Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase
resolves10.1038/nature12243
High-resolution analysis with novel cell-surface markers identifies routes to iPS cells
resolves10.1016/j.cub.2013.12.040
NANOG Amplifies STAT3 Activation and They Synergistically Induce the Naive Pluripotent Program
resolves10.1002/stem.1225
Jak/Stat3 Signaling Promotes Somatic Cell Reprogramming by Epigenetic Regulation
resolves10.1371/journal.pbio.0060253
Promotion of Reprogramming to Ground State Pluripotency by Signal Inhibition
resolves10.1016/j.cell.2010.10.015
Epiblast Stem Cell Subpopulations Represent Mouse Embryos of Distinct Pregastrulation Stages
resolves10.1038/nature08592
Direct cell reprogramming is a stochastic process amenable to acceleration
resolves10.1016/j.cmet.2017.04.017
Hybrid Cellular Metabolism Coordinated by Zic3 and Esrrb Synergistically Enhances Induction of Naive Pluripotency
resolves10.1038/ncb1827
Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb
resolves10.1038/nbt1374
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
resolves10.1016/j.stem.2010.04.015
Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming
resolves10.1073/pnas.1310291110
Maturation, not initiation, is the major roadblock during reprogramming toward pluripotency from human fibroblasts
resolves10.1016/j.stem.2012.11.008
A Late Transition in Somatic Cell Reprogramming Requires Regulators Distinct from the Pluripotency Network
resolves10.1038/ncb3326
C/EBPα creates elite cells for iPSC reprogramming by upregulating Klf4 and increasing the levels of Lsd1 and Brd4
resolves10.1242/dev.030957
Klf4 reverts developmentally programmed restriction of ground state pluripotency
resolves10.1242/dev.101014
Distinct Wnt-driven primitive streak-like populations reflect <i>in vivo</i> lineage precursors
resolves10.1016/j.stem.2013.09.014
The Transcriptional and Functional Properties of Mouse Epiblast Stem Cells Resemble the Anterior Primitive Streak
resolves10.1038/nature05972
New cell lines from mouse epiblast share defining features with human embryonic stem cells
resolves10.1016/j.stem.2012.08.002
Esrrb Is a Direct Nanog Target Gene that Can Substitute for Nanog Function in Pluripotent Cells
resolves10.1016/j.stem.2012.01.020
Epiblast Stem Cell-Based System Reveals Reprogramming Synergy of Germline Factors
resolves10.1016/j.stem.2009.11.003
Oct4 and LIF/Stat3 Additively Induce Krüppel Factors to Sustain Embryonic Stem Cell Self-Renewal
resolves10.1038/emboj.2013.177
Identification of the missing pluripotency mediator downstream of leukaemia inhibitory factor
resolves10.1002/stem.709
Distinct Developmental Ground States of Epiblast Stem Cell Lines Determine Different Pluripotency Features
resolves10.1016/j.stem.2010.06.022
Stat3 Activation Is Limiting for Reprogramming to Ground State Pluripotency
resolves10.1016/j.stemcr.2015.07.014
Klf2 and Tfcp2l1, Two Wnt/β-Catenin Targets, Act Synergistically to Induce and Maintain Naive Pluripotency
resolves10.1016/j.stem.2012.06.008
Esrrb Is a Pivotal Target of the Gsk3/Tcf3 Axis Regulating Embryonic Stem Cell Self-Renewal
resolves10.1038/emboj.2013.175
Embryonic stem cell self‐renewal pathways converge on the transcription factor Tfcp2l1
resolves10.1242/dev.142711
Tracking the embryonic stem cell transition from ground state pluripotency
resolves10.1016/j.celrep.2016.05.041
Loss of the Otx2-Binding Site in the Nanog Promoter Affects the Integrity of Embryonic Stem Cell Subtypes and Specification of Inner Cell Mass-Derived Epiblast
resolves10.1038/nprot.2016.066
Visualization and cellular hierarchy inference of single-cell data using SPADE
resolves10.1038/nbt.1991
Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE
resolves10.1016/j.stem.2014.04.015
Klf2 Is an Essential Factor that Sustains Ground State Pluripotency
resolves10.1242/jcs.118273
Gbx2, a LIF/Stat3 target, promotes reprogramming to and retention of the pluripotent ground state
resolves10.1093/nar/gku895
CODEX: a next-generation sequencing experiment database for the haematopoietic and embryonic stem cell communities
resolves10.15252/embj.201592629
Stat3 promotes mitochondrial transcription and oxidative respiration during maintenance and induction of naive pluripotency
resolves10.1038/nature08797
Direct conversion of fibroblasts to functional neurons by defined factors
resolves10.1016/0092-8674(87)90585-X
Expression of a single transfected cDNA converts fibroblasts to myoblasts
resolves10.1038/nmeth.1323
Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon
resolves10.1038/nature10424
Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells
resolves10.1016/j.celrep.2016.03.073
Distinct Signaling Requirements for the Establishment of ESC Pluripotency in Late-Stage EpiSCs
The 3 references without a DOI — listed, not checked
no DOI — not checkedC/EBPα poises B cells for rapid reprogramming into induced pluripotent stem cells
no DOI — not checkedA genome-wide screen in EpiSCs identifies Nr5a nuclear receptors as potent inducers of ground state pluripotency
no DOI — not checkedDistinct developmental ground states of epiblast stem cell lines determine different pluripotency features
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