Reference health

Recurrent adenylation domain replacement in the microcystin synthetase gene cluster

https://doi.org/10.1186/1471-2148-7-183
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33/33 checkable references clean · checked 2026-07-23

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

4 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 33 checked references that resolve
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Insertional mutagenesis of a peptide synthetase gene that is responsible for hepatotoxin production in the cyanobacterium <i>Microcystis aeruginosa</i> PCC 7806
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Genetic Analysis of the Peptide Synthetase Genes for a Cyclic Heptapeptide Microcystin in Microcystis spp.
resolves10.1093/oxfordjournals.jbchem.a022670
Polyketide Synthase Gene Coupled to the Peptide Synthetase Module Involved in the Biosynthesis of the Cyclic Heptapeptide Microcystin
resolves10.1016/S1074-5521(00)00021-1
Structural organization of microcystin biosynthesis in Microcystis aeruginosa PCC7806: an integrated peptide–polyketide synthetase system
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Microcystin Biosynthesis in <i>Planktothrix</i> : Genes, Evolution, and Manipulation
resolves10.1128/AEM.70.2.686-692.2004
Genes Coding for Hepatotoxic Heptapeptides (Microcystins) in the Cyanobacterium <i>Anabaena</i> Strain 90
resolves10.1073/pnas.0304489101
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Abundance of active and inactive microcystin genotypes in populations of the toxic cyanobacterium <i>Planktothrix</i> spp.
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Modular Peptide Synthetases Involved in Nonribosomal Peptide Synthesis
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Molecular Mechanisms Underlying Nonribosomal Peptide Synthesis:  Approaches to New Antibiotics
resolves10.1099/mic.0.26837-0
Substrate recognition by nonribosomal peptide synthetase multi-enzymes
resolves10.1126/science.7604280
Rational Design of Peptide Antibiotics by Targeted Replacement of Bacterial and Fungal Domains
resolves10.1016/S1074-5521(99)80082-9
The specificity-conferring code of adenylation domains in nonribosomal peptide synthetases
resolves10.1073/pnas.100075897
Construction of hybrid peptide synthetases by module and domain fusions
resolves10.1128/JB.185.9.2774-2785.2003
Natural Variation in the Microcystin Synthetase Operon <i>mcyABC</i> and Impact on Microcystin Production in <i>Microcystis</i> Strains
resolves10.1007/s00239-004-2583-1
Evidence for Recombination in the Microcystin Synthetase (mcy) Genes ofToxic Cyanobacteria Microcystis spp
resolves10.1099/mic.0.27779-0
Genetic identification of microcystin ecotypes in toxic cyanobacteria of the genus Planktothrix
resolves10.1186/1471-2148-7-78
Phylogenetic analysis of condensation domains in NRPS sheds light on their functional evolution
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Diversity of Microcystin Genes within a Population of the Toxic Cyanobacterium Microcystis spp. in Lake Wannsee (Berlin, Germany)
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Recombination in the Genesis and Evolution of Hepatitis B Virus Genotypes
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Possible Emergence of New Geminiviruses by Frequent Recombination
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A Modified Bootscan Algorithm for Automated Identification of Recombinant Sequences and Recombination Breakpoints
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Sister-Scanning: a Monte Carlo procedure for assessing signals in recombinant sequences
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Specificity prediction of adenylation domains in nonribosomal peptide synthetases (NRPS) using transductive support vector machines (TSVMs)
The 4 references without a DOI — listed, not checked
no DOI — not checkedSivonen K, Jones G: Cyanobacterial toxins. Toxic cyanobacteria in water. Edited by: Chorus I, Bartram J. 1999, London, E&FN Spon, 41-111.
no DOI — not checkedFelsenstein J: Phylogeny Inference Package (PHYLIP). Version 3.5. 1993, University of Washington, Seattle
no DOI — not checkedMaynard Smith J: Analyzing the mosaic structure of genes. J Mol Evol. 1992, 34: 126-129.
no DOI — not checkedSwofford DL: PAUP*. Phylogenetic Analysis Using Parsimony (*and Other Methods). Version 4. 1998, Massachusetts: Sinauer Associates, Sunderland
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