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Nod1 Detects a Unique Muropeptide from Gram-Negative Bacterial Peptidoglycan

https://doi.org/10.1126/science.1084677
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28/28 checkable references clean · checked 2026-07-22

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

5 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 28 checked references that resolve
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Toll-like receptors: critical proteins linking innate and acquired immunity
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Toll-like receptors and innate immunity
resolves10.1074/jbc.274.21.14560
Nod1, an Apaf-1-like Activator of Caspase-9 and Nuclear Factor-κB
resolves10.1074/jbc.274.19.12955
Human CARD4 Protein Is a Novel CED-4/Apaf-1 Cell Death Family Member That Activates NF-κB
resolves10.1074/jbc.M009728200
Human Nod1 Confers Responsiveness to Bacterial Lipopolysaccharides
resolves10.1093/embo-reports/kve155
CARD4/Nod1 mediates NF‐κB and JNK activation by invasive Shigella flexneri
resolves10.1074/jbc.M008072200
Nod2, a Nod1/Apaf-1 Family Member That Is Restricted to Monocytes and Activates NF-κB
resolves10.1038/35079114
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
resolves10.1038/35079107
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
resolves10.4049/jimmunol.168.8.4012
Two Lipoproteins Extracted from <i>Escherichia coli</i> K-12 LCD25 Lipopolysaccharide Are the Major Components Responsible for Toll-Like Receptor 2-Mediated Signaling
resolves10.1016/S0021-9258(19)49903-1
Peptidoglycan composition of a highly methicillin-resistant Staphylococcus aureus strain. The role of penicillin binding protein 2A.
resolves10.1016/0003-2697(88)90468-X
Separation and quantification of muropeptides with high-performance liquid chromatography
resolves10.1007/s002390010136
Identification of Four Families of Peptidoglycan Lytic Transglycosylases
resolves10.1074/jbc.C200651200
Nod2 Is a General Sensor of Peptidoglycan through Muramyl Dipeptide (MDP) Detection
resolves10.1074/jbc.C200673200
Host Recognition of Bacterial Muramyl Dipeptide Mediated through NOD2
resolves10.1074/jbc.275.19.14084
Analysis by High Density cDNA Arrays of Altered Gene Expression in Human Intestinal Epithelial Cells in Response to Infection with the Invasive Enteric BacteriaSalmonella
resolves10.1038/35074106
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
resolves10.1099/00221287-144-5-1359
Molecular characterization of an autolytic amidase of Listeria monocytogenes EGD
resolves10.1016/S1074-7613(00)80086-2
Unresponsiveness of MyD88-Deficient Mice to Endotoxin
resolves10.1074/jbc.M003415200
An Induced Proximity Model for NF-κB Activation in the Nod1/RICK and RIP Signaling Pathways
resolves10.1038/416190a
Involvement of receptor-interacting protein 2 in innate and adaptive immune responses
resolves10.1038/416194a
RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems
resolves10.1016/S0092-8674(00)80172-5
The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults
resolves10.1038/414756a
Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein
resolves10.1126/science.1070216
Requirement for a Peptidoglycan Recognition Protein (PGRP) in Relish Activation and Antibacterial Immune Responses in <i>Drosophila</i>
resolves10.1038/nature734
The Drosophila immune response against Gram-negative bacteria is mediated by a peptidoglycan recognition protein
resolves10.1038/nature735
Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli
resolves10.1038/ni922
The Drosophila immune system detects bacteria through specific peptidoglycan recognition
The 5 references without a DOI — listed, not checked
no DOI — not checkedS. E. Girardin et al . data not shown.
no DOI — not checkedJ.-H. Höltje, Microbiol. Mol. Biol. Rev.62, 181 (1988).
no DOI — not checkedSee supporting data on Science Online.
no DOI — not checkedT. Pedron et al . in preparation.
no DOI — not checkedWe thank M. Mavris for critical reading of the manuscript; the PTR/TLR group at the Institut Pasteur for helpful discussions; those individuals who donated bacterial strains plasmids and bacterial products; R. Athman for advice on primary cell cultures; M. Parmier for plasmid preparations; and the PT3 technical platform at the Institut Pasteur for mass spectrometry analyses. Supported by a Programme Transversal de Recherche grant from the Institut Pasteur (S.E.G. D.J.P.); a grant from Danone Vitapole Paris (S.E.G.); a postdoctoral fellowship from the Fundação para a Ciência e a Tecnologia Portugal (I.G.B.); and a studentship from CAPES/MEC Brazil (L.A.M.C.). P.J.S. is a Howard Hughes International Research Scholar.
What this badge says. CiteStamped means the CHECKABLE references of this work were clean at the dated check: each resolved to a known work in a public registry, and none carried a retraction notice at that time. It says nothing about the quality, findings, or importance of the work itself, and nothing about references deposited without a DOI.

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