Reference health

Claudins and the Kidney

https://doi.org/10.1146/annurev-physiol-030212-183705
CiteStamped reference-health badge
115/115 checkable references clean · checked 2026-07-23

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

5 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 115 checked references that resolve
resolves10.1083/jcb.143.2.391
A Single Gene Product, Claudin-1 or -2, Reconstitutes Tight Junction Strands and Recruits Occludin in Fibroblasts
resolves10.1126/science.285.5424.103
Paracellin-1, a Renal Tight Junction Protein Required for Paracellular Mg <sup>2+</sup> Resorption
resolves10.1186/gb-2009-10-8-235
The claudins
resolves10.1016/j.febslet.2011.01.028
Predicted expansion of the claudin multigene family
resolves10.1038/35067088
Multifunctional strands in tight junctions
resolves10.1146/annurev.physiol.68.040104.131404
CLAUDINS AND EPITHELIAL PARACELLULAR TRANSPORT
resolves10.1016/j.bbamem.2007.10.018
Structure and function of claudins
resolves10.1111/j.1432-1033.2004.04186.x
A novel four transmembrane spanning protein, CLP24
resolves10.1152/ajpcell.00547.2002
Claudin extracellular domains determine paracellular charge selectivity and resistance but not tight junction fibril architecture
resolves10.1242/jcs.02631
Paracellin-1 and the modulation of ion selectivity of tight junctions
resolves10.1016/j.bbrc.2007.03.078
The first extracellular domain of claudin-7 affects paracellular Cl− permeability
resolves10.1128/JVI.02262-08
Residues in a Highly Conserved Claudin-1 Motif Are Required for Hepatitis C Virus Entry and Mediate the Formation of Cell-Cell Contacts
resolves10.1096/fj.07-8319com
Formation of tight junction: determinants of homophilic interaction between classic claudins
resolves10.1016/S0014-5793(00)01744-0
<i>Clostridium perfringens</i> enterotoxin binds to the second extracellular loop of claudin‐3, a tight junction integral membrane protein
resolves10.1074/jbc.M109005200
Multi-PDZ Domain Protein 1 (MUPP1) Is Concentrated at Tight Junctions through Its Possible Interaction with Claudin-1 and Junctional Adhesion Molecule
resolves10.1083/jcb.147.6.1351
Direct Binding of Three Tight Junction-Associated Maguks, Zo-1, Zo-2, and Zo-3, with the Cooh Termini of Claudins
resolves10.1007/s00418-001-0359-x
Formation of tight junction strands by expression of claudin-1 mutants in their ZO-1 binding site in MDCK cells
resolves10.1152/physiol.00027.2004
The Molecular Physiology of Tight Junction Pores
resolves10.1078/0171-9335-00366
The C-terminal cytoplasmic tail of claudins 1 and 5 but not its PDZ-binding motif is required for apical localization at epithelial and endothelial tight junctions
resolves10.1007/s00232-004-0673-z
The Cytoplasmic Tails of Claudins Can Influence Tight Junction Barrier Properties through Effects on Protein Stability
resolves10.1074/jbc.M602902200
Convergent and Divergent Ligand Specificity among PDZ Domains of the LAP and Zonula Occludens (ZO) Families
resolves10.1242/jcs.01735
Palmitoylation of claudins is required for efficient tight-junction localization
resolves10.1073/pnas.0306924101
Disease-causing mutant WNK4 increases paracellular chloride permeability and phosphorylates claudins
resolves10.1242/jcs.02901
Phosphorylation of paracellin-1 at Ser217 by protein kinase A is essential for localization in tight junctions
resolves10.1110/ps.0233903
Expression, solubilization, and biochemical characterization of the tight junction transmembrane protein claudin‐4
resolves10.1074/jbc.M110.195578
Claudin-2 Forms Homodimers and Is a Component of a High Molecular Weight Protein Complex
resolves10.1083/jcb.147.4.891
Manner of Interaction of Heterogeneous Claudin Species within and between Tight Junction Strands
resolves10.1007/s00018-005-5472-x
On the self-association potential of transmembrane tight junction proteins
resolves10.1074/jbc.M703547200
Regulation of Heterotypic Claudin Compatibility
resolves10.1073/pnas.0907724106
Claudin-16 and claudin-19 interaction is required for their assembly into tight junctions and for renal reabsorption of magnesium
