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The IKZF1–IRF4/IRF5 Axis Controls Polarization of Myeloma-Associated Macrophages
58/58 checkable references clean · checked 2026-07-23
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
The 58 checked references that resolve
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Macrophages are an abundant component of myeloma microenvironment and protect myeloma cells from chemotherapy drug–induced apoptosis
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Tumor-promoting immune-suppressive myeloid-derived suppressor cells in the multiple myeloma microenvironment in humans
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Macrophages and mesenchymal stromal cells support survival and proliferation of multiple myeloma cells
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Dysregulated IL-18 Is a Key Driver of Immunosuppression and a Possible Therapeutic Target in the Multiple Myeloma Microenvironment
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Tumor-associated macrophages and extracellular matrix metalloproteinase inducer in prognosis of multiple myeloma
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Evaluation of the potential therapeutic benefits of macrophage reprogramming in multiple myeloma
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Anti-CD47 antibodies promote phagocytosis and inhibit the growth of human myeloma cells
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Antibody-mediated phagocytosis contributes to the anti-tumor activity of the therapeutic antibody daratumumab in lymphoma and multiple myeloma
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Antibody-Dependent Cellular Phagocytosis by Macrophages is a Novel Mechanism of Action of Elotuzumab
resolves10.1038/s41375-018-0114-0
Lenalidomide enhances MOR202-dependent macrophage-mediated effector functions via the vitamin D pathway
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Elotuzumab in combination with lenalidomide and dexamethasone in patients with relapsed multiple myeloma: final phase 2 results from the randomised, open-label, phase 1b–2 dose-escalation study
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Transcriptional Profiling of the Human Monocyte-to-Macrophage Differentiation and Polarization: New Molecules and Patterns of Gene Expression
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High numbers of CD163+ tumor-associated macrophages correlate with poor prognosis in multiple myeloma patients receiving bortezomib-based regimens
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High level of interleukin-10 in serum predicts poor prognosis in multiple myeloma
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Lenalidomide Causes Selective Degradation of IKZF1 and IKZF3 in Multiple Myeloma Cells
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Awakening lineage potential by Ikaros-mediated transcriptional priming
resolves10.1073/pnas.0400983101
Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria
resolves10.1182/blood-2003-06-1984
BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone
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SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin
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CD44 Antibody Inhibition of Macrophage Phagocytosis Targets Fcγ Receptor– and Complement Receptor 3–Dependent Mechanisms
resolves10.1182/blood-2011-08-372425
Human CD300a binds to phosphatidylethanolamine and phosphatidylserine, and modulates the phagocytosis of dead cells
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The CD47–SIRPα pathway in cancer immune evasion and potential therapeutic implications
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M2 Macrophages Phagocytose Rituximab-Opsonized Leukemic Targets More Efficiently than M1 Cells In Vitro
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Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines
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The PD-1/PD-L1 axis contributes to immune metabolic dysfunctions of monocytes in chronic lymphocytic leukemia
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Lenalidomide downregulates the cell survival factor, interferon regulatory factor‐4, providing a potential mechanistic link for predicting response
resolves10.1038/ni.1920
The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection
resolves10.1182/blood-2015-02-628669
CC-122, a pleiotropic pathway modifier, mimics an interferon response and has antitumor activity in DLBCL
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TNF-Mediated Restriction of Arginase 1 Expression in Myeloid Cells Triggers Type 2 NO Synthase Activity at the Site of Infection
resolves10.1182/blood-2006-07-037754
Interleukin 2 gene transcription is regulated by Ikaros-induced changes in histone acetylation in anergic T cells
resolves10.1038/leu.2015.331
Epigenetic regulation of gene expression by Ikaros, HDAC1 and Casein Kinase II in leukemia
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Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS
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Lenalidomide regulates CNS autoimmunity by promoting M2 macrophages polarization
resolves10.1182/blood-2018-05-852798
Crbn
I391V is sufficient to confer in vivo sensitivity to thalidomide and its derivatives in mice
resolves10.1158/2326-6066.CIR-15-0025-T
Tumoricidal Effects of Macrophage-Activating Immunotherapy in a Murine Model of Relapsed/Refractory Multiple Myeloma
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Lenalidomide Enhances Immune Checkpoint Blockade-Induced Immune Response in Multiple Myeloma
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Randomized Trial of Lenalidomide Alone Versus Lenalidomide Plus Rituximab in Patients With Recurrent Follicular Lymphoma: CALGB 50401 (Alliance)
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Transcriptional regulation of macrophage polarization: enabling diversity with identity
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Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
resolves10.1101/gad.297002.117
The making of a lymphocyte: the choice among disparate cell fates and the IKAROS enigma
resolves10.1016/j.immuni.2009.01.014
Genome-wide Lineage-Specific Transcriptional Networks Underscore Ikaros-Dependent Lymphoid Priming in Hematopoietic Stem Cells
resolves10.4049/jimmunol.1800158
Dual Roles for Ikaros in Regulation of Macrophage Chromatin State and Inflammatory Gene Expression
resolves10.1111/imr.12209
Mi‐2/Nu<scp>RD</scp> chromatin remodeling complexes regulate B and T‐lymphocyte development and function
resolves10.1007/s00296-010-1576-1
Down-regulated expression of IKZF1 mRNA in peripheral blood mononuclear cells from patients with systemic lupus erythematosus
resolves10.1038/ng.472
Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus
resolves10.1080/2162402X.2015.1016699
Ikaros deficiency in host hematopoietic cells separates GVL from GVHD after experimental allogeneic hematopoietic cell transplantation
resolves10.1038/s41409-019-0449-9
G-CSF-induced macrophage polarization and mobilization may prevent acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
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