Reference health
Cellular and Molecular Mechanisms of Drug Dependence
147/147 checkable references clean · checked 2026-07-23
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
81 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 147 checked references that resolve
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Pertussis toxin blocks the outward currents evoked by opiate and α2-agonists in locus coeruleus neurons
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Tolerance of locus coeruleus neurones to morphine and suppression of withdrawal response by clonidine
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Low doses of methylnaloxonium in the nucleus accumbens antagonize hyperactivity induced by heroin in the rat
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Morphine tolerance and dependence in the locus coeruleus: Single cell studies in brain slices
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Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle
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Nonrepinephrine-containing locus coeruleus neurons in behaving rats exhibit pronounced responses to non-noxious environmental stimuli
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Low doses of ethanol disrupt sensory responses of brain noradrenergic neurones
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The Brain Nucleus Locus Coeruleus: Restricted Afferent Control of a Broad Efferent Network
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Enkephalin levels decrease in rat striatum during morphine abstinence
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Neurotransmitters: past, present, and future directions
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Toxicity Associated With Long-term Intravenous Heroin and Cocaine Self-administration in the Rat
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Anatomically Distinct Opiate Receptor Fields Mediate Reward and Physical Dependence
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Ventral tegmental site of opiate reward: Antagonism by a hydrophilic opiate receptor blocker
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Morphine withdrawal syndrome: Differential participation of structures located within the amygdaloid complex and striatum of the rat
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Acquisition of behavioral tolerance to ethanol as a function of reinforced practice in rats
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Enkephalin: Radioimmunoassay and radioreceptor assay in morphine dependent rats
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Mechanisms of Tolerance to and Dependence on Narcotic Analgesic Drugs
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Alcohol, Amines, and Alkaloids: A Possible Biochemical Basis for Alcohol Addiction
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Initial Sensitivity of Rat Inbred Strains to Acute Alcohol
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6-Hydroxydopamine lesion of the dopamine mesocorticolimbic cell bodies increases (+)-amphetamine self-administration
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Increased sensitivity to amphetamine and facilitation of amphetamine self-administration after 6-hydroxydopamine lesions of the amygdala
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The importance of postingestional factors in limiting alcohol consumption in the rat
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Chronic ethanol exposure potentiates the locomotor-activating effects of corticotropin-releasing factor (CRF) in rats
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Electrophysiological effects of cocaine in the mesoaccumbens dopamine system: studies in the ventral tegmental area
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Nucleus locus ceruleus: new evidence of anatomical and physiological specificity
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An iontophoretic survey of opioid peptide actions in the rat limbic system: in search of opiate epileptogenic mechanisms
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Specific versus non-specific actions of opioids on hippocampal neurones in the rat brain
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A DEMONSTRATION OF NALOXONE‐PRECIPITATED OPIATE WITHDRAWAL ON SINGLE NEURONES IN THE MORPHINE‐TOLERANT/DEPENDENT RAT BRAIN
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Chronic ethanol tolerance through free-choice drinking in the P line of alcohol-preferring rats
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Abstinence Symptomatology and Psychiatric Diagnosis in Cocaine Abusers
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Low doses of ethanol activate dopaminergic neurons in the ventral tegmental area
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Self-administration of methionine enkephalin into the nucleus accumbens
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The role of mesolimbic dopamine in conditioned locomotion produced by amphetamine.
