Reference health
Metabolic basis of benzene toxicity
65/65 checkable references clean · checked 2026-07-23
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
17 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 65 checked references that resolve
resolves10.1001/jama.1963.03060100028011
Benzene Exposure and Aplastic Anemia Followed by Leukemia 15 Years Later
resolves10.1042/bj0550337
Studies in detoxication. 54. The metabolism of benzene. (<i>a</i>) The formation of phenylglucuronide and phenylsulphuric acid from [14C]benzene. (<i>b</i>) The metabolism of [14C]phenol
resolves10.1093/carcin/16.7.1519
<i>In vitro</i> conjugation of benzene metabolites by human liver: potential influence of interindividual variability on benzene toxicity
resolves10.1016/S0022-3565(25)20879-5
Identification and induction of cytochromes P450, P450IIE1 and P450IA1 in rabbit bone marrow.
resolves10.1006/faat.1994.1052
Absence of Detectable P450 2E1 in Bone Marrow of B6C3F1 Mice: Relevance to Butadiene-Induced Bone Marrow Toxicity
resolves10.1016/0304-3835(87)90105-4
The metabolism in vitro of 7,12-dimethylbenz[a]-anthracene by human bone marrow
resolves10.1289/ehp.898223
Peroxidase-dependent metabolism of benzene's phenolic metabolites and its potential role in benzene toxicity and carcinogenicity.
resolves10.1084/jem.134.4.907
THE DEVELOPMENT OF NEUTROPHILIC POLYMORPHONUCLEAR LEUKOCYTES IN HUMAN BONE MARROW
resolves10.1016/0041-008X(88)90025-7
Oxidation of catechol by horseradish peroxidase and human leukocyte peroxidase: Reactions of o-benzoquinone and o-benzosemiquinone*1
resolves10.1016/0891-5849(91)90063-9
Potential role of free radicals in benzene-induced myelotoxicity and leukemia
resolves10.1016/S0026-895X(25)09266-1
Cell-specific metabolism in mouse bone marrow stroma: studies of activation and detoxification of benzene metabolites.
resolves10.1016/S0090-9556(25)08768-9
Stimulation of in vitro bioactivation of hydroquinone by phenol in bone marrow cells.
resolves10.1093/carcin/14.11.2329
Peroxidase activation of hydroquinone results in the formation of DNA adducts in HL-60 cells, mouse bone marrow macrophages and human bone marrow
resolves10.1016/0041-008X(87)90157-8
Suppression of bone marrow stromal cell function by benzene and hydroquinone is ameliorated by indomethacin
resolves10.1016/0014-5793(81)80320-1
Human eosinophil peroxidase: a novel isolation procedure, spectral properties and chlorinating activity
resolves10.1016/0041-008X(81)90462-2
Toxic effects of benzene and benzene metabolites on granulopoietic stem cells and bone marrow cellularity in mice
resolves10.1016/0041-008X(87)90196-7
An interaction of benzene metabolites reproduces the myelotoxicity observed with benzene exposure
resolves10.1016/0300-483X(90)90035-F
Phenol-induced stimulation of hydroquinone bioactivation in mouse bone marrow in vivo: possible implications in benzene myelotoxicity
resolves10.1016/0027-5107(91)90147-G
Two benzene metabolites, catechol and hydroquinone, produce a synergistic induction of micronuclei and toxicity in cultured human lymphocytes
resolves10.1073/pnas.83.21.8356
Formation of muconaldehyde, an open-ring metabolite of benzene, in mouse liver microsomes: an additional pathway for toxic metabolites.