resolves10.1152/ajplung.00182.2003
Role of claudin interactions in airway tight junctional permeability
resolves10.1016/S0171-9335(99)80086-7
Claudin-1 contributes to the epithelial barrier function in MDCK cells
resolves10.1172/JCI12464
Regulated expression of claudin-4 decreases paracellular conductance through a selective decrease in sodium permeability
resolves10.1242/jcs.113.19.3387
Inducible expression of claudin-1-myc but not occludin-VSV-G results in aberrant tight junction strand formation in MDCK cells
resolves10.1128/MCB.24.19.8408-8417.2004
Selective Decrease in Paracellular Conductance of Tight Junctions: Role of the First Extracellular Domain of Claudin-5
resolves10.1074/jbc.M213286200
Claudin-8 Expression in Madin-Darby Canine Kidney Cells Augments the Paracellular Barrier to Cation Permeation
resolves10.1152/ajpregu.90596.2008
Effect of claudins 6 and 9 on paracellular permeability in MDCK II cells
resolves10.1152/ajprenal.00116.2003
Reversal of charge selectivity in cation or anion-selective epithelial lines by expression of different claudins
resolves10.1152/ajprenal.00087.2007
Renal localization and function of the tight junction protein, claudin-19
resolves10.1083/jcb.153.2.263
Conversion of <i>Zonulae Occludentes</i> from Tight to Leaky Strand Type by Introducing Claudin-2 into Madin-Darby Canine Kidney I Cells
resolves10.1242/jcs.040113
Claudin-10 exists in six alternatively spliced isoforms that exhibit distinct localization and function
resolves10.1152/ajprenal.0021.2001
Claudin-2 is selectively expressed in proximal nephron in mouse kidney
resolves10.1152/ajprenal.00384.2003
Expression of claudin-7 and -8 along the mouse nephron
resolves10.1242/jcs.00165
Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells
resolves10.1085/jgp.200810154
Molecular Basis for Cation Selectivity in Claudin-2–based Paracellular Pores: Identification of an Electrostatic Interaction Site
resolves10.1152/ajpcell.00038.2002
Claudins create charge-selective channels in the paracellular pathway between epithelial cells
resolves10.1111/j.1749-6632.2009.04038.x
Cysteine Mutagenesis to Study the Structure of Claudin‐2 Paracellular Pores
resolves10.1007/BF01870095
Dimensions of polar pathways through rabbit gallbladder epithelium
resolves10.1152/ajpcell.2001.281.2.C388
Functional modeling of tight junctions in intestinal cell monolayers using polyethylene glycol oligomers
resolves10.1242/jcs.021485
The density of small tight junction pores varies among cell types and is increased by expression of claudin-2
resolves10.1152/ajprenal.00214.2009
A new function for parietal epithelial cells: a second glomerular barrier
resolves10.1681/ASN.V134875
Differential Expression Patterns of Claudins, Tight Junction Membrane Proteins, in Mouse Nephron Segments
resolves10.1681/ASN.2007101087
Establishment of Conditionally Immortalized Mouse Glomerular Parietal Epithelial Cells in Culture
resolves10.1016/S0022-5320(76)80166-9
Junctions in developing human and rat kidney: A freeze—fracture study
resolves10.1007/s00441-010-1117-y
Novel expression of claudin-5 in glomerular podocytes
resolves10.1152/ajpregu.00862.2007
Claudin-6 localized in tight junctions of rat podocytes
resolves10.1152/ajprenal.1997.273.2.F179
Mechanisms of chloride transport in the proximal tubule
resolves10.1152/ajprenal.1983.244.5.F461
Sodium, bicarbonate, and chloride absorption by the proximal tubule
resolves10.1172/JCI112111
Active and passive components of chloride transport in the rat proximal convoluted tubule.
resolves10.1152/ajprenal.1984.247.5.F816
Axial heterogeneity in the rat proximal convoluted tubule. I. Bicarbonate, chloride, and water transport
resolves10.1152/ajprenal.1989.257.4.F658
Reflection coefficients and water permeability in rat proximal tubule
resolves10.1074/jbc.M608853200
Study of Claudin Function by RNA Interference
resolves10.1073/pnas.0912901107
Claudin-2–deficient mice are defective in the leaky and cation-selective paracellular permeability properties of renal proximal tubules
