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Synergistic effect of ibrutinib and CD19 CAR‐T cells on Raji cells in vivo and in vitro

https://doi.org/10.1111/cas.14638
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Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

The 32 checked references that resolve
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Ibrutinib downregulates a subset of miRNA leading to upregulation of tumor suppressors and inhibition of cell proliferation in chronic lymphocytic leukemia
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Egress of CD19+CD5+ cells into peripheral blood following treatment with the Bruton tyrosine kinase inhibitor ibrutinib in mantle cell lymphoma patients
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BTK inhibition targets in vivo CLL proliferation through its effects on B-cell receptor signaling activity
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The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo
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Dual Phosphorylation of Btk by Akt/Protein Kinase B Provides Docking for 14-3-3ζ, Regulates Shuttling, and Attenuates both Tonic and Induced Signaling in B Cells
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Bruton's Tyrosine Kinase: From X-Linked Agammaglobulinemia Toward Targeted Therapy for B-Cell Malignancies
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Bruton Tyrosine Kinase Inhibitor Ibrutinib (PCI-32765) Has Significant Activity in Patients With Relapsed/Refractory B-Cell Malignancies
resolves10.1182/blood-2014-02-548610
Ibrutinib inhibits BCR and NF-κB signaling and reduces tumor proliferation in tissue-resident cells of patients with CLL
resolves10.1056/NEJMoa1215637
Targeting BTK with Ibrutinib in Relapsed Chronic Lymphocytic Leukemia
resolves10.1056/NEJMoa1306220
Targeting BTK with Ibrutinib in Relapsed or Refractory Mantle-Cell Lymphoma
resolves10.1038/s41375-018-0023-2
Ibrutinib versus temsirolimus: 3-year follow-up of patients with previously treated mantle cell lymphoma from the phase 3, international, randomized, open-label RAY study
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Bruton Tyrosine Kinase (BTK) and Its Role in B-cell Malignancy
resolves10.1038/leu.2016.157
Clinical response to ibrutinib is accompanied by normalization of the T-cell environment in CLL-related autoimmune cytopenia
resolves10.1182/blood-2014-09-603670
Outcomes of patients with chronic lymphocytic leukemia after discontinuing ibrutinib
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Etiology of Ibrutinib Therapy Discontinuation and Outcomes in Patients With Chronic Lymphocytic Leukemia
resolves10.1056/NEJMoa1707447
Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma
resolves10.1056/NEJMoa1804980
Tisagenlecleucel in Adult Relapsed or Refractory Diffuse Large B-Cell Lymphoma
resolves10.1056/NEJMoa1709866
Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia
resolves10.1056/NEJMoa1103849
Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia
resolves10.1126/scitranslmed.aac5415
Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia
resolves10.1200/JCO.2017.72.8519
Durable Molecular Remissions in Chronic Lymphocytic Leukemia Treated With CD19-Specific Chimeric Antigen Receptor–Modified T Cells After Failure of Ibrutinib
resolves10.1158/1078-0432.CCR-15-1527
The Addition of the BTK Inhibitor Ibrutinib to Anti-CD19 Chimeric Antigen Receptor T Cells (CART19) Improves Responses against Mantle Cell Lymphoma
resolves10.1186/s40425-019-0686-x
State-of-the-art for CAR T-cell therapy for chronic lymphocytic leukemia in 2019
resolves10.1038/s41591-018-0010-1
Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia
resolves10.1182/blood-2017-06-786129
Cellular kinetics of CTL019 in relapsed/refractory B-cell acute lymphoblastic leukemia and chronic lymphocytic leukemia
resolves10.1182/blood-2015-11-679134
Ibrutinib enhances chimeric antigen receptor T-cell engraftment and efficacy in leukemia
resolves10.1172/JCI89756
Ibrutinib treatment improves T cell number and function in CLL patients
resolves10.1182/blood-2012-08-452607
Coming full circle: 70 years of chronic lymphocytic leukemia cell redistribution, from glucocorticoids to inhibitors of B-cell receptor signaling
resolves10.1016/S1470-2045(14)70335-3
Safety and activity of ibrutinib plus rituximab for patients with high-risk chronic lymphocytic leukaemia: a single-arm, phase 2 study
resolves10.1038/leu.2017.304
Ibrutinib modulates the immunosuppressive CLL microenvironment through STAT3-mediated suppression of regulatory B-cell function and inhibition of the PD-1/PD-L1 pathway
resolves10.1182/blood-2013-06-507947
Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes
resolves10.4049/jimmunol.1601190
Ibrutinib Therapy Increases T Cell Repertoire Diversity in Patients with Chronic Lymphocytic Leukemia
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