Reference health
Tertiary lymphoid structures, drivers of the anti‐tumor responses in human cancers
1 of 136 checkable references need attention · checked 2026-07-23
At the dated check, the references listed below either did not resolve in Crossref or DataCite, or carried a retraction notice. Each one is shown with the registry record that put it there.
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References needing attention
does not resolve to a known work10.1136/jclinpath‐2015‐203089.
The 135 checked references that resolve
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Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome
resolves10.1056/NEJMoa051424
Effector Memory T Cells, Early Metastasis, and Survival in Colorectal Cancer
resolves10.1158/1078-0432.CCR-14-2926
Orchestration and Prognostic Significance of Immune Checkpoints in the Microenvironment of Primary and Metastatic Renal Cell Cancer
resolves10.1158/1078-0432.CCR-12-3847
Characteristics and Clinical Impacts of the Immune Environments in Colorectal and Renal Cell Carcinoma Lung Metastases: Influence of Tumor Origin
resolves10.1200/JCO.2007.15.0284
Long-Term Survival for Patients With Non–Small-Cell Lung Cancer With Intratumoral Lymphoid Structures
resolves10.1073/pnas.0507223102
Lymphoid neogenesis in chronic rejection: Evidence for a local humoral alloimmune response
resolves10.1371/journal.pone.0011398
Immune Responses Elicited in Tertiary Lymphoid Tissues Display Distinctive Features
resolves10.1038/ki.2011.317
A stepwise breakdown of B-cell tolerance occurs within renal allografts during chronic rejection
resolves10.1111/j.0105-2896.2009.00861.x
Secondary and ectopic lymphoid tissue responses in rheumatoid arthritis: from inflammation to autoimmunity and tissue damage/remodeling
resolves10.1161/CIRCULATIONAHA.114.010988
Control of the T Follicular Helper–Germinal Center B-Cell Axis by CD8
<sup>+</sup>
Regulatory T Cells Limits Atherosclerosis and Tertiary Lymphoid Organ Development
resolves10.1007/s00428-015-1787-7
The immune response in cancer: from immunology to pathology to immunotherapy
resolves10.1038/ni.3290
Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma
resolves10.1158/2326-6066.CIR-14-0027
Immunotherapy Converts Nonimmunogenic Pancreatic Tumors into Immunogenic Foci of Immune Regulation
resolves10.1126/scitranslmed.3007323
Intramuscular Therapeutic Vaccination Targeting HPV16 Induces T Cell Responses That Localize in Mucosal Lesions
resolves10.1038/nm1091
Role of inducible bronchus associated lymphoid tissue (iBALT) in respiratory immunity
resolves10.1073/pnas.0700591104
Pulmonary expression of CXC chemokine ligand 13, CC chemokine ligand 19, and CC chemokine ligand 21 is essential for local immunity to influenza
resolves10.1158/0008-5472.CAN-13-1342
Dendritic Cells in Tumor-Associated Tertiary Lymphoid Structures Signal a Th1 Cytotoxic Immune Contexture and License the Positive Prognostic Value of Infiltrating CD8+ T Cells
resolves10.1164/rccm.201309-1611OC
Presence of B Cells in Tertiary Lymphoid Structures Is Associated with a Protective Immunity in Patients with Lung Cancer
resolves10.1158/0008-5472.CAN-11-0952
Characterization of Chemokines and Adhesion Molecules Associated with T cell Presence in Tertiary Lymphoid Structures in Human Lung Cancer
resolves10.1084/jem.20061890
In vivo imaging of cytotoxic T cell infiltration and elimination of a solid tumor
resolves10.1158/0008-5472.CAN-03-1957
Microvessel Density as a Prognostic Factor in Women with Breast Cancer
resolves10.1038/sj.bjc.6603176
