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Aldehyde dehydrogenase 1 defines and protects a nigrostriatal dopaminergic neuron subpopulation

https://doi.org/10.1172/jci72176
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Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

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The 43 checked references that resolve
resolves10.1111/j.1600-0404.1989.tb01778.x
Selective vulnerability of pigmented dopaminergic neurons in Parkinson's disease
resolves10.1093/brain/114.5.2283
AGEING AND PARKINSON'S DISEASE: SUBSTANTIA NIGRA REGIONAL SELECTIVITY
resolves10.1093/brain/122.8.1437
The substantia nigra of the human brain
resolves10.1038/42166
α-Synuclein in Lewy bodies
resolves10.1126/science.276.5321.2045
Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease
resolves10.1126/science.1090278
α-Synuclein Locus Triplication Causes Parkinson's Disease
resolves10.1038/ng.487
Genome-wide association study reveals genetic risk underlying Parkinson's disease
resolves10.1038/ng.485
Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease
resolves10.1523/JNEUROSCI.1731-12.2012
Conditional Expression of Parkinson's Disease-Related Mutant  -Synuclein in the Midbrain Dopaminergic Neurons Causes Progressive Neurodegeneration and Degradation of Transcription Factor Nuclear Receptor Related 1
resolves10.1073/pnas.91.16.7772
High levels of a retinoic acid-generating dehydrogenase in the meso-telencephalic dopamine system.
resolves10.1124/pr.59.2.1
Neurotoxicity and Metabolism of the Catecholamine-Derived 3,4-Dihydroxyphenylacetaldehyde and 3,4-Dihydroxyphenylglycolaldehyde: The Role of Aldehyde Dehydrogenase
resolves10.1021/tx9000557
Protein Reactivity of 3,4-Dihydroxyphenylacetaldehyde, a Toxic Dopamine Metabolite, Is Dependent on Both the Aldehyde and the Catechol
resolves10.1073/pnas.1220399110
Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease
resolves10.1016/j.brainres.2011.06.051
Functional significance of aldehyde dehydrogenase ALDH1A1 to the nigrostriatal dopamine system
resolves10.1371/journal.pone.0031522
Neurodegeneration and Motor Dysfunction in Mice Lacking Cytosolic and Mitochondrial Aldehyde Dehydrogenases: Implications for Parkinson's Disease
resolves10.1126/science.1063522
Kinetic Stabilization of the α-Synuclein Protofibril by a Dopamine-α-Synuclein Adduct
resolves10.1007/s00401-007-0303-9
Aggregation of α-synuclein by DOPAL, the monoamine oxidase metabolite of dopamine
resolves10.1172/JCI15777
Misfolded proteinase K–resistant hyperphosphorylated α-synuclein in aged transgenic mice with locomotor deterioration and in human α-synucleinopathies
resolves10.1523/JNEUROSCI.0285-07.2007
Aggregated α-Synuclein Mediates Dopaminergic Neurotoxicity<i>In Vivo</i>
resolves10.1016/j.cell.2012.03.037
Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein
resolves10.1016/j.nbd.2003.09.001
ALDH1 mRNA: presence in human dopamine neurons and decreases in substantia nigra in Parkinson's disease and in the ventral tegmental area in schizophrenia
resolves10.1523/JNEUROSCI.04-01-00111.1984
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. III. Immunocytochemical localization
resolves10.1128/MCB.23.13.4637-4648.2003
Targeted Disruption of <i>Aldh1a1</i> (<i>Raldh1</i>) Provides Evidence for a Complex Mechanism of Retinoic Acid Synthesis in the Developing Retina
resolves10.1016/j.cbi.2011.01.006
Dopamine-derived biological reactive intermediates and protein modifications: Implications for Parkinson's disease
resolves10.1007/s12031-011-9688-y
Modulation of Aldehyde Dehydrogenase Activity Affects (±)-4-Hydroxy-2E-nonenal (HNE) Toxicity and HNE–Protein Adduct Levels in PC12 Cells
resolves10.1523/JNEUROSCI.22-07-02637.2002
Caspase Inhibitors Attenuate 1-Methyl-4-Phenylpyridinium Toxicity in Primary Cultures of Mesencephalic Dopaminergic Neurons
resolves10.1523/JNEUROSCI.15-05-03318.1995
Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation
resolves10.1083/jcb.134.3.757
Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: evidence for cell cycle-independent toxicity.
resolves10.1016/j.neuron.2009.11.006
Leucine-Rich Repeat Kinase 2 Regulates the Progression of Neuropathology Induced by Parkinson's-Disease-Related Mutant α-synuclein
resolves10.1002/mds.25095
Neuronal vulnerability, pathogenesis, and Parkinson's disease
resolves10.1016/S1474-4422(07)70246-6
Calcium, ageing, and neuronal vulnerability in Parkinson's disease
resolves10.1074/jbc.R112.410530
Calcium, Bioenergetics, and Neuronal Vulnerability in Parkinson's Disease
resolves10.1038/nm1201-1280
α-synuclein and cytosolic dopamine: Stabilizing a bad situation
resolves10.1111/jnc.12345
Determinants of buildup of the toxic dopamine metabolite<scp>DOPAL</scp>in Parkinson's disease
resolves10.1371/journal.pone.0011464
A53T-Alpha-Synuclein Overexpression Impairs Dopamine Signaling and Striatal Synaptic Plasticity in Old Mice
resolves10.1002/jnr.22611
Elevated tonic extracellular dopamine concentration and altered dopamine modulation of synaptic activity precede dopamine loss in the striatum of mice overexpressing human α‐synuclein
resolves10.1242/dev.02865
Retinoic acid counteracts developmental defects in the substantia nigra caused by Pitx3 deficiency
resolves10.1111/jnc.12160
The transcription factor Pitx3 is expressed selectively in midbrain dopaminergic neurons susceptible to neurodegenerative stress
resolves10.1126/science.274.5293.1678
Control of Memory Formation Through Regulated Expression of a CaMKII Transgene
resolves10.1007/s10561-008-9067-2
The Sun Health Research Institute Brain Donation Program: Description and Eexperience, 1987–2007
resolves10.1038/nm1314
Dopamine covalently modifies and functionally inactivates parkin
resolves10.1016/j.nbd.2007.11.011
Progressive behavioral deficits in DJ-1-deficient mice are associated with normal nigrostriatal function
resolves10.1523/JNEUROSCI.2795-06.2006
Intracranial Adeno-Associated Virus-Mediated Delivery of Anti-Pan Amyloid β, Amyloid β40, and Amyloid β42 Single-Chain Variable Fragments Attenuates Plaque Pathology in Amyloid Precursor Protein Mice
The 3 references without a DOI — listed, not checked
no DOI — not checkedB1
no DOI — not checkedFranklin KBJ, Paxinos G. The Mouse Brain in Stereotaxic Coordinates. 3rd ed. Waltham, Massachusetts, USA: Academic Press; 2008.
no DOI — not checkedMai JK, Paxinos G, Voss T. Atlas Of The Human Brain. 3rd ed. Waltham, Massachusetts, USA: Academic Press; 2007.
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