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CONDITIONED NALORPHINE‐INDUCED ABSTINENCE CHANGES: PERSISTENCE IN POST MORPHINE‐DEPENDENT MONKEYS<sup>1</sup>
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Aversive properties of opiate receptor blockade: evidence for exclusively central mediation in naive and morphine-dependent rats
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Morphine abstinence syndrome in rabbits precipitated by injection of morphine antagonists into the ventricular system and restricted parts of it
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Identification of two related pentapeptides from the brain with potent opiate agonist activity
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An Experimental Study of the Etiology of “Rum Fits” and Delirium Tremens
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Post-amphetamine depression of self-stimulation responding from the substantia nigra: Reversal by tricyclic antidepressants
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Picrotoxinin receptor ligand blocks anti-punishment effects of alcohol
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The D1 dopamine receptor antagonist SCH 23390 increases cocaine self-administration in the rat
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Destruction of the locus coeruleus or the dorsal NE bundle does not alter the release of punished responding by ethanol and chlordiazepoxide
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Reward and detection thresholds for brain stimulation: dissociative effects of cocaine
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Amphetamine and the reward system: Evidence for tolerance and post-drug depression
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Effects of chronic amphetamine or reserpine on self-stimulation responding: Animal model of depression?
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Reversal of the anti-conflict action of valproate by various GABA and benzodiazepine antagonists
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Destruction of dopaminergic nerve terminals in nucleus accumbens: Effect on d-amphetamine self-administration
resolves10.1126/science.2867600
Systemic Ethanol: Selective Enhancement of Responses to Acetylcholine and Somatostatin in Hippocampus
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Double immunostaining reveals distinctions among opioid peptidergic neurons in the medial basal hypothalamus
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Ethanol stimulates the firing rate of nigral dopaminergic neurons in unanesthetized rats
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Low doses of ethanol inhibit the firing of neurons in the substantia nigra, pars reticulata: a GABAergic effect?
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In vivo studies of the regulation of neuropeptide stores in structures of the rat brain
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Chronic ethanol causes heterologous desensitization of receptors by reducing αsmessenger RNA
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Contents of monoamines in forebrain regions of alcohol-preferring (P) and -nonpreferring (NP) lines of rats
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Alcohol Preference in the Rat: Reduction Following Depletion of Brain Serotonin
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Efferent connections and nigral afferents of the nucleus accumbens septi in the rat
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Ethanol Specifically Potentiates GABA-Mediated Neurotransmission in Feline Cerebral Cortex
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On the potassium conductance increased by opioids in rat locus coeruleus neurones.
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Dopamine receptors mediate alterations in striato-nigral dynorphin and substance p pathways
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Self-administration of D-Ala2-Met-enkephalinamide at hypothalamic self-stimulation sites
resolves10.1038/331585a0
Positron emission tomographic studies of the cortical anatomy of single-word processing
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Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats
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Afferent projections to the ventral tegmental area of Tsai and interfascicular nucleus: A horseradish peroxidase study in the rat
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Drug-environment interaction: Context dependency of cocaine-induced behavioral sensitization
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Selective breeding of rats for differences in reactivity to alcohol. An approach to an animal model of alcoholism. I. General procedures.
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Cocaine Receptors on Dopamine Transporters Are Related to Self-Administration of Cocaine
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Disruption of cocaine self-administration following 6-hydroxydopamine lesions of the ventral tegmental area in rats
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On the role of ascending catecholaminergic systems in intravenous self-administration of cocaine
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Extinction and recovery of cocaine self-administration following 6-hydroxydopamine lesions of the nucleus accumbens
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Physiological correlates of ethanol intoxication, tolerance, and dependence in rat cerebellar purkinje cells
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Ethanol increases single unit activity in the inferior olivary nucleus
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Initiation of Ethanol Reinforcement using a Sucrose‐Substitution Procedure in Food‐ and Water‐Sated Rats
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Oral ethanol reinforcement in the rat: Effect of the partial inverse benzodiazepine agonist RO15-4513
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Opiate agonist-antagonist interaction at cortical neurones of naive and tolerant/dependent rats
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Actions of opiates upon single unit activity in the cortex of naive and tolerant rats
resolves10.15288/jsa.1980.41.242
Self-rating of alcohol intoxication by young men with and without family histories of alcoholism.
resolves10.1146/annurev.pa.09.040169.002411
Self Administration of and Behavioral Dependence on Drugs
resolves10.1126/science.935870
Morphine Analgesic Tolerance: Its Situation Specificity Supports a Pavlovian Conditioning Model
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<i>Response</i>
: Morphine Tolerance: Is There Evidence for a Conditioning Model?
