Reference health

Epitope spreading as an early pathogenic event in pediatric multiple sclerosis

https://doi.org/10.1212/wnl.0000000000001066
CiteStamped reference-health badge
28/28 checkable references clean · checked 2026-07-23

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

The 28 checked references that resolve
resolves10.1016/S1474-4422(07)70242-9
Multiple sclerosis in children: clinical diagnosis, therapeutic strategies, and future directions
resolves10.1038/nrneurol.2009.158
Pediatric multiple sclerosis
resolves10.1016/S1474-4422(11)70250-2
MRI parameters for prediction of multiple sclerosis diagnosis in children with acute CNS demyelination: a prospective national cohort study
resolves10.1073/pnas.0404848101
Functional immunomics: Microarray analysis of IgG autoantibody repertoires predicts the future response of mice to induced diabetes
resolves10.1038/nm0302-295
Autoantigen microarrays for multiplex characterization of autoantibody responses
resolves10.1001/archneur.64.10.nct70002
Induction of Antigen-Specific Tolerance in Multiple Sclerosis After Immunization With DNA Encoding Myelin Basic Protein in a Randomized, Placebo-Controlled Phase 1/2 Trial
resolves10.1002/ana.21370
Phase 2 trial of a DNA vaccine encoding myelin basic protein for multiple sclerosis
resolves10.1038/nm1344
Lipid microarrays identify key mediators of autoimmune brain inflammation
resolves10.1212/WNL.0b013e318247f9f3
Antigen microarrays identify CNS-produced autoantibodies in RRMS
resolves10.1073/pnas.0806310105
Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis
resolves10.1038/nature06880
Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor
resolves10.1038/nbt859
Protein microarrays guide tolerizing DNA vaccine treatment of autoimmune encephalomyelitis
resolves10.1016/S1474-4422(11)70045-X
Clinical, environmental, and genetic determinants of multiple sclerosis in children with acute demyelination: a prospective national cohort study
resolves10.1002/ana.20703
Diagnostic criteria for multiple sclerosis: 2005 revisions to the “McDonald Criteria”
resolves10.1016/S1474-4422(09)70275-3
Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: a weighted genetic risk score
resolves10.1212/WNL.0b013e318228c0b1
Antibodies to MOG are transient in childhood acute disseminated encephalomyelitis
resolves10.1038/358155a0
Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen
resolves10.1038/nri724
Epitope spreading in immune-mediated diseases: implications for immunotherapy
resolves10.1093/brain/123.3.508
Repertoire dynamics of autoreactive T cells in multiple sclerosis patients and healthy subjects: Epitope spreading versus clonal persistence
resolves10.1038/ni1430
CNS myeloid DCs presenting endogenous myelin peptides 'preferentially' polarize CD4+ TH-17 cells in relapsing EAE
resolves10.1038/nm1202
Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis
resolves10.1172/JCI29251
Alterations in CD46-mediated Tr1 regulatory T cells in patients with multiple sclerosis
resolves10.1212/WNL.0b013e3182a2ce0e
T-cell homeostasis in pediatric multiple sclerosis
resolves10.1084/jem.20031579
Loss of Functional Suppression by CD4+CD25+ Regulatory T Cells in Patients with Multiple Sclerosis
resolves10.1002/jnr.20852
Secondary progressive in contrast to relapsing‐remitting multiple sclerosis patients show a normal CD4<sup>+</sup>CD25<sup>+</sup> regulatory T‐cell function and FOXP3 expression
resolves10.1002/ana.22693
Implication of perturbed axoglial apparatus in early pediatric multiple sclerosis
resolves10.1073/pnas.1009201107
An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis
resolves10.1073/pnas.1120611109
Nanoparticle-mediated codelivery of myelin antigen and a tolerogenic small molecule suppresses experimental autoimmune encephalomyelitis
What this badge says. CiteStamped means the CHECKABLE references of this work were clean at the dated check: each resolved to a known work in a public registry, and none carried a retraction notice at that time. It says nothing about the quality, findings, or importance of the work itself, and nothing about references deposited without a DOI.

checked 2026-07-23 — re-checked daily as this page is visited; titles and statuses come from Crossref and DataCite and are not part of the signed record

Embed this badge

Both snippets point at the live badge image and link back to this page. The badge re-renders from the daily check, so an embed never goes stale by more than a day of visits.

<a href="https://citestamp.com/citestamped/10.1212/wnl.0000000000001066"><img src="https://citestamp.com/citestamped/10.1212/wnl.0000000000001066/badge.svg" alt="CiteStamped reference-health badge" width="460" height="64"></a>
[![CiteStamped reference-health badge](https://citestamp.com/citestamped/10.1212/wnl.0000000000001066/badge.svg)](https://citestamp.com/citestamped/10.1212/wnl.0000000000001066)