resolves10.1016/0041-008X(92)90107-4
Metabolism of trans, trans-muconaldehyde by aldehyde and alcohol dehydrogenases: Identification of a novel metabolite
resolves10.1021/tx00034a029
Reaction of (E,E)-muconaldehyde and its aldehydic metabolites, (E,E)-6-oxohexadienoic acid and (E,E)-6-hydroxyhexa-2,4-dienal, with glutathione
resolves10.1007/BF01969916
Pathways of trans,trans-muconaldehyde metabolism in mouse liver cytosol: Reversibility of monoreductive metabolism and formation of end products
resolves10.1016/0891-5849(94)00148-D
Studies on pathways of ring opening of benzene in a Fenton system
resolves10.2307/3430769
Multiple-Site Carcinogenicity of Benzene in Fischer 344 Rats and B6C3F 1 Mice
resolves10.1016/0304-3835(80)90006-3
Peroxidase activity in the rat Zymbal gland and its possible role in the metabolic activation of aminostilbenes in the target tissue
resolves10.1016/0167-4838(92)90265-F
Purification and characterization of a soluble peroxidase of rat preputial gland: comparison with lactoperoxidase
resolves10.1016/0040-8166(82)90013-1
Harderian glands in mice: Fluorescence, peroxidase activity and fine structure
resolves10.1016/S0026-895X(25)15064-5
DT-diaphorase and peroxidase influence the covalent binding of the metabolites of phenol, the major metabolite of benzene.
resolves10.1016/0304-4173(86)90005-4
The O2−-forming NADPH oxidase of the phagocytes: nature, mechanisms of activation and function
resolves10.1182/blood.V54.2.429.429
Development of Oxidase activity by human bone marrow granulocytes
resolves10.1182/blood.V72.1.273.273
An analysis of the multilineage production of human hematopoietic progenitors in long-term bone marrow culture: evidence that reactive oxygen intermediates derived from mature phagocytic cells have a role in limiting progenitor cell self-renewal
resolves10.1007/978-1-4757-0674-1_13
Relationship between Benzene Metabolism and Toxicity: A Proposed Mechanism for the Formation of Reactive Intermediates from Polyphenol Metabolites
resolves10.1016/0009-2797(91)90022-Y
Effects of superoxide dismutase on the autoxidation of 1,4-hydroquinone
resolves10.1016/0041-008X(84)90027-9
In vitro effects of benzene metabolites on mouse bone marrow stromal cells
resolves10.1073/pnas.87.9.3584
Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers.
resolves10.1016/S0022-3565(25)22249-2
Bone marrow stromal cell regulation of B-lymphopoiesis. II. Mechanisms of hydroquinone inhibition of pre-B cell maturation.
resolves10.1016/0041-008X(89)90249-4
Macrophage regulation of myelopoiesis is altered by exposure to the benzene metabolite hydroquinone
resolves10.1016/S0026-895X(25)09971-7
Bone marrow stromal cell bioactivation and detoxification of the benzene metabolite hydroquinone: comparison of macrophages and fibroblastoid cells.
resolves10.1016/0041-008X(92)90197-Z
Induction of quinone reductase and glutathione in bone marrow cells by 1,2-dithiole-3-thione: Effect on hydroquinone-induced cytotoxicity
resolves10.2307/3431427
Studies with 1,2-Dithiole-3-Thione As a Chemoprotector of Hydroquinone-Induced Toxicity to DBA/2-Derived Bone Marrow Stromal Cells
resolves10.1182/blood.V78.4.938.938
Role for interleukin-1 (IL-1) in benzene-induced hematotoxicity: inhibition of conversion of pre-IL-1 alpha to mature cytokine in murine macrophages by hydroquinone and prevention of benzene-induced hematotoxicity in mice by IL-1 alpha
resolves10.1016/0378-4274(94)90096-5
Decreased content of the IL1α processing enzyme calpain in murine bone marrow-derived macrophages after treatment with the benzene metabolite hydroquinone
resolves10.1073/pnas.87.14.5548
Identification of calcium-activated neutral protease as a processing enzyme of human interleukin 1 alpha.
resolves10.1182/blood.V82.5.1599.1599
Myeloperoxidase: expression and modulation in a large panel of human leukemia-lymphoma cell lines
resolves10.1016/S0026-895X(25)09689-0
Peroxidase activity in murine and human hematopoietic progenitor cells: potential relevance to benzene-induced toxicity.
