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Rituximab, an Anti-CD20 Monoclonal Antibody: History and Mechanism of Action

https://doi.org/10.1111/j.1600-6143.2006.01288.x
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68/68 checkable references clean · checked 2026-07-23

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

23 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 68 checked references that resolve
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New Crossmatch Technique Eliminates Interference by Humanized and Chimeric Monoclonal Antibodies
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The relationship of FcγRIIIa genotype to degree of B cell depletion by rituximab in the treatment of systemic lupus erythematosus
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Two Immunoglobulin G Fragment C Receptor Polymorphisms Independently Predict Response to Rituximab in Patients With Follicular Lymphoma
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Long-term effects of anti-CD20 monoclonal antibody treatment of cryoglobulinaemic glomerulonephritis
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No clinical evidence for CD4+ cell depletion caused by rituximab
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Rituximab treatment results in impaired secondary humoral immune responsiveness
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Hapten-Induced Primary and Memory Humoral Responses Are Inhibited by the Infusion of Anti-CD20 Monoclonal Antibody (IDEC-C2B8, Rituximab)
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Rituximab Inhibits the In Vivo Primary and Secondary Antibody Response to a Neoantigen, Bacteriophage phiX174
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Posttransplant Lymphoma A Single-Center Experience of 500 Liver Transplantations
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REVERSAL OF STEROID- AND ANTI-LYMPHOCYTE ANTIBODY- RESISTANT REJECTION USING INTRAVENOUS IMMUNOGLOBULIN (IVIG) IN RENAL TRANSPLANT RECIPIENTS
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Maintenance of Serological Memory by Polyclonal Activation of Human Memory B Cells
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Role of B cells as antigen-presenting cells in vivo revisited: antigen-specific B cells are essential for T cell expansion in lymph nodes and for systemic T cell responses to low antigen concentrations
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Molecular Heterogeneity in Acute Renal Allograft Rejection Identified by DNA Microarray Profiling
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Association of CD20+ Infiltrates with Poorer Clinical Outcomes in Acute Cellular Rejection of Renal Allografts
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Refractory acute kidney transplant rejection with CD20 graft infiltrates and successful therapy with rituximab
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Depletion of B Cells by a Humanized Anti-CD20 Antibody PRO70769 in Macaca Fascicularis
resolves10.1016/j.coi.2005.04.005
The role of APRIL and BAFF in lymphocyte activation
resolves10.1517/14712598.5.1.S61
Molecules involved in T–B co-stimulation and B cell homeostasis: possible targets for an immunological intervention in autoimmunity
resolves10.1093/annonc/11.suppl_1.S113
Humanized anti-CD20 monoclonal antibody (Rituximab) in post transplant B-lymphoproliferative disorder: A retrospective analysis on 32 patients
resolves10.1080/08880010390203125
Anti-CD20 Monoclonal Antibody (Rituximab) for Therapy of Mediastinal CD20-Positive Large B-Cell Non-Hodgkin Lymphoma with a Local Tumor Extension into the Lung of a 10-Year-Old Girl
resolves10.1034/j.1399-3046.2003.00024.x
Treatment of monomorphic B‐cell lymphoma with rituximab after liver transplantation in a child
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Successful treatment with rituximab of lymphoproliferative disorder in a child after cardiac transplantation
resolves10.1097/00007890-200210150-00018
Successful treatment of posttransplant lymphoproliferative disease with prolonged rituximab treatment in intestinal transplant recipients
resolves10.1016/S1053-2498(00)00326-0
Treatment of post-transplant lymphoproliferative disorder with monoclonal cd20 antibody (rituximab) after heart transplantation
resolves10.1046/j.1397-3142.2003.00135.x
The use of rituximab, anti‐CD20 monoclonal antibody, in pediatric transplantation
resolves10.1111/j.1600-6143.2005.01098.x
Effect of Anti‐CD 20 Antibody Rituximab in Patients with Post‐Transplant Lymphoproliferative Disorder (PTLD)
resolves10.1016/j.transproceed.2004.12.114
New Strategy for ABO-Incompatible Living Donor Liver Transplantation With Anti-CD20 Antibody (Rituximab) and Plasma Exchange
resolves10.1111/j.1600-6143.2004.00507.x