resolves10.1152/ajprenal.2000.278.6.F1030
Luminal hypotonicity in proximal tubules of aquaporin-1-knockout mice
resolves10.1242/jcs.060665
Claudin-2, a component of the tight junction, forms a paracellular water channel
resolves10.1073/pnas.95.16.9660
Defective proximal tubular fluid reabsorption in transgenic aquaporin-1 null mice
resolves10.1152/ajprenal.00138.2006
Two splice variants of claudin-10 in the kidney create paracellular pores with different ion selectivities
resolves10.1152/ajprenal.00063.2006
Claudins 6, 9, and 13 are developmentally expressed renal tight junction proteins
resolves10.1007/s00018-012-0949-x
Claudin-17 forms tight junction channels with distinct anion selectivity
resolves10.1091/mbc.E07-09-0973
Tight Junction Proteins Claudin-2 and -12 Are Critical for Vitamin D-dependent Ca <sup>2+</sup> Absorption between Enterocytes
resolves10.1152/ajplegacy.1964.206.4.687
Micropuncture study of hypertonic sodium chloride loading in the rat
resolves10.1681/ASN.V11101937
Inherited Disorders of Renal Magnesium Handling
resolves10.1111/j.1523-1755.2004.09105.x
Calcium and salinity sensing by the thick ascending limb: A journey from mammals to fish and back again
resolves10.1152/ajprenal.1981.241.4.F412
NaCl transport in mouse medullary thick ascending limbs. I. Functional nephron heterogeneity and ADH-stimulated NaCl cotransport
resolves10.1152/ajprenal.1981.241.4.F432
NaCl transport in mouse medullary thick ascending limbs. II. ADH enhancement of transcellular NaCl cotransport; origin of transepithelial voltage
resolves10.1152/physrev.1985.65.3.760
Ion transport mechanisms in thick ascending limb of Henle's loop of mammalian nephron.
resolves10.1086/508617
Mutations in the Tight-Junction Gene Claudin 19 (CLDN19) Are Associated with Renal Magnesium Wasting, Renal Failure, and Severe Ocular Involvement
resolves10.1172/JCI26323
Disease-associated mutations affect intracellular traffic and paracellular Mg2+ transport function of Claudin-16
resolves10.1074/jbc.M700632200
Transgenic RNAi Depletion of Claudin-16 and the Renal Handling of Magnesium
resolves10.1086/380418
A Novel Claudin 16 Mutation Associated with Childhood Hypercalciuria Abolishes Binding to ZO-1 and Results in Lysosomal Mistargeting
resolves10.1152/ajprenal.00608.2009
Physiology and pathophysiology of the calcium-sensing receptor in the kidney
resolves10.1152/ajprenal.1998.275.2.F198
Extracellular Ca<sup>2+</sup> decreases chloride reabsorption in rat CTAL by inhibiting cAMP pathway
resolves10.1007/s00424-008-0607-1
Thick ascending limb: the Na+:K+:2Cl− co-transporter, NKCC2, and the calcium-sensing receptor, CaSR
resolves10.1152/ajprenal.1997.273.3.F421
Phospholipase A2 is involved in mediating the effect of extracellular Ca2+ on apical K+ channels in rat TAL
resolves10.1159/000025892
Calcium–Sensing Receptor: Regulation of Electrolyte Transport in the Thick Ascending Limb of Henle's Loop
resolves10.1152/ajprenal.00346.2001
Calcium-sensing receptor regulation of PTH-dependent calcium absorption by mouse cortical ascending limbs
resolves10.1038/ng.404
Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density
resolves10.1038/emboj.2012.49
Claudin‐14 regulates renal Ca++ transport in response to CaSR signalling via a novel microRNA pathway
resolves10.1007/s00441-008-0621-9
Double gene deletion reveals lack of cooperation between claudin 11 and claudin 14 tight junction proteins
resolves10.1126/science.2063193
Blood Pressure Control—Special Role of the Kidneys and Body Fluids
resolves10.1016/S0092-8674(01)00241-0
Molecular Mechanisms of Human Hypertension
resolves10.1038/367463a0
Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits
resolves10.1152/ajprenal.1982.243.1.F81
Ionic conductive properties and electrophysiology of the rabbit cortical collecting tubule
resolves10.1007/BF01871637
Electrophysiological properties of cellular and paracellular conductive pathways of the rabbit cortical collecting duct
resolves10.1152/ajprenal.1984.247.2.F291
