Reference health
Exploring diseases/traits and blood proteins causally related to expression of ACE2, the putative receptor of SARS-CoV-2: A Mendelian Randomization analysis highlights tentative relevance of diabetes-related traits
61/61 checkable references clean · checked 2026-07-23
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
4 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 61 checked references that resolve
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Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia
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Clinical characteristics of 2019 novel coronavirus infection in China
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
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Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus
resolves10.1038/nature02145
Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus
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A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus–induced lung injury
resolves10.1101/2020.01.22.914952
Discovery of a novel coronavirus associated with the recent pneumonia outbreak in humans and its potential bat origin
resolves10.1101/2020.02.11.944462
Cryo-EM Structure of the 2019-nCoV Spike in the Prefusion Conformation
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Susceptibility to SARS coronavirus S protein-driven infection correlates with expression of angiotensin converting enzyme 2 and infection can be blocked by soluble receptor
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ACE2 Receptor Expression and Severe Acute Respiratory Syndrome Coronavirus Infection Depend on Differentiation of Human Airway Epithelia
resolves10.1007/s11684-020-0754-0
Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection
resolves10.1158/1055-9965.EPI-19-0036
A Phenome-Wide Mendelian Randomization Study of Pancreatic Cancer Using Summary Genetic Data
resolves10.1371/journal.pmed.1002937
Genetically determined serum urate levels and cardiovascular and other diseases in UK Biobank cohort: A phenome-wide mendelian randomization study
resolves10.1093/ije/dyz182
Phenome-wide Mendelian-randomization study of genetically determined vitamin D on multiple health outcomes using the UK Biobank study
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‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*
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Mendelian randomization: genetic anchors for causal inference in epidemiological studies
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Clustered Environments and Randomized Genes: A Fundamental Distinction between Conventional and Genetic Epidemiology
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Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease
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A two-stage model in a Bayesian framework to estimate a survival endpoint in the presence of confounding by indication
resolves10.1534/genetics.117.300360
Transformation of Summary Statistics from Linear Mixed Model Association on All-or-None Traits to Odds Ratio
resolves10.1038/s41588-018-0154-4
Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation
resolves10.1002/gepi.21758
Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data
resolves10.1093/ije/dyv080
Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression
resolves10.1038/s41467-017-02317-2
Causal associations between risk factors and common diseases inferred from GWAS summary data
resolves10.1038/s41588-018-0241-6
Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps
resolves10.32614/CRAN.package.mr.raps
mr.raps: Two Sample Mendelian Randomization using Robust Adjusted Profile Score
resolves10.1093/hmg/ddy163
Evaluating the potential role of pleiotropy in Mendelian randomization studies
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Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases
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ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks
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The control of the false discovery rate in multiple testing under dependency
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False Discovery Rate Regression: An Application to Neural Synchrony Detection in Primary Visual Cortex
resolves10.1007/s10654-018-0424-6
Mendelian randomization with a binary exposure variable: interpretation and presentation of causal estimates
resolves10.1038/ng.2897
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
resolves10.1016/S2213-8587(17)30362-5
Frequency and phenotype of type 1 diabetes in the first six decades of life: a cross-sectional, genetically stratified survival analysis from UK Biobank
resolves10.1002/sim.7221
A framework for the investigation of pleiotropy in two‐sample summary data Mendelian randomization
resolves10.1183/13993003.00547-2020
Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis
resolves10.1007/s12250-015-3679-z
Risk factors for severity and mortality in patients with MERS-CoV: Analysis of publicly available data from Saudi Arabia
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Prevalence of comorbidities in cases of Middle East respiratory syndrome coronavirus: a retrospective study
resolves10.1172/jci.insight.131774
Comorbid diabetes results in immune dysregulation and enhanced disease severity following MERS-CoV infection
resolves10.1016/S1470-2045(20)30096-6
Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China
resolves10.1016/j.cell.2020.04.004
Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2
resolves10.1101/2020.03.22.002386
A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing
resolves10.1038/s41440-020-0433-1
Antihypertensive treatment with ACEI/ARB of patients with COVID-19 complicated by hypertension
resolves10.1161/JAHA.120.016509
Coronavirus Disease 2019 (COVID‐19): Do Angiotensin‐Converting Enzyme Inhibitors/Angiotensin Receptor Blockers Have a Biphasic Effect?
resolves10.1161/CIRCULATIONAHA.104.510461
Effect of Angiotensin-Converting Enzyme Inhibition and Angiotensin II Receptor Blockers on Cardiac Angiotensin-Converting Enzyme 2
resolves10.1152/ajprenal.00110.2010
The ANG-(1–7)/ACE2/mas axis in the regulation of nephron function
resolves10.1152/ajpheart.00068.2005
Angiotensin II AT<sub>1</sub> receptors regulate ACE2 and angiotensin-(1–7) expression in the aorta of spontaneously hypertensive rats
resolves10.1007/s00726-014-1889-6
Human intestine luminal ACE2 and amino acid transporter expression increased by ACE-inhibitors
resolves10.1016/S0140-6736(20)30304-4
Baricitinib as potential treatment for 2019-nCoV acute respiratory disease
resolves10.1002/prp2.175
In vitro pharmacological profiling of R406 identifies molecular targets underlying the clinical effects of fostamatinib
resolves10.3389/fphar.2019.00897
Efficacy and Safety of Multiple Dosages of Fostamatinib in Adult Patients With Rheumatoid Arthritis: A Systematic Review and Meta-Analysis
resolves10.1093/ije/dyp391
Zinc supplementation for the prevention of acute lower respiratory infection in children in developing countries: meta-analysis and meta-regression of randomized trials
resolves10.1371/journal.ppat.1001176
Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture
resolves10.3892/ijmm.2020.4575
Zinc and respiratory tract infections: Perspectives for COVID‑19 (Review)
resolves10.1002/gepi.20589
The use of phenome-wide association studies (PheWAS) for exploration of novel genotype-phenotype relationships and pleiotropy discovery
The 4 references without a DOI — listed, not checked
no DOI — not checkedThe epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China
no DOI — not checked2021011110454760000_2020.03.04.20031237v2.36
no DOI — not checkedRecombinant Human Angiotensin-converting Enzyme 2 (rhACE2) as a Treatment for Patients With COVID-19. Available at https://ClinicalTrials.gov/show/NCT04335136., 2020
no DOI — not checkedConcentration-dependent effects of zinc on angiotensin-converting enzyme-2 activity (1067.4)
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