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Development of a Novel Bilosomal System for Improved Oral Bioavailability of Sertraline Hydrochloride: Formulation Design, In Vitro Characterization, and Ex Vivo and In Vivo Studies
54/54 checkable references clean · checked 2026-07-22
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
11 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 54 checked references that resolve
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Sertraline-Cyclodextrin Complex Orodispersible Sublingual Tablet: Optimization, Stability, and Pharmacokinetics
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Formulation optimization and in vitro characterization of sertraline loaded self-nanoemulsifying drug delivery system (SNEDDS) for oral administration
resolves10.1208/s12249-016-0586-z
Preparation and Optimization of Sertraline Hydrochloride Tablets with Improved Dissolution Through Crystal Modification
resolves10.7324/JAPS.2015.50410
Development of Enteric Coated Sustained Release Matrix Tablets of Sertraline Hydrochloride
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Systematic Development of Sertraline Loaded Solid Lipid Nanoparticle (SLN) by Emulsification-Ultrasonication Method and Pharmacokinetic Study in Sprague-Dawley Rats
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Nanocarriers: A General Strategy for Enhancement of Oral Bioavailability of Poorly Absorbed or Pre-Systemically Metabolized Drugs
resolves10.1016/j.jsps.2021.02.003
Bioactive Apigenin loaded oral nano bilosomes: Formulation optimization to preclinical assessment
resolves10.1016/j.jddst.2020.101634
Bilosomes nanocarriers for improved oral bioavailability of acyclovir: A complete characterization through in vitro, ex-vivo and in vivo assessment
resolves10.1080/03639045.2017.1361968
Improved hepatoprotective activity of silymarin via encapsulation in the novel vesicular nanosystem bilosomes
resolves10.2147/IJN.S37984
Development of a novel niosomal system for oral delivery of Ginkgo biloba extract
resolves10.1208/s12249-018-1019-y
Transdermal Delivery of Ondansetron Hydrochloride via Bilosomal Systems: In Vitro, Ex Vivo, and In Vivo Characterization Studies
resolves10.1016/j.ijpharm.2015.07.041
Cellular uptake, cytotoxicity and in-vivo evaluation of Tamoxifen citrate loaded niosomes
resolves10.1016/j.ejps.2016.09.002
Development and in-vitro characterization of sorbitan monolaurate and poloxamer 184 based niosomes for oral delivery of diacerein
resolves10.3109/03639045.2013.845841
Potentials of proniosomes for improving the oral bioavailability of poorly water-soluble drugs
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Wet agglomeration by high shear of binary mixtures of curcumin-loaded lyophilized liposomes and cornstarch: Powder characterization and incorporation in cakes
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Encapsulation of food waste compounds in soy phosphatidylcholine liposomes: Effect of freeze-drying, storage stability and functional aptitude
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Drug Loading into and In Vitro Release from Nanosized Drug Delivery Systems
resolves10.1155/2014/959741
Formulation and Characterization of Drug Loaded Nonionic Surfactant Vesicles (Niosomes) for Oral Bioavailability Enhancement
resolves10.1208/s12249-016-0481-7
Glycosylated Sertraline-Loaded Liposomes for Brain Targeting: QbD Study of Formulation Variabilities and Brain Transport
resolves10.1016/j.jddst.2017.07.020
Lipid nanocarriers for tamoxifen citrate/coenzyme Q10 dual delivery
resolves10.1371/journal.pone.0219752
Design of bile-based vesicles (BBVs) for hepatocytes specific delivery of Daclatasvir: Comparison of ex-vivo transenterocytic transport, in-vitro protein adsorption resistance and HepG2 cellular uptake of charged and β-sitosterol decorated vesicles
resolves10.1016/j.ijpharm.2014.11.001
Lipid based nanocarrier system for the potential oral delivery of decitabine: Formulation design, characterization, ex vivo, and in vivo assessment
resolves10.36468/pharmaceutical-sciences.708
Characterization and Ex vivo Studies of Nanoparticle Incorporated Transdermal Patch of Itraconazole
resolves10.1002/jssc.201200586
Determination of sertraline in rat plasma by <scp>HPLC</scp> and fluorescence detection and its application to <i>in vivo</i> pharmacokinetic studies
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A simple practice guide for dose conversion between animals and human
resolves10.1093/chrsci/49.2.89
Development and Validation of an Improved Method for the Quantitation of Sertraline in Human Plasma using LC-MS-MS and Its Application to Bioequivalence Studies
resolves10.1016/j.jchromb.2005.09.035
Rapid and sensitive method for the determination of sertraline in human plasma using liquid chromatography–tandem mass spectrometry (LC–MS/MS)
resolves10.1016/j.jfda.2016.08.003
Physicochemical analysis and nonisothermal kinetic study of sertraline–lactose binary mixtures
resolves10.1016/j.ijpharm.2015.03.033
Investigating the potential of employing bilosomes as a novel vesicular carrier for transdermal delivery of tenoxicam
resolves10.1081/DDC-100107675
