Reference health
Hepatitis B virus PreS2-mutant large surface antigen activates store-operated calcium entry and promotes chromosome instability
55/55 checkable references clean · checked 2026-07-23
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
3 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 55 checked references that resolve
resolves10.1002/1097-0142(19880515)61:10<1942::AID-CNCR2820611003>3.0.CO;2-J
Hepatitis B virus.The major etiology of hepatocellular carcinoma
resolves10.1016/S0168-8278(86)80024-1
Diverse virological, histopathological and prognostic implications of seroconversion from hepatitis B e antigen to anti-HBe in chronic hepatitis B virus infection
resolves10.1111/j.1440-1746.2008.05348.x
Ground glass hepatocytes contain pre‐S mutants and represent preneoplastic lesions in chronic hepatitis B virus infection
resolves10.1053/jhep.2001.21163
Prevalence and Significance of Hepatitis B Virus (Hbv) Pre–S Mutants in Serum and Liver At Different Replicative Stages of Chronic Hbv Infection
resolves10.1053/j.gastro.2006.01.011
High Prevalence and Mapping of Pre-S Deletion in Hepatitis B Virus Carriers With Progressive Liver Diseases
resolves10.1016/S0002-9440(10)63599-7
Different Types of Ground Glass Hepatocytes in Chronic Hepatitis B Virus Infection Contain Specific Pre-S Mutants that May Induce Endoplasmic Reticulum Stress
resolves10.1099/vir.0.2008/002824-0
Hepatitis B virus pre-S deletion mutations are a risk factor for hepatocellular carcinoma: a matched nested case–control study
resolves10.1203/PDR.0b013e3181c1b0b7
Pre-S2 Deletions of Hepatitis B Virus and Hepatocellular Carcinoma in Children
resolves10.1111/j.1349-7006.2009.01309.x
Pre‐S2 deletion mutants of hepatitis B virus could have an important role in hepatocarcinogenesis in Asian children
resolves10.1046/j.1440-1746.2000.02187.x
Identification of a pre‐S2 mutant in hepatocytes expressing a novel marginal pattern of surface antigen in advanced diseases of chronic hepatitis B virus infection
resolves10.1002/hep.20615
Hepatitis B virus pre‐S2 mutant upregulates cyclin A expression and induces nodular proliferation of hepatocytes†
resolves10.1111/j.1349-7006.2006.00235.x
Hepatitis B virus pre‐S mutants, endoplasmic reticulum stress and hepatocarcinogenesis
resolves10.1093/carcin/bgr296
Aberrant cyclin A expression and centrosome overduplication induced by hepatitis B virus Pre-S2 mutants and its implication in hepatocarcinogenesis
resolves10.1186/s12929-014-0098-7
The emerging role of hepatitis B virus Pre-S2 deletion mutant proteins in HBV tumorigenesis
resolves10.1158/1541-7786.MCR-07-0098
Hepatitis B Virus Pre-S2 Mutant Surface Antigen Induces Degradation of Cyclin-Dependent Kinase Inhibitor p27Kip1 through c-Jun Activation Domain-Binding Protein 1
resolves10.1002/path.4531
Hepatitis B virus pre‐<scp>S<sub>2</sub></scp> mutant large surface protein inhibits <scp>DNA</scp> double‐strand break repair and leads to genome instability in hepatocarcinogenesis
resolves10.1053/j.gastro.2011.12.039
Integrative Genomic Identification of Genes on 8p Associated With Hepatocellular Carcinoma Progression and Patient Survival
resolves10.1111/j.1582-4934.2011.01395.x
<b>Orais and STIMs: physiological mechanisms and disease</b>
resolves10.1126/science.1128294
Chemical Chaperones Reduce ER Stress and Restore Glucose Homeostasis in a Mouse Model of Type 2 Diabetes
resolves10.1074/jbc.M111.274332
Inhibition of Endoplasmic Reticulum-associated Degradation Rescues Native Folding in Loss of Function Protein Misfolding Diseases
resolves10.1074/jbc.M403568200
Endoplasmic Reticulum Stress Stimulates the Expression of Cyclooxygenase-2 through Activation of NF-κB and pp38 Mitogen-activated Protein Kinase
resolves10.1093/carcin/bgh207
Pre-S mutant surface antigens in chronic hepatitis B virus infection induce oxidative stress and DNA damage
resolves10.1002/hep.22889
Enhanced expression of vascular endothelial growth factor‐A in ground glass hepatocytes and its implication in hepatitis B virus hepatocarcinogenesis†
resolves10.1038/sj.onc.1210638
Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis
