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Loss of Human Epidermal Growth Factor Receptor 2 (HER2) Expression in Metastatic Sites of HER2-Overexpressing Primary Breast Tumors

https://doi.org/10.1200/jco.2010.33.8889
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31/31 checkable references clean · checked 2026-07-23

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

7 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 31 checked references that resolve
resolves10.1002/(SICI)1096-9098(200001)73:1<17::AID-JSO5>3.0.CO;2-2
c-erbB-2 protein overexpression and p53 immunoreaction in primary and recurrent breast cancer tissues
resolves10.1093/jnci/93.15.1141
Patterns of HER-2/neu Amplification and Overexpression in Primary and Metastatic Breast Cancer
resolves10.1056/NEJM200103153441101
Use of Chemotherapy plus a Monoclonal Antibody against HER2 for Metastatic Breast Cancer That Overexpresses HER2
resolves10.1038/modpathol.3880503
Amplification of Her-2/neu Gene in Her-2/neu-Overexpressing and -Nonexpressing Breast Carcinomas and Their Synchronous Benign, Premalignant, and Metastatic Lesions Detected by FISH in Archival Material
resolves10.1093/annonc/mdf252
Comparison of HER-2 status between primary breast cancer and corresponding distant metastatic sites
resolves10.1023/B:BREA.0000004378.15859.51
Influence of Neoadjuvant Therapy with Epirubicin and Docetaxel on the Expression of HER2/neu in Patients with Breast Cancer
resolves10.1002/path.1592
Change of HER‐2/neu status in a subset of distant metastases from breast carcinomas
resolves10.1038/sj.bjc.6601881
HER2 expression in breast cancer primary tumours and corresponding metastases. Original data and literature review
resolves10.1038/sj.bjc.6602738
Comparison of HER-2 overexpression in primary breast cancer and metastatic sites and its effect on biological targeting therapy of metastatic disease
resolves10.1002/cncr.20987
Comparison of <i>HER‐2</i> status determined by fluorescence in situ hybridization in primary and metastatic breast carcinoma
resolves10.1007/s10549-006-9300-2
Correlation between genetic and biological aspects in primary non-metastatic breast cancers and corresponding synchronous axillary lymph node metastasis
resolves10.1093/annonc/mdp028
Does confirmatory tumor biopsy alter the management of breast cancer patients with distant metastases?
resolves10.1007/s10549-008-9931-6
HER-2/neu expression in primary and metastatic breast cancer
resolves10.1007/s10549-010-1029-2
HER2 status in a population-derived breast cancer cohort: discordances during tumor progression
resolves10.1186/bcr2771
Prospective comparison of switches in biomarker status between primary and recurrent breast cancer: the Breast Recurrence In Tissues Study (BRITS)
resolves10.1200/JCO.2003.03.124
Preoperative Therapy With Trastuzumab and Paclitaxel Followed by Sequential Adjuvant Doxorubicin/Cyclophosphamide for HER2 Overexpressing Stage II or III Breast Cancer: A Pilot Study
resolves10.1200/JCO.2005.02.8886
Docetaxel, Cisplatin, and Trastuzumab As Primary Systemic Therapy for Human Epidermal Growth Factor Receptor 2–Positive Locally Advanced Breast Cancer
resolves10.1158/1078-0432.CCR-06-1304
Predictors of Resistance to Preoperative Trastuzumab and Vinorelbine for HER2-Positive Early Breast Cancer
resolves10.1158/1078-0432.CCR-09-1735
Loss of <i>HER2</i> Amplification Following Trastuzumab-Based Neoadjuvant Systemic Therapy and Survival Outcomes
resolves10.1002/cncr.10456
HER2 status in patients with breast carcinoma is not modified selectively by preoperative chemotherapy and is stable during the metastatic process
resolves10.1016/S0039-6109(03)00034-3
Staging system for breast cancer: revisions for the 6th edition of the AJCC Cancer Staging Manual
resolves10.1038/nature08989
Genome remodelling in a basal-like breast cancer metastasis and xenograft
resolves10.1002/ijc.2910630113
Clonal heterogeneity in breast cancer: Karyotypic comparisons of multiple intra—and extra—tumorous samples from 3 patients
resolves10.4161/cc.6.19.4914
Breast Tumor Heterogeneity: Cancer Stem Cells or Clonal Evolution?
resolves10.1093/annonc/mdp263
Prognostic impact of discordance between triple-receptor measurements in primary and recurrent breast cancer
resolves10.1634/theoncologist.2010-0059
Estrogen and HER-2 Receptor Discordance Between Primary Breast Cancer and Metastasis
resolves10.1007/s10549-004-6275-8
Determination of HER2 Gene Amplification by Fluorescence In situ Hybridization and Concordance with the Clinical Trials Immunohistochemical Assay in Women with Metastatic Breast Cancer Evaluated for Treatment with Trastuzumab
resolves10.1200/JCO.2005.03.4744
<i>HER2</i> Testing by Local, Central, and Reference Laboratories in Specimens From the North Central Cancer Treatment Group N9831 Intergroup Adjuvant Trial
resolves10.1158/1078-0432.CCR-05-0636
Diagnostic Evaluation of HER-2 as a Molecular Target: An Assessment of Accuracy and Reproducibility of Laboratory Testing in Large, Prospective, Randomized Clinical Trials
resolves10.1200/JCO.2007.14.8197
Guidelines for Human Epidermal Growth Factor Receptor 2 Testing: Biologic and Methodologic Considerations
resolves10.1093/jnci/94.11.852
Real-World Performance of HER2 Testing--National Surgical Adjuvant Breast and Bowel Project Experience
The 7 references without a DOI — listed, not checked
no DOI — not checkedB1
no DOI — not checkedB4
no DOI — not checkedB13
no DOI — not checkedB25
no DOI — not checkedB26
no DOI — not checkedB28
no DOI — not checkedB37
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