Microvessel density and VEGF expression are prognostic factors in colorectal cancer. Meta-analysis of the literature
resolves10.1158/1078-0432.CCR-07-0414
Inverse Prognostic Impact of Angiogenic Marker Expression in Tumor Cells versus Stromal Cells in Non–Small Cell Lung Cancer
resolves10.1016/j.ejca.2008.03.012
The clinical significance of lymphangiogenesis and angiogenesis in non-small cell lung cancer patients
resolves10.1136/jcp.2003.013508
Prognostic impact of VEGF, CD31, CD34, and CD105 expression and tumour vessel invasion after radical surgery for IB–IIA non-small cell lung cancer
resolves10.1158/0008-5472.CAN-11-0431
Human Solid Tumors Contain High Endothelial Venules: Association with T- and B-Lymphocyte Infiltration and Favorable Prognosis in Breast Cancer
resolves10.1084/jem.20090410
Dendritic cells are crucial for maintenance of tertiary lymphoid structures in the lung of influenza virus–infected mice
resolves10.1084/jem.20091472
Induced bronchus-associated lymphoid tissue serves as a general priming site for T cells and is maintained by dendritic cells
resolves10.1016/S1074-7613(00)80615-9
A Novel Lysosome-Associated Membrane Glycoprotein, DC-LAMP, Induced upon DC Maturation, Is Transiently Expressed in MHC Class II Compartment
resolves10.1016/j.immuni.2015.08.006
Regulatory T Cells in Tumor-Associated Tertiary Lymphoid Structures Suppress Anti-tumor T Cell Responses
resolves10.1158/0008-5472.CAN-08-2360
Regulatory T Cells Recruited through CCL22/CCR4 Are Selectively Activated in Lymphoid Infiltrates Surrounding Primary Breast Tumors and Lead to an Adverse Clinical Outcome
resolves10.1016/j.immuni.2013.10.003
Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer
resolves10.1080/2162402X.2015.1051922
A high density of tertiary lymphoid structure B cells in lung tumors is associated with increased CD4<sup>+</sup>T cell receptor repertoire clonality
resolves10.1159/000474780
Changes on Distribution of CD4+/ CD45RA- and CD87CD1Y Cells in Tumor-Infiltrating Lymphocytes of Renal Cell Carcinoma Associated with Tumor Progression
resolves10.1038/bjc.2011.368
Prognostic significance of CD45RO+ memory T cells in renal cell carcinoma
resolves10.1111/j.1399-0039.2006.00673.x
Analysis of the expression of HLA class I, proinflammatory cytokines and chemokines in primary tumors from patients with localized and metastatic renal cell carcinoma
resolves10.1016/j.juro.2011.06.049
Role of Inflammatory Related Gene Expression in Clear Cell Renal Cell Carcinoma Development and Clinical Outcomes
resolves10.1371/journal.pone.0076746
Meta-Analysis Identifies NF-κB as a Therapeutic Target in Renal Cancer
resolves10.1002/cncr.20747
Up‐regulation of the interferon γ (IFN‐γ)‐inducible chemokines IFN‐inducible T‐cell α chemoattractant and monokine induced by IFN‐γ and of their receptor CXC receptor 3 in human renal cell carcinoma
resolves10.1016/j.eururo.2011.10.035
T Lymphocyte Recruitment into Renal Cell Carcinoma Tissue: A Role for Chemokine Receptors CXCR3, CXCR6, CCR5, and CCR6
resolves10.1158/1078-0432.CCR-13-1631
The Effect of VEGF-Targeted Therapy on Biomarker Expression in Sequential Tissue from Patients with Metastatic Clear Cell Renal Cancer
resolves10.1111/bju.12068
Regulatory
<scp>T</scp>
cells, interleukin (
<scp>IL</scp>
)‐6,
<scp>IL</scp>
‐8,
<scp>V</scp>
ascular endothelial growth factor (
<scp>VEGF</scp>
),
<scp>CXC</scp>
L10,
<scp>CXC</scp>
L11, epidermal growth factor (
<scp>EGF</scp>
) and hepatocyte growth factor (
<scp>HGF</scp>
) as surrogate markers of host immunity in patients with renal cell carcinoma