resolves10.1096/fj.12-218875
Modulation of ER stress and apoptosis by endoplasmic reticulum calcium leak
<i>via</i>
translocon during unfolded protein response: involvement of GRP78
resolves10.1113/jphysiol.2013.255661
The coupling of plasma membrane calcium entry to calcium uptake by endoplasmic reticulum and mitochondria
resolves10.1016/j.cell.2009.02.014
STIM1 Clusters and Activates CRAC Channels via Direct Binding of a Cytosolic Domain to Orai1
resolves10.1038/nature07065
Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation
resolves10.1016/j.jhep.2014.04.041
Hepatitis B virus PreS/S gene variants: Pathobiology and clinical implications
resolves10.1371/journal.pone.0028977
Induction of Bcl-2 Expression by Hepatitis B Virus Pre-S2 Mutant Large Surface Protein Resistance to 5-Fluorouracil Treatment in Huh-7 Cells
resolves10.1093/emboj/21.4.525
The PreS2 activator MHBst of hepatitis B virus activates c‐raf‐1/Erk2 signaling in transgenic mice
resolves10.1007/978-3-642-46870-4_23
The PreS2 Activators of the Hepatitis B Virus: Activators of Tumour Promoter Pathways
resolves10.1002/hep.24529
Novel feedback inhibition of surface antigen synthesis by mammalian target of rapamycin (mTOR) signal and its implication for hepatitis B virus tumorigenesis and therapy
resolves10.1053/gast.1996.v110.pm8536855
Allelic loss on chromosomes 4q and 16q in hepatocellular carcinoma: Association with elevated alpha-fetoprotein production
resolves10.1016/j.prp.2013.04.004
Etiologic influence on chromosomal aberrations in European hepatocellular carcinoma identified by CGH
resolves10.1111/jgh.12010
Risk stratification for hepatitis <scp>B</scp> virus related hepatocellular carcinoma
resolves10.1053/j.gastro.2007.09.002
Pre-S Deletion and Complex Mutations of Hepatitis B Virus Related to Advanced Liver Disease in HBeAg-Negative Patients
resolves10.1073/pnas.1204668109
Hepatitis B virus X protein targets Bcl-2 proteins to increase intracellular calcium, required for virus replication and cell death induction
resolves10.1126/science.294.5550.2376
Calcium Signaling by HBx Protein in Hepatitis B Virus DNA Replication
resolves10.1002/hep.510270428
Expression of hepatitis B virus X protein in HBV-infected human livers and hepatocellular carcinomas
resolves10.1016/j.humpath.2013.10.039
Ground-glass hepatocytes co-expressing hepatitis B virus X protein and surface antigens exhibit enhanced oncogenic effects and tumorigenesis
resolves10.1016/j.canlet.2012.11.040
Blockade of store-operated Ca2+ entry inhibits hepatocarcinoma cell migration and invasion by regulating focal adhesion turnover
resolves10.1073/pnas.1103315108
Calcium store sensor stromal-interaction molecule 1-dependent signaling plays an important role in cervical cancer growth, migration, and angiogenesis
The 3 references without a DOI — listed, not checked
no DOI — not checkedType II ground-glass hepatocytes as a marker of hepatocellular carcinoma in chronic hepatitis B
no DOI — not checkedCytoplasmic hepatitis B antigen in “ground-glass” hepatocytes of carriers
no DOI — not checkedEndoplasmic-reticulum calcium depletion and disease
What this badge says. CiteStamped means the CHECKABLE references of this
work were clean at the dated check: each resolved to a known work in a public registry, and none
carried a retraction notice at that time. It says nothing about the quality, findings,
or importance of the work itself, and nothing about references deposited without a DOI.
checked 2026-07-23 — re-checked daily as this page is visited; titles and statuses come from Crossref and DataCite and are not part of the signed record
Embed this badge
Both snippets point at the live badge image and link back to this page. The badge re-renders from the daily check, so an embed never goes stale by more than a day of visits.
<a href="https://citestamp.com/citestamped/10.18632/oncotarget.8109"><img src="https://citestamp.com/citestamped/10.18632/oncotarget.8109/badge.svg" alt="CiteStamped reference-health badge" width="460" height="64"></a>
[](https://citestamp.com/citestamped/10.18632/oncotarget.8109)