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A behavioral test battery for mouse models of Angelman syndrome: a powerful tool for testing drugs and novel Ube3a mutants

https://doi.org/10.1186/s13229-018-0231-7
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53/53 checkable references clean · checked 2026-07-23

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

5 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 53 checked references that resolve
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Clinical, cytogenetic, and molecular diagnosis of Angelman syndrome: Estimated prevalence rate in a Danish county
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A Neurodevelopmental Survey of Angelman Syndrome With Genotype-Phenotype Correlations
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Mutation of the Angelman Ubiquitin Ligase in Mice Causes Increased Cytoplasmic p53 and Deficits of Contextual Learning and Long-Term Potentiation
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Behavioral deficits in an Angelman syndrome model: Effects of genetic background and age
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Strain-dependence of the Angelman Syndrome phenotypes in Ube3a maternal deficiency mice
resolves10.1186/1471-2156-12-7
Normal social seeking behavior, hypoactivity and reduced exploratory range in a mouse model of Angelman syndrome
resolves10.1371/journal.pone.0012278
Altered Ultrasonic Vocalization and Impaired Learning and Memory in Angelman Syndrome Mouse Model with a Large Maternal Deletion from Ube3a to Gabrb3
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Neurobehavioral and Electroencephalographic Abnormalities in Ube3aMaternal-Deficient Mice
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Levodopa responsive Parkinsonism in adults with Angelman Syndrome
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resolves10.1038/nn1845
Rescue of neurological deficits in a mouse model for Angelman syndrome by reduction of αCaMKII inhibitory phosphorylation
resolves10.1523/JNEUROSCI.23-07-02634.2003
Derangements of Hippocampal Calcium/Calmodulin-Dependent Protein Kinase II in a Mouse Model for Angelman Mental Retardation Syndrome
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An open-label pilot trial of minocycline in children as a treatment for Angelman syndrome
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A randomized controlled trial of levodopa in patients with Angelman syndrome
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A randomized placebo controlled clinical trial to evaluate the efficacy and safety of minocycline in patients with Angelman syndrome (A-MANECE study)
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Minocycline promotes dendritic spine maturation and improves behavioural performance in the fragile X mouse model
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resolves10.1111/j.1460-9568.2005.04182.x
Minocycline blocks bilirubin neurotoxicity and prevents hyperbilirubinemia‐induced cerebellar hypoplasia in the Gunn rat
resolves10.1016/j.brainres.2009.09.017
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resolves10.1016/j.jneumeth.2014.06.012
Marble burying as a test of the delayed anxiogenic effects of acute immobilisation stress in mice
resolves10.3791/50978
Marble Burying and Nestlet Shredding as Tests of Repetitive, Compulsive-like Behaviors in Mice
resolves10.1016/j.jneumeth.2014.02.001
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resolves10.3791/3638
The Mouse Forced Swim Test
resolves10.1371/journal.pgen.1004039
Truncation of Ube3a-ATS Unsilences Paternal Ube3a and Ameliorates Behavioral Defects in the Angelman Syndrome Mouse Model
resolves10.1186/1824-7288-36-31
Epilepsy in patients with Angelman syndrome
resolves10.1177/0883073809338626
Levetiracetam in Nonconvulsive Status Epilepticus in a Child With Angelman Syndrome
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Minocycline treatment reverses ultrasonic vocalization production deficit in a mouse model of Fragile X Syndrome
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Adeno-Associated Virus-Mediated Rescue of the Cognitive Defects in a Mouse Model for Angelman Syndrome
resolves10.1111/ejn.12893
Reelin supplementation recovers synaptic plasticity and cognitive deficits in a mouse model for Angelman syndrome
resolves10.1016/j.nbd.2012.04.002
Ampakines promote spine actin polymerization, long-term potentiation, and learning in a mouse model of Angelman syndrome
resolves10.1016/j.celrep.2015.06.023
UBE3A Regulates Synaptic Plasticity and Learning and Memory by Controlling SK2 Channel Endocytosis
resolves10.1007/s00018-016-2269-z
mTORC1–S6K1 inhibition or mTORC2 activation improves hippocampal synaptic plasticity and learning in Angelman syndrome mice
resolves10.1038/srep02116
Location- and sex-specific differences in weight and motor coordination in two commonly used mouse strains
resolves10.1037/0735-7044.116.4.600
Behavioral differences among 129 substrains: Implications for knockout and transgenic mice.
resolves10.1034/j.1601-183X.2003.00028.x
Differences among eight inbred strains of mice in motor ability and motor learning on a rotorod
resolves10.1002/ajmg.a.33179
A novel <i>UBE3A</i> truncating mutation in large Tunisian Angelman syndrome pedigree
resolves10.1371/journal.pbio.1001609
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Behavioral effects of ventilated micro-environment housing in three inbred mouse strains
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resolves10.1152/physiolgenomics.90207.2008
Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory study
The 5 references without a DOI — listed, not checked
no DOI — not checkedSilva-santos S, Van Woerden GM, Bruinsma CF, Mientjes E, Jolfaei MA, Distel B, et al. Ube3a reinstatement identifies distinct developmental windows in a murine Angelman syndrome model. J Clin Invest. 2015;125Silva-s:1–8.
no DOI — not checkedWang T, van Woerden GM, Elgersma Y, Borst JGG. Enhanced transmission at the calyx of Held synapse in a mouse model for Angelman syndrome. Front Cell Neurosci. 2018;11:1–19.
no DOI — not checkedGrieco J. Minocycline treatment and the necessity to develop a novel outcome measure for children with Angelman syndrome. Grad Theses Diss. 2015; http://scholarcommons.usf.edu/etd/5693 .
no DOI — not checkedVan Zutphen LFM, Baumans V, Beynen AC. Principles of laboratory animal science: a contribution to the humane use and care of animals and to the quality of experimental results. Amsterdam: Elsevier B.V.; 2001.
no DOI — not checkedPelc K, Cheron G, Dan B. Behavior and neuropsychiatric manifestations in Angelman syndrome. Neuropsychiatric Dis Treat. 2008;4(3):577–84.
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