resolves10.1158/1078-0432.CCR-14-1128
Molecular Subtypes of Clear Cell Renal Cell Carcinoma Are Associated with Sunitinib Response in the Metastatic Setting
resolves10.1158/0008-5472.CAN-09-0852
Simultaneous Infiltration of Polyfunctional Effector and Suppressor T Cells into Renal Cell Carcinomas
resolves10.1158/0008-5472.CAN-12-0588
Distinctive Features of the Differentiated Phenotype and Infiltration of Tumor-Reactive Lymphocytes in Clear Cell Renal Cell Carcinoma
resolves10.1182/blood.V92.12.4778
Inhibition of the Differentiation of Dendritic Cells From CD34+ Progenitors by Tumor Cells: Role of Interleukin-6 and Macrophage Colony-Stimulating Factor
resolves10.1016/j.molimm.2008.09.015
Dysfunctional DC subsets in RCC patients: Ex vivo correction to yield an effective anti-cancer vaccine
resolves10.1016/j.ajpath.2011.03.011
Human Renal Cell Carcinoma Induces a Dendritic Cell Subset That Uses T-Cell Crosstalk for Tumor-Permissive Milieu Alterations
resolves10.1111/j.1365-2249.2006.03212.x
Interleukin-6 and vascular endothelial growth factor release by renal cell carcinoma cells impedes lymphocyte–dendritic cell cross-talk
resolves10.1007/s00120-004-0599-1
Human renal cell carcinoma inhibits dendritic cell maturation and functions
resolves10.1097/01.ju.0000127726.25609.87
HIGH EXPRESSION OF CHEMOKINE GENE AS A FAVORABLE PROGNOSTIC FACTOR IN RENAL CELL CARCINOMA
resolves10.1158/0008-5472.CAN-07-6122
Macrophage Inflammatory Protein–1δ: A Novel Osteoclast Stimulating Factor Secreted by Renal Cell Carcinoma Bone Metastasis
resolves10.1007/s00262-006-0122-1
IL-4 inhibits the TNF-α induced proliferation of renal cell carcinoma (RCC) and cooperates with TNF-α to induce apoptotic and cytokine responses by RCC: implications for antitumor immune responses
resolves10.14712/fb2008054040134
Determination of Angiogenic Factors in Serum by Protein Array in Patients with Renal Cell Carcinoma
resolves10.1002/ijc.25981
Osteoblast‐secreted factors enhance the expression of dysadherin and CCL2‐dependent migration of renal carcinoma cells
resolves10.1038/onc.2010.260
The unexpected role of lymphotoxin β receptor signaling in carcinogenesis: from lymphoid tissue formation to liver and prostate cancer development
resolves10.1038/nature10540
Dendritic cells control lymphocyte entry to lymph nodes through high endothelial venules
resolves10.1158/0008-5472.CAN-06-0217
Targeting the Lymphotoxin-β Receptor with Agonist Antibodies as a Potential Cancer Therapy
resolves10.4049/jimmunol.0804324
Secondary Lymphoid Organs: Responding to Genetic and Environmental Cues in Ontogeny and the Immune Response
resolves10.1038/nrd3705
Bench to bedside: elucidation of the OPG–RANK–RANKL pathway and the development of denosumab
resolves10.1016/j.jaci.2003.08.039
IL-21: a novel IL-2–family lymphokine that modulates B, T, and natural killer cell responses
resolves10.1038/ni.2925
The transcription factor IRF1 dictates the IL-21-dependent anticancer functions of TH9 cells
resolves10.1016/j.it.2008.02.008
Interleukin-21: a critical regulator of the balance between effector and regulatory T-cell responses
resolves10.1002/art.38735
Interleukin‐21 Promotes Germinal Center Reaction by Skewing the Follicular Regulatory T Cell to Follicular Helper T Cell Balance in Autoimmune BXD2 Mice
resolves10.1084/jem.20091777
IL-21 regulates germinal center B cell differentiation and proliferation through a B cell–intrinsic mechanism
resolves10.1016/j.immuni.2008.06.001
A Fundamental Role for Interleukin-21 in the Generation of T Follicular Helper Cells
resolves10.1074/jbc.M110.101444
