Reference health
Mitochondria are the primary target in isothiocyanate-induced apoptosis in human bladder cancer cells
44/44 checkable references clean · checked 2026-07-23
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
11 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 44 checked references that resolve
resolves10.2174/1389200023337496
Isothiocyanates as Cancer Chemopreventive Agents: Their Biological Activities and Metabolism in Rodents and Humans
resolves10.3892/ijo.20.3.631
Sulforaphane and its metabolite mediate growth arrest and apoptosis in human prostate cancer cells
resolves10.1093/carcin/23.4.581
Growth inhibition, cell-cycle arrest and apoptosis in human T-cell leukemia by the isothiocyanate sulforaphane
resolves10.1016/S0006-2952(00)00319-1
Studies on the mechanism of the inhibition of human leukaemia cell growth by dietary isothiocyanates and their cysteine adducts in vitro
resolves10.1097/00001813-199802000-00005
Selective cytostatic and cytotoxic effects of glucosinolates hydrolysis products on human colon cancer cells in viro
resolves10.1093/carcin/bgg023
Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits proliferation of human prostate cancer cells by causing G2/M arrest and inducing apoptosis
resolves10.1093/carcin/14.10.2079
Allyl isothiocyanate is selectively toxic to transformed cells of the human colorectal tumour line HT29
resolves10.3109/00498258809041680
Studies on the metabolism and excretion of benzyl isothiocyanate in man
resolves10.1016/S0009-8981(01)00727-6
Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: pharmacokinetics of broccoli sprout isothiocyanates in humans
resolves10.1093/jn/134.8.2004
Dietary Isothiocyanates Inhibit the Growth of Human Bladder Carcinoma Cells
resolves10.1074/jbc.M109760200
Involvement of the Mitochondrial Death Pathway in Chemopreventive Benzyl Isothiocyanate-induced Apoptosis
resolves10.1093/carcin/21.6.1175
Role of glutathione in the accumulation of anticarcinogenic isothiocyanates and their glutathione conjugates by murine hepatoma cells
resolves10.1093/carcin/22.3.425
Molecular mechanism of rapid cellular accumulation of anticarcinogenic isothiocyanates
resolves10.1016/S0092-8674(00)80085-9
Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c
resolves10.1016/0005-2728(86)90112-X
Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties
resolves10.1042/bj3110453
Isothiocyanates as substrates for human glutathione transferases: structure-activity studies
resolves10.1006/excr.1999.4527
Collapse of the Inner Mitochondrial Transmembrane Potential Is Not Required for Apoptosis of HL60 Cells
resolves10.1016/S0021-9258(18)83116-7
Cyclosporin A is a potent inhibitor of the inner membrane permeability transition in liver mitochondria
resolves10.1042/bj2680153
Inhibition of Ca2+-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl-prolyl <i>cis-trans</i> isomerase and preventing it interacting with the adenine nucleotide translocase
resolves10.1073/pnas.95.25.14681
Bax interacts with the permeability transition pore to induce permeability transition and cytochrome
<i>c</i>
release in isolated mitochondria
resolves10.1080/10715760310001626266
Oxidative Stress Underlies the Mechanism for Ca<sup>2+</sup>-induced Permeability Transition of Mitochondria
resolves10.1074/jbc.M303808200
Cyclosporin A-insensitive Permeability Transition in Brain Mitochondria
resolves10.1016/S0300-483X(03)00327-5
Cadmium directly induced the opening of membrane permeability pore of mitochondria which possibly involved in cadmium-triggered apoptosis
resolves10.1158/0008-5472.CAN-04-3616
Bax and Bak Are Required for Apoptosis Induction by Sulforaphane, a Cruciferous Vegetable–Derived Cancer Chemopreventive Agent
resolves10.1054/bjoc.2000.1636
Signal transduction activated by the cancer chemopreventive isothiocyanates: cleavage of BID protein, tyrosine phosphorylation and activation of JNK
resolves10.1158/0008-5472.CAN-03-2296
A Link between Benzyl Isothiocyanate-Induced Cell Cycle Arrest and Apoptosis: Involvement of Mitogen-Activated Protein Kinases in the Bcl-2 Phosphorylation
resolves10.1016/j.biocel.2004.05.018
β-Phenylethyl isothiocyanate mediated apoptosis; contribution of Bax and the mitochondrial death pathway
resolves10.1016/S0014-5793(01)02693-X
The protonophore CCCP induces mitochondrial permeability transition without cytochrome <i>c</i> release in human osteosarcoma cells
resolves10.1042/bj3070099
Contribution of the mitochondrial permeability transition to lethal injury after exposure of hepatocytes to <i>t</i>-butylhydroperoxide
resolves10.1007/s00018-003-3150-4
?-phenylethyl isothiocyanate-mediated apoptosis in hepatoma HepG2 cells
resolves10.1006/bbrc.2001.4531
Reactive Oxygen Species-Related Induction of Multidrug Resistance-Associated Protein 2 Expression in Primary Hepatocytes Exposed to Sulforaphane
resolves10.1016/0003-9861(85)90293-0
Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria
resolves10.1016/S0300-483X(03)00163-X
Histological changes and impairment of liver mitochondrial bioenergetics after long-term treatment with α-naphthyl-isothiocyanate (ANIT)
The 11 references without a DOI — listed, not checked
no DOI — not checkedZhang Y, Talalay P. Anticarcinogenic activities of organic isothiocyanates: chemistry and mechanisms. Cancer Res 1994;54:1976–81s.
