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Structural Basis for the Binding of the Anticancer Compound 6-(7-Nitro-2,1,3-Benzoxadiazol-4-Ylthio)Hexanol to Human Glutathione <i>S</i>-Transferases

https://doi.org/10.1158/0008-5472.can-09-1314
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40/40 checkable references clean · checked 2026-07-22

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

3 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 40 checked references that resolve
resolves10.1016/j.ctrv.2008.03.002
Combined action and regulation of phase II enzymes and multidrug resistance proteins in multidrug resistance in cancer
resolves10.1038/sj.onc.1206940
The role of glutathione-S-transferase in anti-cancer drug resistance
resolves10.1146/annurev.pharmtox.45.120403.095857
GLUTATHIONE TRANSFERASES
resolves10.1016/j.sbi.2005.10.005
Glutathione transferases: new functions
resolves10.1042/bj3600001
Structure, function and evolution of glutathione transferases: implications for classification of non-mammalian members of an ancient enzyme superfamily
resolves10.1159/000196451
Glutathione S Transferase Pi Is a Powerful Indicator in Chemotherapy of Human Lung Squamous-Cell Carcinoma
resolves10.1007/BF03179798
P-glycoprotein, glutathione and glutathione S-transferase increase in a colon carcinoma
resolves10.1002/1097-0142(19940815)74:4<1230::AID-CNCR2820740409>3.0.CO;2-0
Expression of glutathione s-transferasepi and sensitivity of human gastric cancer cells to cisplatin
resolves10.1038/bjc.1993.321
Glutathione S-transferase expression in benign and malignant ovarian tumours
resolves10.1111/j.1600-0714.1994.tb00260.x
Increase in placental glutathione S‐transferase in human oral epithelial dysplastic lesions and squamous cell carcinomas
resolves10.1038/bjc.1993.299
Immunohistochemical detection of P-glycoprotein and GSTP1-1 in testis cancer
resolves10.1093/emboj/18.5.1321
Regulation of JNK signaling by GSTp
resolves10.1074/jbc.M101355200
Glutathione S-transferase P1–1 (GSTP1–1) Inhibits c-Jun N-terminal Kinase (JNK1) Signaling through Interaction with the C Terminus
resolves10.1007/s10495-007-0053-0
Conformational change in the active center region of GST P1-1, due to binding of a synthetic conjugate of DXR with GSH, enhanced JNK-mediated apoptosis
resolves10.1007/s00018-005-4524-6
The chemistry and biology of inhibitors and pro-drugs targeted to glutathione S-transferases
resolves10.1016/j.bcp.2006.09.027
Redox in redux: Emergent roles for glutathione S-transferase P (GSTP) in regulation of cell signaling and S-glutathionylation
resolves10.1074/jbc.M503295200
7-Nitro-2,1,3-benzoxadiazole Derivatives, a New Class of Suicide Inhibitors for Glutathione S-Transferases
resolves10.1158/0008-5472.CAN-04-3903
Proapoptotic Activity of New Glutathione <i>S</i>-Transferase Inhibitors
resolves10.1074/jbc.M604372200
A Strong Glutathione S-Transferase Inhibitor Overcomes the P-glycoprotein-mediated Resistance in Tumor Cells
resolves10.1007/s00280-009-0960-6
The glutathione S-transferase inhibitor 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol overcomes the MDR1-P-glycoprotein and MRP1-mediated multidrug resistance in acute myeloid leukemia cells
resolves10.1158/1535-7163.MCT-07-0487
6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol, a specific glutathione <i>S</i>-transferase inhibitor, overcomes the multidrug resistance (MDR)-associated protein 1–mediated MDR in small cell lung cancer
resolves10.1158/0008-5472.CAN-07-5840
Overcoming Glutathione <i>S</i> -Transferase P1–Related Cisplatin Resistance in Osteosarcoma
resolves10.1016/j.coph.2007.06.009
Genetic polymorphism and function of glutathione S-transferases in tumor drug resistance
resolves10.1006/prep.1995.1076
Cytoplasmic and Periplasmic Production of Human Placental Glutathione Transferase in Escherichia coli
resolves10.1074/jbc.270.3.1249
Site-directed Mutagenesis of Human Glutathione Transferase P1-1
resolves10.1016/S0076-6879(97)76066-X
[20] Processing of X-ray diffraction data collected in oscillation mode
resolves10.1107/S0907444900013780
An approach to multi-copy search in molecular replacement
resolves10.1006/jmbi.1994.1336
Crystal Structure of Human Class mu Glutathione Transferase GSTM2-2
resolves10.1107/S0907444996012255
Refinement of Macromolecular Structures by the Maximum-Likelihood Method
resolves10.1107/S0907444904019158
<i>Coot</i>: model-building tools for molecular graphics
resolves10.1006/jmbi.1997.1364
The structures of human glutathione transferase P1-1 in complex with glutathione and various inhibitors at high resolution
resolves10.1107/S0021889892009944
PROCHECK: a program to check the stereochemical quality of protein structures
resolves10.1016/S0076-6879(81)77053-8
[51] Assays for differentiation of glutathione S-Transferases
resolves10.1074/jbc.271.27.16187
Structural Flexibility Modulates the Activity of Human Glutathione Transferase P1-1
resolves10.1074/jbc.271.27.16193
Structural Flexibility Modulates the Activity of Human Glutathione Transferase P1-1
resolves10.1006/jmbi.1998.1708
Structure-activity relationships and thermal stability of human glutathione transferase P1-1 governed by the H-site residue 105
resolves10.1021/bi962316i
The Three-Dimensional Structure of the Human Pi Class Glutathione Transferase P1-1 in Complex with the Inhibitor Ethacrynic Acid and Its Glutathione Conjugate<sup>,</sup>
resolves10.1016/j.jmb.2008.04.066
The Anti-cancer Drug Chlorambucil as a Substrate for the Human Polymorphic Enzyme Glutathione Transferase P1-1: Kinetic Properties and Crystallographic Characterisation of Allelic Variants
resolves10.1016/0167-4838(93)90245-M
Interactions of glutathione S-transferase-π with ethacrynic acid and its glutathione conjugate
resolves10.1016/S0006-2952(99)00142-2
Characterization of a chlorambucil-resistant human ovarian carcinoma cell line overexpressing glutathione S-transferase μ
The 3 references without a DOI — listed, not checked
no DOI — not checkedGrignon DJ, Abdel-Malak M, Mertens WC, Sakr WA, Shepherd RR. Glutathione S-transferase expression in renal cell carcinoma: a new marker of differentiation. Mod Pathol 1994; 7: 186–9.
no DOI — not checkedBan N, Takahashi Y, Takayama T, et al. Transfection of glutathione S-transferase (GST)-pi antisense complementary DNA increases the sensitivity of a colon cancer cell line to adriamycin, cisplatin, melphalan, and etoposide. Cancer Res 1996; 56: 3577–82.
no DOI — not checkedAdler V, Pincus MR. Effector peptides from glutathione-S-transferase-pi affect the activation of jun by jun-N-terminal kinase. Ann Clin Lab Sci 2004; 34: 35–46.
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