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A Novel Immunogen Selectively Eliciting CD8 <sup>+</sup> T Cells but Not CD4 <sup>+</sup> T Cells Targeting Immunodeficiency Virus Antigens
39/39 checkable references clean · checked 2026-07-23
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
3 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 39 checked references that resolve
resolves10.1073/pnas.1620788114
Effectiveness of UNAIDS targets and HIV vaccination across 127 countries
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Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome
resolves10.1128/JVI.72.1.164-169.1998
Administration of an Anti-CD8 Monoclonal Antibody Interferes with the Clearance of Chimeric Simian/Human Immunodeficiency Virus during Primary Infections of Rhesus Macaques
resolves10.1126/science.283.5403.857
Control of Viremia in Simian Immunodeficiency Virus Infection by CD8
<sup>+</sup>
Lymphocytes
resolves10.1084/jem.20040432
Cytotoxic T Lymphocyte–based Control of Simian Immunodeficiency Virus Replication in a Preclinical AIDS Vaccine Trial
resolves10.1128/JVI.00171-06
Vaccine-Induced Cellular Immune Responses Reduce Plasma Viral Concentrations after Repeated Low-Dose Challenge with Pathogenic Simian Immunodeficiency Virus SIVmac239
resolves10.1038/nature10003
Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine
resolves10.1038/nature10766
Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys
resolves10.1371/journal.ppat.1007143
A recombinant herpesviral vector containing a near-full-length SIVmac239 genome produces SIV particles and elicits immune responses to all nine SIV gene products
resolves10.1126/science.1058915
Control of a Mucosal Challenge and Prevention of AIDS by a Multiprotein DNA/MVA Vaccine
resolves10.1128/JVI.75.23.11891-11896.2001
Rapid Appearance of Secondary Immune Responses and Protection from Acute CD4 Depletion after a Highly Pathogenic Immunodeficiency Virus Challenge in Macaques Vaccinated with a DNA Prime/Sendai Virus Vector Boost Regimen
resolves10.1093/infdis/jiw500
First-in-Human Evaluation of the Safety and Immunogenicity of an Intranasally Administered Replication-Competent Sendai Virus–Vectored HIV Type 1 Gag Vaccine: Induction of Potent T-Cell or Antibody Responses in Prime-Boost Regimens
resolves10.1038/nm1520
CD8+ T-cell responses to different HIV proteins have discordant associations with viral load
resolves10.1038/nri2357
Impact of MHC class I diversity on immune control of immunodeficiency virus replication
resolves10.1128/JVI.02634-13
Control of Simian Immunodeficiency Virus Replication by Vaccine-Induced Gag- and Vif-Specific CD8
<sup>+</sup>
T Cells
resolves10.1128/JVI.00601-14
Vaccination with
<i>gag</i>
,
<i>vif</i>
, and
<i>nef</i>
Gene Fragments Affords Partial Control of Viral Replication after Mucosal Challenge with SIVmac239
resolves10.1371/journal.ppat.1006529
Vaccine-induced immune responses against both Gag and Env improve control of simian immunodeficiency virus replication in rectally challenged rhesus macaques
resolves10.1186/s12967-015-0392-5
A human immune data-informed vaccine concept elicits strong and broad T-cell specificities associated with HIV-1 control in mice and macaques
resolves10.1038/mt.2016.3
Novel Conserved-region T-cell Mosaic Vaccine With High Global HIV-1 Coverage Is Recognized by Protective Responses in Untreated Infection
resolves10.1186/s12977-018-0429-y
CD8+ T cells specific for conserved, cross-reactive Gag epitopes with strong ability to suppress HIV-1 replication
resolves10.1128/JVI.68.12.8056-8063.1994
CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection
resolves10.1038/nature01441
CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes
resolves10.1126/science.1082305
Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory
resolves10.1126/science.1083317
Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help
resolves10.1128/JVI.02032-14
Vaccine-Induced CD107a<sup>+</sup>CD4<sup>+</sup>T Cells Are Resistant to Depletion following AIDS Virus Infection
resolves10.1128/JVI.01120-09
Impact of Cytotoxic-T-Lymphocyte Memory Induction without Virus-Specific CD4
<sup>+</sup>
T-Cell Help on Control of a Simian Immunodeficiency Virus Challenge in Rhesus Macaques
resolves10.1128/JVI.06226-11
Impact of Vaccination on Cytotoxic T Lymphocyte Immunodominance and Cooperation against Simian Immunodeficiency Virus Replication in Rhesus Macaques
resolves10.1371/journal.ppat.1005247
Broadening of Virus-Specific CD8+ T-Cell Responses Is Indicative of Residual Viral Replication in Aviremic SIV Controllers
resolves10.1128/JVI.07077-11
Association of Major Histocompatibility Complex Class I Haplotypes with Disease Progression after Simian Immunodeficiency Virus Challenge in Burmese Rhesus Macaques
resolves10.1371/journal.pone.0054300
A Novel Protective MHC-I Haplotype Not Associated with Dominant Gag-Specific CD8+ T-Cell Responses in SIVmac239 Infection of Burmese Rhesus Macaques
resolves10.1126/scitranslmed.aav1800
Strong T
<sub>H</sub>
1-biased CD4 T cell responses are associated with diminished SIV vaccine efficacy
resolves10.1128/jvi.74.14.6564-6569.2000
A Cytoplasmic RNA Vector Derived from Nontransmissible Sendai Virus with Efficient Gene Transfer and Expression
resolves10.1038/srep30153
Association of lymph-node antigens with lower Gag-specific central-memory and higher Env-specific effector-memory CD8+ T-cell frequencies in a macaque AIDS model
resolves10.1128/JVI.00557-16
Biphasic CD8
<sup>+</sup>
T-Cell Defense in Simian Immunodeficiency Virus Control by Acute-Phase Passive Neutralizing Antibody Immunization
The 3 references without a DOI — listed, not checked
no DOI — not checkedUNAIDS. 2019. Global HIV & AIDS statistics—2019 fact sheet. https://www.unaids.org/en/resources/fact-sheet.
no DOI — not checkedScience Council of Japan. 2006. Guidelines for proper conduct of animal experiments. http://www.scj.go.jp/ja/info/kohyo/pdf/kohyo-20-k16-2e.pdf.
no DOI — not checkedWeatherall D (ed). 2006. The use of non-human primates in research. https://royalsociety.org/topics-policy/publications/2006/weatherall-report/.
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work were clean at the dated check: each resolved to a known work in a public registry, and none
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