no DOI — not checkedHuang C, Ma WY, Li JX, Hecht SS, Dong ZG. Essential role of p53 in phenethyl isothiocyanate-induced apoptosis. Cancer Res 1998;58:4102–6.
no DOI — not checkedGamet-Payrastre L, Li P, Lumeau S, et al. Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cells. Cancer Res 2000;60:1426–33.
no DOI — not checkedZhang Y, Tang L, Gonzalez V. Selected isothiocyanates rapidly induce growth inhibition of cancer cells. Mol Cancer Ther 2003;2:1045–52.
no DOI — not checkedChung FL, Morse MA, Eklind KI, Lewis J. Quantification of human uptake of the anticarcinogen phenethyl isothiocyanate after a watercress meal. Cancer Epidemiol Biomarkers Prev 1992;1:383–8.
no DOI — not checkedJiao D, Ho CT, Fioles P, Chung FL. Identification and quantification of the N-acetylcysteine conjugate of allyl isothiocyanate in human urine after ingestion of mustard. Cancer Epidemiol Biomarkers Prev 1994;3:487–92.
no DOI — not checkedShapiro TA, Fahey JW, Wade KL, Stephenson KK, Talalay P. Chemoprotective glucosinolates and isothiocyanates of broccoli sprouts: metabolism and excretion in humans. Cancer Epidemiol Biomarkers Prev 2001;10:501–8.
no DOI — not checkedYu R, Mandlekar S, Harvey KJ, Ucker DS, Kong A-NT. Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity. Cancer Res 1998;58:402–8.
no DOI — not checkedZhang Y, Talalay P. Mechanism of differential protencies of isothiocyanates as inducers of anticarcinogenic phase 2 enzymes. Cancer Res 1998;58:4632–9.
no DOI — not checkedHenderson PJ, Lardy HA. An inhibitor of the adenine nucleotide translocase of mitochondria. J Biol Chem 1970;245:1319–26.
no DOI — not checkedNakamura Y, Ohigashi H, Masuda S, et al. Redox regulation of glutathione S-transferase induction by benzyl isothiocyanate: correlation of enzyme induction with the formation of reactive oxygen intermediates. Cancer Res 2000;60:219–25.
What this badge says. CiteStamped means the CHECKABLE references of this
work were clean at the dated check: each resolved to a known work in a public registry, and none
carried a retraction notice at that time. It says nothing about the quality, findings,
or importance of the work itself, and nothing about references deposited without a DOI.
checked 2026-07-23 — re-checked daily as this page is visited; titles and statuses come from Crossref and DataCite and are not part of the signed record
Embed this badge
Both snippets point at the live badge image and link back to this page. The badge re-renders from the daily check, so an embed never goes stale by more than a day of visits.
<a href="https://citestamp.com/citestamped/10.1158/1535-7163.mct-05-0041"><img src="https://citestamp.com/citestamped/10.1158/1535-7163.mct-05-0041/badge.svg" alt="CiteStamped reference-health badge" width="460" height="64"></a>
[](https://citestamp.com/citestamped/10.1158/1535-7163.mct-05-0041)