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TMPRSS2 and ADAM17 Cleave ACE2 Differentially and Only Proteolysis by TMPRSS2 Augments Entry Driven by the Severe Acute Respiratory Syndrome Coronavirus Spike Protein
Effect of Mycobacterium tuberculosis Enhancement of Macrophage P-Glycoprotein Expression and Activity on Intracellular Survival During Antituberculosis Drug Treatment
The role of SARS‐CoV‐2 target ACE2 in cardiovascular diseases
The 16 references without a DOI — listed, not checked
no DOI — not checkedHuman Type I IFN neutralizing antibody mix (39000-1) was obtained from PBL Assay Science. Anti-ACE2 antibody (10108-T56 and T60) and anti
no DOI — not checkedCulture of Human induced pluripotent stem cell-derived cardiomyocytes Human iPSC-CMs were plated using the supplier protocol. Briefly, hiPSC-CMs were plated as a monolayer in sterile 12 well cell culture plates coated with 0.1% gelatin and incubated at 37�C and 5% CO 2 in a humidified atmosphere for 48h. Then cells were transferred into CDI maintenance medium for further culture and the maintenance medium was changed every alternate day. For, gelatin coating, 1ml of 0.1% gelatin was added into each well of a 12 well plate and incubated at 37�C for a minimum of 1h. Human iPSC-CMs functional assay with Multi-electrode array system (MEA) After 5-7 days of hiPSC-CMs culturing in the 12 well cell culture plate, the cells were replated onto MEA plate. For this, the sterile 24 well CytoView MEA culture plate (Cat#M384-tMEA-24W
no DOI — not checkedref3
no DOI — not checkedSequential infection with H1N1 and SARS-CoV-2 aggravated COVID-19 pathogenesis in a mammalian model, and co-vaccination as an effective method of prevention of COVID-19 and influenza
no DOI — not checkedAngiotensin converting enzyme 2 is a novel target of the ?-secretase complex
no DOI — not checkedHost Immune Response to Influenza A Virus Infection
no DOI — not checkedSARS-CoV-2 and influenza virus co-infection
no DOI — not checkedref14
no DOI — not checkedDual nature of human ACE2 glycosylation in binding to SARS-CoV-2 spike
no DOI — not checkedInterferons and viruses induce a novel truncated ACE2 isoform and not the full-length SARS-CoV-2 receptor
no DOI — not checkedref36
no DOI — not checkedref37
no DOI — not checkedOpposing activities of IFITM proteins in SARS-CoV-2 infection
no DOI — not checkedFigure Legends: C57BL/6 mice were infected with IAV-PR68 (1x10 4 PFU) and on day 6 the mice were euthanized to harvest the lungs. The lung sections were stained with anti-ACE2 and macrophage marker F4/80 antibodies, followed by AF594 and AF488 conjugated secondary antibodies respectively. The nuclei were stained with DAPI
no DOI — not checkedref47
no DOI — not checkedData analysis was performed using the cardiac analysis tool. (A) Activity map showing changes in beat rate of cardiomyocytes treated with HK SARS-CoV-2. Shown is a representative well from quadruplicate samples for each treatment (N=2). The graphs shown in B is the number of cardiomyocyte beats per minute at baseline and at 12, 18 and 24h post treatment. Data shown is a representative of two independent experiments performed in quadruplicate wells
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