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Oxidative Inactivation of Mitochondrial Aconitase Results in Iron and H2O2-Mediated Neurotoxicity in Rat Primary Mesencephalic Cultures

https://doi.org/10.1371/journal.pone.0007095
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Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

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The 43 checked references that resolve
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Alpha-ketoglutarate dehydrogenase: a target and generator of oxidative stress
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The inactivation of Fe-S cluster containing hydro-lyases by superoxide.
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Superoxide sensitivity of the Escherichia coli aconitase.
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Superoxide accelerates DNA damage by elevating free-iron levels
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Mitochondrial Aconitase Is a Source of Hydroxyl Radical
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The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen
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Increased Peroxidation and Reduced Antioxidant Enzyme Activity in Alzheimer's Disease
resolves10.1007/BF01291884
Alterations in the distribution of glutathione in the substantia nigra in Parkinson's disease
resolves10.1111/j.1471-4159.2004.02567.x
Iron‐sulfur enzyme mediated mitochondrial superoxide toxicity in experimental Parkinson's disease
resolves10.1016/S0896-6273(00)80052-5
Requirement for Superoxide in Excitotoxic Cell Death
resolves10.1073/pnas.96.3.846
Mitochondrial disease in superoxide dismutase 2 mutant mice
resolves10.1002/jnr.10062
Mitochondrial impairment in the cerebellum of the patients with progressive supranuclear palsy
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Biochemical abnormalities and excitotoxicity in Huntington's disease brain
resolves10.1006/abbi.1999.1158
Mitochondrial Superoxide Decreases Yeast Survival in Stationary Phase
resolves10.1016/0891-5849(94)90239-9
The role of O2.− in the production of HO.: in vitro and in vivo
resolves10.1042/bst0210367
Free radicals and mitochondrial dysfunction in Parkinson's disease
resolves10.1016/S0005-2728(98)00114-5
Mitochondrial dysfunction in neurodegenerative diseases
resolves10.1016/j.arr.2004.01.003
Does cellular iron dysregulation play a causative role in Parkinson’s disease?
resolves10.1074/jbc.M700827200
Mitochondria Are a Major Source of Paraquat-induced Reactive Oxygen Species Production in the Brain
resolves10.1016/j.brainres.2005.03.038
Angiotensin II protects cultured midbrain dopaminergic neurons against rotenone-induced cell death
resolves10.1042/bj3620137
Selective determination of mitochondrial chelatable iron in viable cells with a new fluorescent sensor
resolves10.1046/j.1471-4159.2001.00457.x
Dependence of excitotoxic neurodegeneration on mitochondrial aconitase inactivation
resolves10.1111/j.1528-1167.2007.01280.x
Subfield‐specific Loss of Hippocampal N‐acetyl Aspartate in Temporal Lobe Epilepsy
resolves10.1016/j.eplepsyres.2004.05.003
Inhibition of aconitase in astrocytes increases the sensitivity to chemical convulsants
resolves10.1523/JNEUROSCI.21-13-04582.2001
Neuroprotection from Delayed Postischemic Administration of a Metalloporphyrin Catalytic Antioxidant
resolves10.1046/j.1471-4159.2000.0751977.x
Reversible Inactivation of Superoxide‐Sensitive Aconitase in Aβ1‐42‐Treated Neuronal Cell Lines
resolves10.1073/pnas.0703219104
DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase
resolves10.1016/j.freeradbiomed.2003.11.029
Mitochondrial oxidative stress and increased seizure susceptibility in Sod2−/+ mice
resolves10.1016/S0306-4522(02)00979-X
Age dependence of seizure-induced oxidative stress
resolves10.1073/pnas.94.21.11168
Oxidative damage during aging targets mitochondrial aconitase
resolves10.1002/ana.410360305
Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia
resolves10.1016/0304-3940(92)90355-B
Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's disease
resolves10.1016/S0140-6736(87)91361-4
INCREASED NIGRAL IRON CONTENT IN POSTMORTEM PARKINSONIAN BRAIN
resolves10.1074/jbc.M000120200
Glutathione Depletion in PC12 Results in Selective Inhibition of Mitochondrial Complex I Activity
resolves10.1016/S0896-6273(03)00568-3
Parkinson's Disease
resolves10.1016/j.parkreldis.2004.10.013
Neuroinflammatory processes in Parkinson's disease
The 2 references without a DOI — listed, not checked
no DOI — not checkedChelation of mitochondrial iron prevents seizure-induced mitochondrial dysfunction and neuronal injury.
no DOI — not checkedInactivation of aconitase in yeast exposed to oxidative stress.
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