resolves10.1182/blood.V82.7.2069.bloodjournal8272069
Myeloperoxidase expression in CD34+ normal human hematopoietic cells
resolves10.1016/0092-8674(93)90462-Y
Suppression of apoptosis allows differentiation and development of a multipotent hemopoietic cell line in the absence of added growth factors
resolves10.1002/mc.2940110109
bcl‐2 delay of alkylating agent‐induced apoptotic death in a murine hemopoietic stem cell line
resolves10.1097/00008571-199508000-00003
Identification of an NAD(P)H:quinone oxidoreductase polymorphism and its association with lung cancer and smoking
resolves10.1093/carcin/15.2.219
Expression of NAD(P)H: quinone oxidoreductase and glutathione S-transferases α and π in human renal cell carcinoma and in kidney cancer-derived cell lines
resolves10.1515/bchm3.1994.375.7.439
Loss of Heterozygosity at the NAD(P)H:Quinone Oxidoreductase Locus Associated with Increased Resistance against Mitomycin C in a Human Bladder Carcinoma Cell Line
resolves10.1073/pnas.77.9.5216
Increase of NAD(P)H:quinone reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity.
resolves10.1016/0065-2571(82)90021-8
Elevation of quinone reductase activity by anticarcinogenic antioxidants
resolves10.1093/carcin/12.7.1175
DT-diaphorase activity and mitomycin C sensitivity in non-transformed cell strains derived from members of a cancer-prone family
resolves10.1016/0006-2952(91)90108-H
Studies on the mechanism of resistance to mitomycin C and porfiromycin in a human cell strain derived from a cancer-prone individual
resolves10.1016/0006-2952(93)90279-6
Carbamazepine metabolism to a reactive intermediate by the myeloperoxidase system of activated neutrophils
resolves10.1016/0140-6736(92)91877-B
Antimyeloperoxidase antibodies and adverse reactions to clozapine
The 17 references without a DOI — listed, not checked
no DOI — not checkedUber chronische vergigtung mit steinkohlentheerbenzin vir todesfalle
no DOI — not checkedSur un cas de purpura attribue a l'intoxication par le benzene
no DOI — not checkedLeucemie aique au cours de intoxication benzenique. Sur origine toxique de certaines leucemies aigues et leurs relations avec le anemies graves
no DOI — not checkedBenzene Carcinogenicity
no DOI — not checkedHematotoxicity in humans
no DOI — not checkedBenzene Carcinogenicity
no DOI — not checkedBenzene Carcinogenicity
no DOI — not checkedBenzene metabolism by ethanol‐, acetone‐, and benzene‐inducible cytochrome P450IIE1 in rat and rabbit liver microsomes
no DOI — not checkedIn vitro metabolism of benzo(a)pyrene by human liver microsomes and lymphocytes
no DOI — not checkedIncorporation of heterogeneous enzyme distribution into a physiological model for benzene, phenol and hydroquinone
no DOI — not checkedHematopoietic effects of benzene inhalation assessed by murine long‐term bone marrow culture
no DOI — not checkedCell‐specific metabolism in benzene toxicity. A metabolic basis for benzene induced toxicity at the level of the progenitor cell in human bone marrow
no DOI — not checkedFlow cytometric characterization of stimulation, free radical formation, peroxidase activity and phagocytosis of human granulocytes with 2,7‐dichlorofluorescein
no DOI — not checkedProgrammed cell death (apoptosis) in hematopoiesis
no DOI — not checkedInduction of apoptosis by benzene metabolites in HL60 and CD34+ human bone marrow progenitor cells
no DOI — not checkedNAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT‐diaphorase activity and mitomycin sensitivity
no DOI — not checkedCloning and purification of a mutant DT‐diaphorase protein from human colon and lung cancer cell lines
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