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Long Non-Coding RNA PCAT-NE1 Activates Autophagy via miR-6889-3p-Regulated VPS13A to Induce Neuroendocrine Differentiation

https://doi.org/10.2139/ssrn.3960261
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28/28 checkable references clean · checked 2026-09-01

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

20 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 28 checked references that resolve
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Clinical and Genomic Characterization of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer: A Multi-institutional Prospective Study
resolves10.1158/1078-0432.CCR-19-1423
The Role of Lineage Plasticity in Prostate Cancer Therapy Resistance
resolves10.1038/nm.4045
Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer
resolves10.1172/JCI127961
N-Myc–mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer
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HOTAIR is a REST-regulated lncRNA that promotes neuroendocrine differentiation in castration resistant prostate cancer
resolves10.2217/epi.16.6
The Role of Epigenetics and Long Noncoding RNA MIAT in Neuroendocrine Prostate Cancer
resolves10.1038/onc.2016.135
Neuroendocrine prostate cancer (NEPCa) increased the neighboring PCa chemoresistance via altering the PTHrP/p38/Hsp27/androgen receptor (AR)/p21 signals
resolves10.1038/s41467-020-19328-1
Role of specialized composition of SWI/SNF complexes in prostate cancer lineage plasticity
resolves10.1016/j.ccell.2016.09.005
N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer
resolves10.1530/ERC-19-0420
The epigenetic and transcriptional landscape of neuroendocrine prostate cancer
resolves10.1038/nrurol.2018.22
Cellular plasticity and the neuroendocrine phenotype in prostate cancer
resolves10.4161/auto.19226
Interleukin-6
resolves10.1101/gr.132159.111
The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression
resolves10.1038/nrg3606
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19q13.11 cryptic deletion: description of two new cases and indication for a role of WTIP haploinsufficiency in hypospadias
resolves10.1016/j.annonc.2020.02.002
Epigenetic modulations and lineage plasticity in advanced prostate cancer
resolves10.1038/labinvest.2014.165
The potential of neurotensin secreted from neuroendocrine tumor cells to promote gelsolin-mediated invasiveness of prostate adenocarcinoma cells
resolves10.1097/00000658-194206000-00030
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resolves10.1126/science.aah4199
<i>Rb1</i> and <i>Trp53</i> cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance
resolves10.1002/path.4047
From sequence to molecular pathology, and a mechanism driving the neuroendocrine phenotype in prostate cancer
resolves10.1093/annonc/mdt136
Antitumour activity of abiraterone acetate against metastatic castration-resistant prostate cancer progressing after docetaxel and enzalutamide (MDV3100)
resolves10.1126/science.aah4307
<i>SOX2</i> promotes lineage plasticity and antiandrogen resistance in <i>TP53</i> - and <i>RB1</i> -deficient prostate cancer
resolves10.1038/nbt.1914
Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression
resolves10.1038/nm.4341
Biology and evolution of poorly differentiated neuroendocrine tumors
resolves10.1093/nar/gkt921
REST mediates androgen receptor actions on gene repression and predicts early recurrence of prostate cancer
resolves10.1038/nrc4016
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The 20 references without a DOI — listed, not checked
no DOI — not checkedBRN4 Is a Novel Driver of Neuroendocrine Differentiation in Castration-Resistant Prostate Cancer and Is Selectively Released in Extracellular Vesicles with BRN2
no DOI — not checkedAutophagy pathway is required for IL-6 induced neuroendocrine differentiation and chemoresistance of prostate cancer LNCaP cells
no DOI — not checkedREST is a crucial regulator for acquiring EMTlike and stemness phenotypes in hormone-refractory prostate cancer
no DOI — not checkedVps13 is required for the packaging of the ER into autophagosomes during ER-phagy
no DOI — not checkedNeuroendocrine prostate cancer: long noncoding RNAs to treat an incurable cancer -an interview with Dr Francesco Crea
no DOI — not checkedAbiraterone and increased survival in metastatic prostate cancer
no DOI — not checkedDD3(PCA3), a very sensitive and specific marker to detect prostate tumors
no DOI — not checkedInterplay between long noncoding RNAs and epigenetic machinery: emerging targets in cancer?
no DOI — not checkedN-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells
no DOI — not checkedREST reduction is essential for hypoxia-induced neuroendocrine differentiation of prostate cancer cells by activating autophagy signaling
no DOI — not checkedLong non-coding RNAs in lung cancer: implications for lineage plasticity-mediated TKI resistance
no DOI — not checkedLncRNA-p21 alters the antiandrogen enzalutamide-induced prostate cancer neuroendocrine differentiation via modulating the EZH2/STAT3 signaling
no DOI — not checkedChromatin crosstalk in development and disease: lessons from REST
no DOI — not checkedref39
no DOI — not checkedref40
no DOI — not checkedProstate cancer: Hand in hand -Rb1 and Trp53 cooperate to suppress resistance
no DOI — not checkedLong noncoding RNA as modular scaffold of histone modification complexes
no DOI — not checkedNONCODEv4: exploring the world of long non-coding RNA genes
no DOI — not checkedref47
no DOI — not checkedref48
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