resolves10.1016/0006-8993(87)91323-0
Effects of ethanol on CA1 and CA3 pyramidal cells in the hippocampal slice preparation: an intracellular study
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The effects of ethanol on cerebellar purkinje cell discharge pattern and inhibition evoked by local surface stimulation
resolves10.1139/y80-072
The effects of ethanol on cerebellar Purkinje cells in naive and alcohol-dependent rats
resolves10.1016/0091-3057(78)90292-7
Clonidine antagonizes naloxone-induced suppression of conditioned behavior and body weight loss in morphine-dependent rats
resolves10.1016/0024-3205(84)90440-5
The neural substrates of apomorphine-stimulated locomotor activity following denervation of the nucleus accumbens
resolves10.1111/j.1530-0277.1988.tb00157.x
Tolerance and the Etiology of Alcoholism: Hypothesis and Mechanism
resolves10.1111/j.1749-6632.1987.tb48666.x
Membrane Structural Alterations Caused by Chronic Ethanol Consumption: The Molecular Basis of Membrane Tolerancea
resolves10.1111/j.1471-4159.1980.tb06612.x
Alterations in γ‐Aminobutyric Acid Receptor Sensitivity Following Acute and Chronic Ethanol Treatments
resolves10.1016/0091-3057(83)90140-5
The interactions of ethanol with the benzodiazepine-GABA receptor-ionophore complex
resolves10.1016/0361-9230(87)90071-2
Effects of opiate antagonist treatment into either the periaqueductal grey or nucleus accumbens on heroin-induced locomotor activation
resolves10.1007/BF00431681
Blockade of nucleus accumbens opiate receptors attenuates intravenous heroin reward in the rat
resolves10.1016/0306-4522(80)90071-8
Biochemical evidence for γ-aminobutyrate containing fibres from the nucleus accumbens to the substantia nigra and ventral tegmental area in the rat
resolves10.1016/0014-2999(87)90130-0
Opposite effects of μ and κ opiates on the firing-rate of dopamine cells in the substantia nigra of the rat
resolves10.1523/JNEUROSCI.06-01-00274.1986
Electrophysiological evidence for the existence of both D-1 and D-2 dopamine receptors in the rat nucleus accumbens
resolves10.1037/0021-843X.97.2.118
The neurobiology of craving: Implications for the understanding and treatment of addiction.
resolves10.1016/0091-3057(86)90553-8
Effects of a D1 and a D2 dopamine antagonist on the self-administration of cocaine and piribedil by Rhesus monkeys
resolves10.1016/0006-8993(80)90100-6
Inquiry into endorphinergic feedback mechanisms during the development of opiate tolerance/dependence
resolves10.1007/BF00496868
Attenuation of intravenous amphetamine reinforcement by central dopamine blockade in rats
resolves10.1126/science.1114313
Increased Lever Pressing for Amphetamine After Pimozide in Rats: Implications for a Dopamine Theory of Reward
resolves10.1016/0006-8993(79)90442-6
A new method for receptor autoradiography: [3H]Opioid receptors in rat brain
resolves10.1016/0028-3908(87)90169-9
Clonidine and the hyper-responsiveness of dorsal horn neurones following morphine withdrawal in the spinal cat
resolves10.1016/0006-8993(76)90832-5
Enkephalin-induced inhibition of cortical neurones and the lack of this effect in morphine tolerant/dependent rats
resolves10.1126/science.451610
Opioid Peptides May Excite Hippocampal Pyramidal Neurons by Inhibiting Adjacent Inhibitory Interneurons
resolves10.1016/0091-3057(85)90110-8
Disruption of cocaine and heroin self-administration following kainic acid lesions of the nucleus accumbens
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no DOI — not checkedWOODS, J.H., RECENT ADV STUDIES A: 413 (1970).
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