Reference health
Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth
60/60 checkable references clean · checked 2026-07-23
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
4 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 60 checked references that resolve
resolves10.1634/theoncologist.13-S3-21
Hypoxia and Aggressive Tumor Phenotype: Implications for Therapy and Prognosis
resolves10.1186/s12943-019-1089-9
Role of hypoxia in cancer therapy by regulating the tumor microenvironment
resolves10.2147/HP.S93413
The role of hypoxia in cancer progression, angiogenesis, metastasis, and resistance to therapy
resolves10.1016/j.ccell.2014.12.002
Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress
resolves10.1016/j.molcel.2017.04.026
Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy
resolves10.1074/jbc.M004160200
Molecular Characterization of Human Acetyl-CoA Synthetase, an Enzyme Regulated by Sterol Regulatory Element-binding Proteins
resolves10.1002/jcp.25954
Acyl‐CoA synthetase short‐chain family member 2 (ACSS2) is regulated by SREBP‐1 and plays a role in fatty acid synthesis in caprine mammary epithelial cells
resolves10.1111/j.1349-7006.2009.01099.x
Cytosolic acetyl‐CoA synthetase affected tumor cell survival under hypoxia: the possible function in tumor acetyl‐CoA/acetate metabolism
resolves10.1016/j.celrep.2016.12.055
Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation
resolves10.1016/j.cmet.2006.02.002
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
resolves10.1002/nbm.2794
Metabolism of [U‐<sup>13</sup>C]glucose in human brain tumors <i>in vivo</i>
resolves10.1016/j.cell.2014.11.025
Acetate Is a Bioenergetic Substrate for Human Glioblastoma and Brain Metastases
resolves10.1371/journal.pone.0190241
Coordinate regulation of stress signaling and epigenetic events by Acss2 and HIF-2 in cancer cells
resolves10.1371/journal.pone.0116515
The Acetate/ACSS2 Switch Regulates HIF-2 Stress Signaling in the Tumor Cell Microenvironment
resolves10.1074/jbc.M115.712166
Glucose-independent Acetate Metabolism Promotes Melanoma Cell Survival and Tumor Growth
resolves10.1158/0008-5472.CAN-16-1308
Trametinib Drives T-cell–Dependent Control of KRAS-Mutated Tumors by Inhibiting Pathological Myelopoiesis
resolves10.1016/j.ccell.2014.11.009
Microbially Driven TLR5-Dependent Signaling Governs Distal Malignant Progression through Tumor-Promoting Inflammation
resolves10.1038/oncsis.2016.65
Constitutively activated PI3K accelerates tumor initiation and modifies histopathology of breast cancer
resolves10.1093/nar/gkr366
SwissDock, a protein-small molecule docking web service based on EADock DSS
resolves10.1021/bi0271603
The 1.75 Å Crystal Structure of Acetyl-CoA Synthetase Bound to Adenosine-5‘-propylphosphate and Coenzyme A
resolves10.1107/S0907444909052925
<i>PHENIX</i>: a comprehensive Python-based system for macromolecular structure solution
resolves10.1186/1471-2105-12-323
RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
resolves10.1186/s13059-014-0550-8
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
resolves10.1038/nature10983
The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
resolves10.1158/2159-8290.CD-12-0095
The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data
resolves10.1126/scisignal.2004088
Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
resolves10.1038/ncb3272
Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma
resolves10.1126/sciadv.aau7314
Improving the metabolic fidelity of cancer models with a physiological cell culture medium
resolves10.1038/nature22405
Acetyl-CoA synthetase regulates histone acetylation and hippocampal memory
resolves10.1074/jbc.M008782200
Acetyl-CoA Synthetase 2, a Mitochondrial Matrix Enzyme Involved in the Oxidation of Acetate
resolves10.1158/1078-0432.CCR-06-3045
Triple-Negative Breast Cancer: Clinical Features and Patterns of Recurrence
resolves10.1016/j.celrep.2013.08.022
Endocrine-Therapy-Resistant ESR1 Variants Revealed by Genomic Characterization of Breast-Cancer-Derived Xenografts
resolves10.1038/ncomms11960
Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia
resolves10.1073/pnas.1806635115
ACSS2 promotes systemic fat storage and utilization through selective regulation of genes involved in lipid metabolism
resolves10.1158/0008-5472.CAN-09-3871
<i>De novo</i>
Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation
resolves10.1186/s40170-016-0146-8
Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments
resolves10.1016/j.cell.2020.03.029
Genetic Screen for Cell Fitness in High or Low Oxygen Highlights Mitochondrial and Lipid Metabolism
resolves10.1186/2049-3002-2-23
Quantitative analysis of acetyl-CoA production in hypoxic cancer cells reveals substantial contribution from acetate
resolves10.1016/j.cell.2018.08.040
Acetate Production from Glucose and Coupling to Mitochondrial Metabolism in Mammals
resolves10.2967/jnumed.113.134437
Late Imaging with [1-<sup>11</sup>C]Acetate Improves Detection of Tumor Fatty Acid Synthesis with PET
resolves10.1126/scisignal.2000446
EGFR Signaling Through an Akt-SREBP-1–Dependent, Rapamycin-Resistant Pathway Sensitizes Glioblastomas to Antilipogenic Therapy
resolves10.1016/j.molcel.2010.06.022
Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1
resolves10.1007/s00259-018-3948-9
The roles of 11C-acetate PET/CT in predicting tumor differentiation and survival in patients with cerebral glioma
resolves10.1158/1078-0432.CCR-15-2134
Evaluating Acetate Metabolism for Imaging and Targeting in Multiple Myeloma
resolves10.2967/jnumed.117.199869
Imaging Cancer Metabolism: Underlying Biology and Emerging Strategies
resolves10.1016/j.molcel.2011.05.004
Acetyl-CoA Induces Cell Growth and Proliferation by Promoting the Acetylation of Histones at Growth Genes
The 4 references without a DOI — listed, not checked
no DOI — not checkedInitiation of metastatic breast carcinoma by targeting of the ductal epithelium with adenovirus-cre: a novel transgenic mouse model of breast cancer
no DOI — not checkedMolecular cloning of rat acss3 and characterization of mammalian propionyl-CoA synthetase in the liver mitochondrial matrix
no DOI — not checkedTranscriptome analysis of HER2 reveals a molecular connection to fatty acid synthesis
no DOI — not checkedDetection of bone metastases using 11C-acetate PET in patients with prostate cancer with biochemical recurrence
What this badge says. CiteStamped means the CHECKABLE references of this
work were clean at the dated check: each resolved to a known work in a public registry, and none
carried a retraction notice at that time. It says nothing about the quality, findings,
or importance of the work itself, and nothing about references deposited without a DOI.
checked 2026-07-23 — re-checked daily as this page is visited; titles and statuses come from Crossref and DataCite and are not part of the signed record
Embed this badge
Both snippets point at the live badge image and link back to this page. The badge re-renders from the daily check, so an embed never goes stale by more than a day of visits.
<a href="https://citestamp.com/citestamped/10.1158/0008-5472.can-20-1847"><img src="https://citestamp.com/citestamped/10.1158/0008-5472.can-20-1847/badge.svg" alt="CiteStamped reference-health badge" width="460" height="64"></a>
[](https://citestamp.com/citestamped/10.1158/0008-5472.can-20-1847)