Plasmapheresis, CMV Hyperimmune Globulin, and Anti-CD20 Allow ABO-Incompatible Renal Transplantation Without Splenectomy
resolves10.1111/j.1399-0012.2004.00151.x
Preconditioning regimen consisting of anti‐CD20 monoclonal antibody infusions, splenectomy and DFPP‐enabled non‐responders to undergo ABO‐incompatible kidney transplantation
resolves10.1111/j.1600-6143.2004.00653.x
ABO Incompatible Kidney Transplantations Without Splenectomy, Using Antigen-Specific Immunoadsorption and Rituximab
resolves10.1097/01.TP.0000149337.40911.E4
Successful Use of Anti-CD20 Monoclonal Antibody (Rituximab) for ABO-Incompatible Living-Related Liver Transplantation
resolves10.1111/j.1600-6143.2005.01031.x
ABO Incompatible High‐Titer Renal Transplantation without Splenectomy or Anti‐CD20 Treatment
resolves10.1016/S0003-4975(02)03824-9
Treatment of humoral rejection with rituximab
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Anti-CD20 monoclonal antibody (rituximab) therapy for acute cardiac humoral rejection: a case report
resolves10.1111/j.1600-6143.2004.00454.x
Rituximab as Treatment for Refractory Kidney Transplant Rejection
resolves10.1007/s00467-005-2013-7
Rituximab treatment for posttransplant lymphoproliferative disorder (PTLD) induces complete remission of recurrent nephrotic syndrome
The 23 references without a DOI — listed, not checked
no DOI — not checkedInterferon-g induces CD20 expression on multiple myeloma cells via induction of Pu.1 and augments rituximab binding to myeloma cells.
no DOI — not checkedPrimary analysis of a double-blind, placebo-controlled, dose-ranging trial of rituximab, an anti-CD20 monoclonal antibody, in patients with rheumatoid arthritis receiving methotrexate (DANCER TRIAL).
no DOI — not checkedThe anti-tumor effect of monoclonal anti-CD20 antibody (mAb) therapy includes direct anti-proliferative activity and induction of apoptosis in CD20 positive non-Hodgkin’s lymphoma (NHL) cell lines.
no DOI — not checkedEffective B-cell depletion in peripheral blood and tissue by single-dose rituximab in kidney transplant recipients: A pilot study.
no DOI — not checkedImmunomodulatory impact of rituximab and thymoglobuin therapy in liver transplantation.
no DOI — not checkedPost-transplant lymphoproliferative disorders (PTLD) in kidney transplantation: Report of 220 cases of a French registry.
no DOI — not checkedMeasurement of HLA antibody specificity by single antigen beads and MESF quatitation demonstrates efficacy of rituximab desensitization.
no DOI — not checkedCD40-stimulated B lymphocytes pulsed with tumor antigens are effective antigen-presenting cells that can generate specific T cells.
no DOI — not checkedAnti-CD20 monoclonal antibody (rituximab) treatment for Epstein-Barr virus-associated, B-cell lymphoproliferative disease in pediatric liver transplant recipients.
no DOI — not checkedAnti-CD20 monoclonal antibody (rituximab) for pediatric post-transplant lymphoproliferative disorders: A preliminary multicenter experience.
no DOI — not checkedCD20 ligation using rituximab (anti-CD20 monoclonal antibody) inhibits growth of EBV infected B cells from a patient with PTLD.
no DOI — not checkedAnti-CD20 monoclonal antibody (rituximab) for post-transplant lymphoproliferative disease treatment (PTLD).
no DOI — not checkedAnti-CD20 antibody rituximab administration in patients with late-occurring lymphomas after solid organ transplant.
no DOI — not checkedRituximab is effective therapy for post-transplant lymphoproliferative disorder (PTLD) not responding to reduction in immunosuppression: A prospective trial in adults and children.
no DOI — not checkedLymphocyte subsets may discern treatment effects in children with post-transplant lymphoproliferative disorder (PTLD).
no DOI — not checkedThymoglobulin (T) in the management of steroid resistant acute cellular rejection (SRACR) in children.
no DOI — not checkedChoquet S Leblond V Herbrecht R et al. Efficacy and safety of rituximab in B-cell post-transplant lymphoproliferative disorders: Results of a prospective multicentre phase II study. Blood 2005.
no DOI — not checkedSuccessful ABO-incompatible kidney transplantation for non-responders with the use of anti-CD20 monoclonal antibody and plasmapheresis.
no DOI — not checkedSuccessful kidney transplant in ABO incompatible patients after plasmapheresis and thymoglobulin under a steroid avoidance protocol.
no DOI — not checkedLiving donor kidney transplantation in positive crossmatch patients.
no DOI — not checkedEarly allograft outcomes in patients with antibody mediated rejection treated with rituximab.
no DOI — not checkedRituximab rescue for refractory antibody mediated rejection after kidney transplantation.
no DOI — not checkedAchieving desensitization and preventing humoral rejection in positive crossmatch living donor kidney transplantation.
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