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Treatment of Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia

https://doi.org/10.1182/asheducation-2005.1.118
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33/33 checkable references clean · checked 2026-07-25

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

7 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 33 checked references that resolve
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Philadelphia Chromosome–Positive Acute Lymphocytic Leukemia
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Recent approaches in acute lymphoblastic leukemia in adults
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Leading prognostic relevance of the BCR-ABL translocation in adult acute B-lineage lymphoblastic leukemia: a prospective study of the German Multicenter Trial Group and confirmed polymerase chain reaction analysis
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Outcome of treatment in adults with Philadelphia chromosome-positive acute lymphoblastic leukemia---results of the prospective multicenter LALA-94 trial
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Results of Treatment With Hyper-CVAD, a Dose-Intensive Regimen, in Adult Acute Lymphocytic Leukemia
resolves10.1038/sj.bmt.1703899
Bone marrow transplant in Ph+ ALL patients
resolves10.1182/blood.V97.6.1572
Unrelated marrow transplantation for adult patients with poor-risk acute lymphoblastic leukemia: strong graft-versus-leukemia effect and risk factors determining outcome
resolves10.1038/nm0596-561
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr–Abl positive cells
resolves10.1056/NEJM200104053441402
Activity of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in the Blast Crisis of Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia with the Philadelphia Chromosome
resolves10.1182/blood-2001-12-0181
A phase 2 study of imatinib in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoid leukemias
resolves10.1182/blood-2003-01-0154
Early prediction of response in patients with relapsed or refractory Philadelphia chromosome–positive acute lymphoblastic leukemia (Ph+ALL) treated with imatinib
resolves10.1182/blood.V104.11.2738.2738
Update of the Hyper-CVAD and Imatinib Mesylate Regimen in Philadelphia (Ph) Positive Acute Lymphocytic Leukemia (ALL).
resolves10.1182/blood-2004-04-1389
Combination of intensive chemotherapy and imatinib can rapidly induce high-quality complete remission for a majority of patients with newly diagnosed BCR-ABL-positive acute lymphoblastic leukemia
resolves10.1182/blood.V104.11.4483.4483
Treatment of Philadelphia Chromosome (Ph)-Positive Acute Lymphoblastic Leukemia (ALL) with Concurrent Chemotherapy and Imatinib Mesylate.
resolves10.1182/blood.V104.11.685.685
Imatinib Given Concurrently with Induction Chemotherapy Is Superior to Imatinib Subsequent to Induction and Consolidation in Newly Diagnosed Philadelphia-Positive Acute Lymphoblastic Leukemia (PH+ALL).
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Dramatic Improvement in CR Rate and CR Duration with Imatinib in Adult and Elderly Ph+ ALL Patients: Results of the GIMEMA Prospective Study LAL0201.
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Imatinib Combined with Intensive HAM Chemotherapy as Consolidation of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph1-ALL). Preliminary Results of the AFR03 Phase I/II Study.
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Treatment of Philadelphia-Positive Acute Lymphocytic Leukemia (Ph+ ALL) in the Elderly with Imatinib Mesylate (STI571) and Chemotherapy. an Interim Analysis of the GRAALL AFR09 Trial.
resolves10.1182/blood-2004-09-3785
The effect of first-line imatinib interim therapy on the outcome of allogeneic stem cell transplantation in adults with newly diagnosed Philadelphia chromosome–positive acute lymphoblastic leukemia
resolves10.1080/10428190310001625755
