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Transporters in human platelets: physiologic function and impact for pharmacotherapy
94/94 checkable references clean · checked 2026-07-23
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
6 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 94 checked references that resolve
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Platelet factor 4 binds to bacteria, inducing antibodies cross-reacting with the major antigen in heparin-induced thrombocytopenia
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Megakaryocyte dense granule components are sorted in multivesicular bodies
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Platelet and Megakaryocyte Dense Granules Contain Glycoproteins Ib and IIb-IIIa
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Albinism Associated with Hemorrhagic Diathesis and Unusual Pigmented Reticular Cells in the Bone Marrow: Report of Two Cases with Histochemical Studies
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The nucleotide transporter MRP4 (ABCC4) is highly expressed in human platelets and present in dense granules, indicating a role in mediator storage
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Transmembrane Transport of Endo- and Xenobiotics by Mammalian ATP-Binding Cassette Multidrug Resistance Proteins
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Multidrug resistance protein 4 (MRP4/ABCC4): a versatile efflux transporter for drugs and signalling molecules
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Aspirin Extrusion From Human Platelets Through Multidrug Resistance Protein-4–Mediated Transport
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ATP-Dependent Transport of Leukotrienes B4 and C4 by the Multidrug Resistance Protein ABCC4 (MRP4)
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Release of sphingosine‐1‐phosphate from human platelets is dependent on thromboxane formation
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The influence of selective serotonin reuptake inhibitors on human platelet serotonin
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Role of serotonin in the pathophysiology of depression: focus on the serotonin transporter
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GABA and glutamate transporters are expressed in human platelets
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Human Platelets Express Organic Anion-Transporting Peptide 2B1, an Uptake Transporter for Atorvastatin
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The ABCA subfamily—gene and protein structures, functions and associated hereditary diseases
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The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs
resolves10.1038/sj.tpj.6500451
Variability in human hepatic MRP4 expression: influence of cholestasis and genotype
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Inherited Platelet δ-Storage Pool Disease in Dogs Causing Severe Bleeding: An Animal Model for a Specific ADP Deficiency
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Overexpression of the Multidrug Resistance Protein-4 Transporter in Patients Undergoing Coronary Artery Bypass Graft Surgery
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The Identification of a Distinct Export Step following the Biosynthesis of Leukotriene C4 by Human Eosinophils
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The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.
resolves10.1038/nm1197-1275
Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein
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Characterization of the Transport Properties of Cloned Rat Multidrug Resistance-associated Protein 3 (MRP3)
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Demonstration of leukotriene‐C<sub>4</sub> synthase in platelets and species distribution of the enzyme activity
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PROSTANOID TRANSPORT BY MULTIDRUG RESISTANCE PROTEIN 4 (MRP4/ABCC4) LOCALIZED IN TISSUES OF THE HUMAN UROGENITAL TRACT
resolves10.1074/jbc.M104833200
Transport of Cyclic Nucleotides and Estradiol 17-β-d-Glucuronide by Multidrug Resistance Protein 4
resolves10.1007/s10555-007-9039-1
Physiological and pharmacological functions of Mrp2, Mrp3 and Mrp4 as determined from recent studies on gene-disrupted mice
resolves10.1016/S0022-2275(20)32448-2
Characterization of a leukotriene C4 export mechanism in human platelets: possible involvement of multidrug resistance-associated protein 1
resolves10.1053/jhep.2003.50331
Cotransport of Reduced Glutathione With Bile Salts by Mrp4 (Abcc4) Localized to the Basolateral Hepatocyte Membrane
resolves10.1042/bj3140433
ATP-dependent glutathione disulphide transport mediated by the <i>MRP</i> gene-encoded conjugate export pump
resolves10.1016/S0006-291X(03)00659-4
Cloning of rat ABCA7 and its preferential expression in platelets
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Platelet microparticles and vascular cells interactions: A checkpoint between the haemostatic and thrombotic responses
resolves10.1016/j.bbalip.2003.07.003
Scott syndrome, a bleeding disorder caused by defective scrambling of membrane phospholipids
resolves10.1038/11914
The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease
resolves10.1038/11921
Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1
resolves10.1038/35017029
ABC1 promotes engulfment of apoptotic cells and transbilayer redistribution of phosphatidylserine.