Rational Design of Interleukin-21 Antagonist through Selective Elimination of the γC Binding Epitope
resolves10.1038/ni947
Costimulation through the inducible costimulator ligand is essential for both T helper and B cell functions in T cell–dependent B cell responses
resolves10.1016/j.coi.2010.01.001
Regulation of CD4 T cell activation and effector function by inducible costimulator (ICOS)
resolves10.4049/jimmunol.1103581
ICOS Mediates the Generation and Function of CD4+CD25+Foxp3+ Regulatory T Cells Conveying Respiratory Tolerance
resolves10.1158/0008-5472.CAN-10-1379
Melanoma Cells Express ICOS Ligand to Promote the Activation and Expansion of T-Regulatory Cells
resolves10.1158/0008-5472.CAN-12-2409
ICOS-Ligand Expression on Plasmacytoid Dendritic Cells Supports Breast Cancer Progression by Promoting the Accumulation of Immunosuppressive CD4+ T Cells
resolves10.1158/0008-5472.CAN-12-2271
Plasmacytoid Dendritic Cells Promote Immunosuppression in Ovarian Cancer via ICOS Costimulation of Foxp3+ T-Regulatory Cells
resolves10.4161/onci.23887
Plasmacytoid dendritic cells and regulatory T cells in the tumor microenvironment
resolves10.4049/jimmunol.0901647
The IL-7 Signaling Pathway Regulates Lymph Node Development Independent of Peripheral Lymphocytes
resolves10.1016/j.immuni.2007.04.009
Ectopic Lymphoid-Organ Development Occurs through Interleukin 7-Mediated Enhanced Survival of Lymphoid-Tissue-Inducer Cells
resolves10.1128/JVI.00534-14
Crucial Roles of Interleukin-7 in the Development of T Follicular Helper Cells and in the Induction of Humoral Immunity
resolves10.1073/pnas.1203795109
Anti–IL-7 receptor-α reverses established type 1 diabetes in nonobese diabetic mice by modulating effector T-cell function
resolves10.1038/ng2103
Interleukin 7 receptor α chain ( IL7R ) shows allelic and functional association with multiple sclerosis
resolves10.1158/1078-0432.CCR-13-1016
Interleukin-7 Mediates Selective Expansion of Tumor-redirected Cytotoxic T Lymphocytes (CTLs) without Enhancement of Regulatory T-cell Inhibition
resolves10.1371/journal.pone.0113314
Interleukin-7 Optimizes FOXP3+CD4+ Regulatory T Cells Reactivity to Interleukin-2 by Modulating CD25 Expression
resolves10.1371/journal.pone.0036596
Interleukin-7 Influences FOXP3+CD4+ Regulatory T Cells Peripheral Homeostasis
resolves10.4049/jimmunol.1203547
IL-7 Modulates In Vitro and In Vivo Human Memory T Regulatory Cell Functions through the CD39/ATP Axis
resolves10.4049/jimmunol.1201286
IL-7 Abrogates Suppressive Activity of Human CD4+CD25+FOXP3+ Regulatory T Cells and Allows Expansion of Alloreactive and Autoreactive T Cells
resolves10.4049/jimmunol.168.3.1001
Ectopic Expression of the Murine Chemokines CCL21a and CCL21b Induces the Formation of Lymph Node-Like Structures in Pancreas, But Not Skin, of Transgenic Mice
resolves10.4049/jimmunol.164.8.3955
Cutting Edge: Ectopic Expression of the Chemokine TCA4/SLC Is Sufficient to Trigger Lymphoid Neogenesis
resolves10.1038/ni.1789
Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation
resolves10.1084/jem.190.8.1183
The Reduced Expression of 6ckine in the <i>plt</i> Mouse Results from the Deletion of One of Two 6ckine Genes
resolves10.1111/eci.12063
Effects of <scp>CXCL</scp>13 inhibition on lymphoid follicles in models of autoimmune disease
resolves10.1074/jbc.M405808200
Inhibition of Generation of Cytotoxic T Lymphocyte Activity by a CCL19/Macrophage Inflammatory Protein (MIP)-3β Antagonist
resolves10.1177/0194599814533775
A Cytokine‐Delivering Polymer Is Effective in Reducing Tumor Burden in a Head and Neck Squamous Cell Carcinoma Murine Model