A Nifedipine Coground Mixture with Sodium Deoxycholate. I. Colloidal Particle Formation and Solid-State Analysis
resolves10.1016/j.ijpharm.2017.05.029
Sertaconazole nitrate loaded nanovesicular systems for targeting skin fungal infection: In-vitro, ex-vivo and in-vivo evaluation
resolves10.4314/tjpr.v17i8.1
Development of niosomal formulations loaded with cyclosporine A and evaluation of its compatibility
resolves10.3390/pharmaceutics13050638
Piceatannol-Loaded Bilosome-Stabilized Zein Protein Exhibits Enhanced Cytostatic and Apoptotic Activities in Lung Cancer Cells
resolves10.1016/j.ejpb.2004.03.037
Once-daily propranolol extended-release tablet dosage form: formulation design and in vitro/in vivo investigation
resolves10.1208/s12249-007-9018-4
Optimization Studies on Design and Evaluation of Orodispersible Pediatric Formulation of Indomethacin
resolves10.1042/BSR20090104
Celecoxib-loaded liposomes: effect of cholesterol on encapsulation and <i>in vitro</i> release characteristics
resolves10.3389/fphar.2018.01283
Bile Acids and Their Derivatives as Potential Modifiers of Drug Release and Pharmacokinetic Profiles
resolves10.3797/scipharm.1208-02
Transfersomes: A Novel Vesicular Carrier for Enhanced Transdermal Delivery of Sertraline: Development, Characterization, and Performance Evaluation
resolves10.1016/j.ijpharm.2009.04.022
Enhanced bioavailability of the poorly water-soluble drug fenofibrate by using liposomes containing a bile salt
resolves10.1007/s13346-020-00715-6
Methylene blue-loaded niosome: preparation, physicochemical characterization, and in vivo wound healing assessment
resolves10.1007/s40204-021-00164-5
Evaluation of sonication on stability-indicating properties of optimized pilocarpine hydrochloride-loaded niosomes in ocular drug delivery
resolves10.1016/j.jelechem.2005.12.001
How non-ionic “electrically neutral” surfactants enhance electrical conductivity and ion stability in non-polar liquids
resolves10.3390/pharmaceutics12121132
Solid Lipid Nanoparticles as Formulative Strategy to Increase Oral Permeation of a Molecule Active in Multidrug-Resistant Tuberculosis Management
resolves10.1080/10611860801927598
Pharmacokinetics and targeting property of TFu-loaded liposomes with different sizes after intravenous and oral administration
resolves10.1208/pt0804106
Influence of a niosomal formulation on the oral bioavailability of acyclovir in rabbits
resolves10.3109/08982104.2016.1158185
A lyophilized sterically stabilized liposome-containing docetaxel: <i>in vitro</i> and <i>in vivo</i> evaluation
resolves10.1016/j.ejps.2019.04.013
Impact of regional differences along the gastrointestinal tract of healthy adults on oral drug absorption: An UNGAP review
The 11 references without a DOI — listed, not checked
no DOI — not checkedSingh HK, Saadabadi A. Sertraline. StatPearls. Treasure Island (FL): StatPearls Publishing; 2021. http://www.ncbi.nlm.nih.gov/pubmed/31613469
no DOI — not checkedArzani G, Haeri A, Daeihamed M, Bakhtiari-Kaboutaraki H, Dadashzadeh S. Niosomal carriers enhance oral bioavailability of carvedilol: effects of bile salt-enriched vesicles and carrier surface charge. Int J Nanomedicine. 2015 Jul;10:4797–813.
no DOI — not checkedRajput T, Chauhan MK. Bilosome: a bile salt based novel carrier system gaining interest in pharmaceutical research. J Drug Deliv Ther. 2017 Sep 15;7(5):4–16.
no DOI — not checkedRudra A, Deepa RM, Ghosh MK, Ghosh S, Mukherjee B. Doxorubicin-loaded phosphatidylethanolamine-conjugated nanoliposomes: in vitro characterization and their accumulation in liver, kidneys, and lungs in rats. Int J Nanomedicine. 2010;5(1):811–23.
no DOI — not checkedDai Y, Zhou R, Liu L, Lu Y, Qi J, Wu W. Liposomes containing bile salts as novel ocular delivery systems for tacrolimus (FK506): in vitro characterization and improved corneal permeation. Int J Nanomedicine. 2013;8:1921–33.
no DOI — not checkedDash S, Murthy PN, Nath L, Chowdhury P. Kinetic modeling on drug release from controlled drug delivery systems. Acta Pol Pharm. 2010;67(3):217–23.
no DOI — not checkedElsayed I, Abdelbary AA, Elshafeey AH. Nanosizing of a poorly soluble drug: technique optimization, factorial analysis, and pharmacokinetic study in healthy human volunteers. Int J Nanomedicine. 2014;9(1):2943–53.
no DOI — not checkedBright A, Renuga Devi TS, Gunasekaran S. Qualitative and quantitative analysis of antipsychotic drugs-a spectroscopic study. Asian J Chem. 2010;22(8):5871–82.
no DOI — not checkedAburahma MH. Bile salts-containing vesicles: promising pharmaceutical carriers for oral delivery of poorly water-soluble drugs and peptide/protein-based therapeutics or vaccines. Drug Deliv. 2016;23(6):1847–67.
no DOI — not checkedEmami J, Mohiti H, Hamishehkar H, Varshosaz J. Formulation and optimization of solid lipid nanoparticle formulation for pulmonary delivery of budesonide using Taguchi and Box-Behnken design. Res Pharm Sci. 2015;10(1):17–33. Available from: https://pubmed.ncbi.nlm.nih.gov/26430454
no DOI — not checkedShokri M, Tavallaie M, Hosseini SM. Effect of lyophilization on the size and polydispersity of unilamellar and multilamellar liposomes. J Nanotechnol Mater Sci. 2016;3(2):1–4.
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