resolves10.1182/blood-2004-05-2056
A novel missense mutation in ABCA1 results in altered protein trafficking and reduced phosphatidylserine translocation in a patient with Scott syndrome
resolves10.5551/jat.6726
Roles of ATP-Binding Cassette Transporter A7 in Cholesterol Homeostasis and Host Defense System
resolves10.1038/ng.803
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
resolves10.1007/s00424-006-0062-9
Function and pathophysiological importance of ABCB4 (MDR3 P-glycoprotein)
resolves10.1073/pnas.96.12.6931
Lysophosphatidic acid mediates the rapid activation of platelets and endothelial cells by mildly oxidized low density lipoprotein and accumulates in human atherosclerotic lesions
resolves10.1161/ATVBAHA.107.151837
Individual Heterogeneity in Platelet Response to Lysophosphatidic Acid
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5‐HT
<sub>2A</sub>
Receptor Activation and Nitric Oxide Synthesis: A Possible Mechanism Determining Migraine Attacks
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Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization.
resolves10.1111/j.1471-4159.1993.tb03522.x
Primary Structure of the Human Platelet Serotonin Uptake Site: Identity with the Brain Serotonin Transporter
resolves10.1007/s00424-003-1064-5
Synaptic uptake and beyond: the sodium- and chloride-dependent neurotransmitter transporter family SLC6
resolves10.1016/0005-2728(93)90109-S
From synapse to vesicle: The reuptake and storage of biogenic amine neurotransmitters
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Effects of selective serotonin reuptake inhibitors on platelet serotonin parameters in major depressive disorder
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The effect of citalopram treatment on platelet serotonin function in panic disorders
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Serotonin reuptake inhibitors and cardiovascular diseases: a platelet connection
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Genetic variation in the serotonin transporter promoter region affects serotonin uptake in human blood platelets
resolves10.1016/j.ahj.2005.03.062
Influence of serotonin transporter gene polymorphism on depressive symptoms and new cardiac events after acute myocardial infarction
resolves10.1161/CIRCGENETICS.109.870386
Serotonin Transporter Gene, Depressive Symptoms, and Interleukin-6
resolves10.1124/mol.53.4.649
Altered Brain Serotonin Homeostasis and Locomotor Insensitivity to 3,4-Methylenedioxymethamphetamine (“Ecstasy”) in Serotonin Transporter-Deficient Mic
resolves10.1073/pnas.89.22.10993
Expression cloning of a reserpine-sensitive vesicular monoamine transporter.
resolves10.1073/pnas.93.10.5166
Distinct pharmacological properties and distribution in neurons and endocrine cells of two isoforms of the human vesicular monoamine transporter.
resolves10.1073/pnas.92.19.8773
The vesicular monoamine transporter 2 is present in small synaptic vesicles and preferentially localizes to large dense core vesicles in rat solitary tract nuclei.
resolves10.1016/j.freeradbiomed.2006.11.028
Translational control of the ascorbic acid transporter SVCT2 in human platelets
resolves10.1182/blood-2006-08-040196
The Slc35d3 gene, encoding an orphan nucleotide sugar transporter, regulates platelet-dense granules
resolves10.1007/s00424-003-1093-0
Molecular physiology and pathology of the nucleotide sugar transporter family (SLC35)
resolves10.1016/S0735-1097(99)00525-2
The evolving role of statins in the management of atherosclerosis
resolves10.1161/hc0902.104713
Homocysteine Induces 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase in Vascular Endothelial Cells
resolves10.1096/fj.05-5067fje
Atorvastatin desensitizes β‐adrenergic signaling in cardiac myocytes via reduced isoprenylation of G‐protein γ‐subunits
resolves10.1097/01.fpc.0000114750.08559.32
High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1)
resolves10.1016/j.clpt.2006.09.010
Organic anion transporting polypeptide 2B1 is a high-affinity transporter for atorvastatin and is expressed in the human heart
resolves10.1053/j.gastro.2006.02.034
Drug and Bile Acid Transporters in Rosuvastatin Hepatic Uptake: Function, Expression, and Pharmacogenetics
resolves10.1038/ni.2140
A platelet-mediated system for shuttling blood-borne bacteria to CD8α+ dendritic cells depends on glycoprotein GPIb and complement C3
The 6 references without a DOI — listed, not checked
no DOI — not checkedAnatomy and structural organization of the platelet.
no DOI — not checkedMolecular mechanisms of platelet exocytosis: insights into the “secrete” life of thrombocytes.
no DOI — not checkedWesche J Jehmlich U Schwertz H Expression of the choline transporter like protein 2 (CTL2) in platelets. Hämostaseologie 2011 Accessed September 16, 2011 A78 www.haemostaseologie-online.com
no DOI — not checkedBiological effects of lysophospholipids.
no DOI — not checkedTissue distribution of the human MDR3 P-glycoprotein.
no DOI — not checkedInfluence of dehydroepiandrosterone on platelet aggregation, superoxide dismutase activity and serum lipid peroxide concentrations in rabbits with induced hypercholesterolemia.
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