Mechanisms of Resistance to STI571 (Imatinib) in Philadelphia-chromosome Positive Acute Lymphoblastic Leukemia
resolves10.1038/sj.leu.2402889
Resistance of Philadelphia-chromosome positive leukemia towards the kinase inhibitor imatinib (STI571, Glivec): a targeted oncoprotein strikes back
resolves10.1182/blood-2002-06-1756
Presence of the BCR-ABL mutation Glu255Lys prior to STI571 (imatinib) treatment in patients with Ph+ acute lymphoblastic leukemia
resolves10.1182/blood.V89.7.2602
Detection of bcr-abl Transcripts in Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia After Marrow Transplantation
resolves10.1038/sj.leu.2402729
Efficacy of imatinib mesylate (STI571) in conjunction with alpha-interferon: long-term quantitative molecular remission in relapsed P-190BCR-ABL-positive acute lymphoblastic leukemia
resolves10.1038/sj.leu.2403093
Efficacy and safety of imatinib mesylate (Glivec™) in combination with interferon-α (IFN-α) in Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL)
resolves10.1016/S0889-8588(05)70204-5
Salvage Therapy for Refractory or Relapsed Acute Lymphocytic Leukemia
resolves10.1038/sj.leu.2402770
Therapy with imatinib mesylate (Glivec) preceding allogeneic stem cell transplantation (SCT) in relapsed or refractory Philadelphia-positive acute lymphoblastic leukemia (Ph+ALL)
resolves10.1016/j.ccr.2005.01.007
Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl
resolves10.1126/science.1099480
Overriding Imatinib Resistance with a Novel ABL Kinase Inhibitor
resolves10.1182/blood.V104.11.22.22
A Phase I/II Study of AMN107, a Novel Aminopyrimidine Inhibitor of Bcr-Abl, on a Continuous Daily Dosing Schedule in Adult Patients (pts) with Imatinib-Resistant Advanced Phase Chronic Myeloid Leukemia (CML) or Relapsed/Refractory Philadelphia Chromosome (Ph+) Acute Llymphocytic Leukemia (ALL).
resolves10.1182/blood.V104.11.20.20
Hematologic and Cytogenetic Responses in Imatinib-Resistant Accelerated and Blast Phase Chronic Myeloid Leukemia (CML) Patients Treated with the Dual SRC/ABL Kinase Inhibitor BMS-354825: Results from a Phase I Dose Escalation Study.
resolves10.1182/blood.V100.3.1068
Overcoming STI571 resistance with the farnesyl transferase inhibitor SCH66336
resolves10.1038/sj.onc.1205724
Phosphatidylinositol-3 kinase inhibitors enhance the anti-leukemia effect of STI571
The 7 references without a DOI — listed, not checked
no DOI — not checkedNowell PC, Hungerford D. A minute chromosome in human chronic granulocytic leukemias. Science. 1960;14:97.
no DOI — not checkedHoelzer D, Gökbuget N. Treatment of elderly patients with acute lymphoblastic leukemia. ASCO Education Book, 41st Annual Meeting May 13–17, 2005:533–539.
no DOI — not checkedMartin TG, Gajewski JL. Allogeneic stem cell transplantation for acute lymphocytic leukemia in adults. Advances in the treatment of adult acute lymphocytic leukemia, Hematol/ Oncol Clin North Am. 2001;15:97–120.
no DOI — not checkedMartin H, Atta J, Klein SA, et al. Autologous BMT/PBSCT in 40 patients with bcr-abl positive acute lymphoblastic leukemia: long-term follow-up of a GMALL study [abstract]. Hematology. 2001;I:187.
no DOI — not checkedOttmann OG, Wassmann B, Gökbuget N, et al. A randomized phase II study comparing Imatinib with chemotherapy as induction therapy in elderly patients with newly diagnosed Philadelphia-positive acute lymphoid leukemias (Ph+ALL) [abstract]. Hematology J. 2004;5:S112.
no DOI — not checkedPfeifer H, Wassmann B, Hofmann WK, et al. Risk and prognosis of central nervous system (CNS) leukemia in patients with Philadelphia chromosome positive (Ph+) acute leukemias treated with imatinib mesylate (GlivecTM). Clin Cancer Res. 2003;9:4674–4681.
no DOI — not checkedWassmann B, Pfeifer H, Stadler M, et al. Early molecular response to post-transplant imatinib determines outcome in MRD-positive Philadelphia-positive acute lymphoblastic leukemia (Ph+ALL). Blood First Edition Paper, prepublished online April 7, 2005; Blood-2004-05-1746.
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