resolves10.1128/JVI.00208-07
Local Expression of Secondary Lymphoid Tissue Chemokine Delivered by Adeno-Associated Virus within the Tumor Bed Stimulates Strong Anti-Liver Tumor Immunity
resolves10.1677/joe.1.06688
Expression and function of the chemokine receptor CCR7 in thyroid carcinomas
resolves10.1186/1756-8722-6-89
Anti-CCR7 therapy exerts a potent anti-tumor activity in a xenograft model of human mantle cell lymphoma
resolves10.1016/j.ajpath.2011.04.012
Manifestation of Spontaneous and Early Autoimmune Gastritis in CCR7-Deficient Mice
resolves10.1016/S0002-9440(10)63631-0
Molecular Characterization of NF-HEV, a Nuclear Factor Preferentially Expressed in Human High Endothelial Venules
resolves10.1038/onc.2014.418
Interleukin-33/ST2 axis promotes epithelial cell transformation and breast tumorigenesis via upregulation of COT activity
resolves10.1158/1538-7445.AM2015-5069
Abstract 5069: IL-33 secreted by cancer-associated fibroblasts mediates epithelial-stromal interactions and promotes gastric cancer invasion via ERK signaling pathway
resolves10.1093/jnci/86.11.829
Dangers of Using "Optimal" Cutpoints in the Evaluation of Prognostic Factors
resolves10.4161/onci.26470
Regulation of tumor-associated high-endothelial venules by dendritic cells
resolves10.1002/ijc.28533
Characteristics and significance of colorectal cancer associated lymphoid reaction
resolves10.1111/j.1365-2249.2010.04147.x
Survival in rectal cancer is predicted by T cell infiltration of tumour-associated lymphoid nodules
resolves10.1158/1078-0432.CCR-13-2590
Occurrence of Tertiary Lymphoid Tissue Is Associated with T-Cell Infiltration and Predicts Better Prognosis in Early-Stage Colorectal Cancers
resolves10.1016/j.ajpath.2011.03.007
Unique Ectopic Lymph Node-Like Structures Present in Human Primary Colorectal Carcinoma Are Identified by Immune Gene Array Profiling
resolves10.1080/2162402X.2015.1054598
Tumor infiltration by Tbet+ effector T cells and CD20+ B cells is associated with survival in gastric cancer patients
resolves10.1007/s00262-007-0286-3
Density of DC-LAMP+ mature dendritic cells in combination with activated T lymphocytes infiltrating primary cutaneous melanoma is a strong independent prognostic factor
resolves10.1038/srep00765
12-Chemokine Gene Signature Identifies Lymph Node-like Structures in Melanoma: Potential for Patient Selection for Immunotherapy?
resolves10.1186/1472-6890-14-38
Characterisation and prognostic value of tertiary lymphoid structures in oral squamous cell carcinoma
resolves10.1038/bjc.2015.145
Intratumoral tertiary lymphoid organ is a favourable prognosticator in patients with pancreatic cancer
resolves10.1371/journal.pone.0099008
B Cells and Ectopic Follicular Structures: Novel Players in Anti-Tumor Programming with Prognostic Power for Patients with Metastatic Colorectal Cancer
The 4 references without a DOI — listed, not checked
no DOI — not checkedProliferative activity of intratumoral CD8(+) T‐lymphocytes as a prognostic factor in human renal cell carcinoma: clinicopathologic demonstration of antitumor immunity
no DOI — not checkedMinimal recruitment and activation of dendritic cells within renal cell carcinoma
no DOI — not checkedCharacterization of the response of dendritic cells and regulatory T cells to tumor antigens in patients with renal cell carcinoma
no DOI — not checkedPrognostic value of immune cell infiltration, tertiary lymphoid structures and PD‐L1 expression in Merkel cell carcinomas
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