Microelectrode assessment of chloride-conductive properties of cortical collecting duct
resolves10.1242/jcs.02406
Overexpression of claudin-7 decreases the paracellular Cl– conductance and increases the paracellular Na+ conductance in LLC-PK1 cells
resolves10.1097/MNH.0b013e32833b7125
Claudin-16 and claudin-19 function in the thick ascending limb
resolves10.1152/ajpcell.00314.2005
Aldosterone and tight junctions: modulation of claudin-4 phosphorylation in renal collecting duct cells
resolves10.1073/pnas.1009399107
Claudin-4 forms paracellular chloride channel in the kidney and requires claudin-8 for tight junction localization
resolves10.1016/j.bbrc.2008.10.164
Na+ absorption defends from paracellular back-leakage by claudin-8 upregulation
resolves10.1073/pnas.0406172101
Paracellular Cl <sup>-</sup> permeability is regulated by WNK4 kinase: Insight into normal physiology and hypertension
resolves10.1016/j.bbrc.2006.08.101
Overexpression of human WNK1 increases paracellular chloride permeability and phosphorylation of claudin-4 in MDCKII cells
resolves10.1152/ajprenal.00450.2009
Renal salt wasting and chronic dehydration in claudin-7-deficient mice
resolves10.1042/BJ20051180
The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases
resolves10.1016/j.cmet.2007.03.009
Molecular Pathogenesis of Pseudohypoaldosteronism Type II: Generation and Analysis of a Wnk4 Knockin Mouse Model
resolves10.1152/physrev.1998.78.4.1165
Epithelial Transport in Polycystic Kidney Disease
resolves10.1073/pnas.0805761105
Hypertonic stress increases claudin-4 expression and tight junction integrity in association with MUPP1 in IMCD3 cells
resolves10.1074/jbc.M406331200
Association of Paracellin-1 with ZO-1 Augments the Reabsorption of Divalent Cations in Renal Epithelial Cells
resolves10.1152/ajpcell.00463.2003
Characterization of T-type calcium current and its contribution to electrical activity in rabbit urethra
resolves10.1016/j.ejcb.2010.01.003
The protoplasmic or exoplasmic face association of tight junction particles cannot predict paracellular permeability or heterotypic claudin compatibility
resolves10.1053/j.gastro.2010.08.006
Loss of Claudin-15, but Not Claudin-2, Causes Na+ Deficiency and Glucose Malabsorption in Mouse Small Intestine
resolves10.1016/j.bbamem.2010.07.014
Claudin-3 acts as a sealing component of the tight junction for ions of either charge and uncharged solutes
resolves10.1093/hmg/ddg210
Claudin 14 knockout mice, a model for autosomal recessive deafness DFNB29, are deaf due to cochlear hair cell degeneration
resolves10.1152/ajpgi.00158.2007
Claudin-18: a dominant tight junction protein in Barrett's esophagus and likely contributor to its acid resistance
resolves10.4161/org.19808
Lecture
The 5 references without a DOI — listed, not checked
no DOI — not checkedB28
no DOI — not checkedB56
no DOI — not checkedB57
no DOI — not checkedB58
no DOI — not checkedB59
What this badge says. CiteStamped means the CHECKABLE references of this work were clean at the dated check: each resolved to a known work in a public registry, and none carried a retraction notice at that time. It says nothing about the quality, findings, or importance of the work itself, and nothing about references deposited without a DOI.

checked 2026-07-23 — re-checked daily as this page is visited; titles and statuses come from Crossref and DataCite and are not part of the signed record

Embed this badge

Both snippets point at the live badge image and link back to this page. The badge re-renders from the daily check, so an embed never goes stale by more than a day of visits.

<a href="https://citestamp.com/citestamped/10.1146/annurev-physiol-030212-183705"><img src="https://citestamp.com/citestamped/10.1146/annurev-physiol-030212-183705/badge.svg" alt="CiteStamped reference-health badge" width="460" height="64"></a>
[![CiteStamped reference-health badge](https://citestamp.com/citestamped/10.1146/annurev-physiol-030212-183705/badge.svg)](https://citestamp.com/citestamped/10.1146/annurev-physiol-030212-183705)