Reference health
Chronic Exposure to Environmentally Relevant Concentrations of Guanylurea Impairs the Behavior, Redox Status, Acetylcholinesterase Homeostasis, And Expression of Antioxidant Defense-, Apoptosis-, and Neuronal Communication-Related Genes Of Danio Rerio Adults
39/39 checkable references clean · checked 2026-07-23
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
22 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 39 checked references that resolve
resolves10.1007/s13402-018-0398-0
Metformin inhibits human breast cancer cell growth by promoting apoptosis via a ROS-independent pathway involving mitochondrial dysfunction: pivotal role of superoxide dismutase (SOD)
resolves10.1038/nrd3505
The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics
resolves10.1038/s41598-020-66584-8
Amyloid precursor protein-b facilitates cell adhesion during early development in zebrafish
resolves10.1016/j.etap.2019.103311
Triclosan alters adult zebrafish behavior and targets acetylcholinesterase activity and expression
resolves10.1177/0269881120944155
An acetylcholinesterase inhibitor, donepezil, increases anxiety and cortisol levels in adult zebrafish
resolves10.1016/j.aquatox.2017.09.012
Short-term and persistent impacts on behaviors related to locomotion, anxiety, and startle responses of Japanese medaka (Oryzias latipes) induced by acute, sublethal exposure to chlorpyrifos
resolves10.1038/s41598-019-46804-6
Neurotoxicity of organophosphate pesticides could reduce the ability of fish to escape predation under low doses of exposure
resolves10.1016/j.chemosphere.2014.06.081
AChE inhibition: One dominant factor for swimming behavior changes of Daphnia magna under DDVP exposure
resolves10.3389/fgene.2019.00435
Regulation of Mitochondrial Biogenesis as a Way for Active Longevity: Interaction Between the Nrf2 and PGC-1α Signaling Pathways
resolves10.1007/s11011-014-9632-2
Pre-treatment with metformin activates Nrf2 antioxidant pathways and inhibits inflammatory responses through induction of AMPK after transient global cerebral ischemia
resolves10.1111/febs.13698
<scp>AMP</scp>‐activated protein kinase: a cellular energy sensor that comes in 12 flavours
resolves10.1016/j.jhazmat.2018.12.084
Metformin-induced endocrine disruption and oxidative stress of Oryzias latipes on two-generational condition
resolves10.1038/nprot.2010.140
Measuring behavioral and endocrine responses to novelty stress in adult zebrafish
resolves10.1073/pnas.0807991106
Antidiabetic drug metformin (Glucophage
<sup>R</sup>
) increases biogenesis of Alzheimer's amyloid peptides via up-regulating
<i>BACE1</i>
transcription
resolves10.3233/JAD-141332
Metformin Treatment Alters Memory Function in a Mouse Model of Alzheimer's Disease
resolves10.1371/journal.pone.0182868
Contaminants of emerging concern in tributaries to the Laurentian Great Lakes: I. Patterns of occurrence
resolves10.1016/0006-2952(61)90145-9
A new and rapid colorimetric determination of acetylcholinesterase activity
resolves10.1016/j.chemosphere.2018.03.049
Ketamine induction of p53-dependent apoptosis and oxidative stress in zebrafish (Danio rerio) embryos
resolves10.1093/nar/gkw1043
Spliceosomal protein eftud2 mutation leads to p53-dependent apoptosis in zebrafish neural progenitors
resolves10.1016/S0076-6879(94)33040-9
[37] Carbonyl assays for determination of oxidatively modified proteins
resolves10.1002/cne.23746
Differential expression of <i>protocadherin‐19</i>, <i>protocadherin‐17</i>, and <i>cadherin‐6</i> in adult zebrafish brain
resolves10.1371/journal.pone.0197259
Environmental concentrations of metformin exposure affect aggressive behavior in the Siamese fighting fish, Betta splendens
resolves10.1016/j.ejogrb.2020.11.070
Efficacy of simvastatin plus metformin for polycystic ovary syndrome: A meta-analysis of randomized controlled trials
resolves10.1016/j.bbrc.2004.07.095
Expression of zebrafish glutamate receptor δ2 in neurons with cerebellum-like wiring
resolves10.3233/JAD-2011-110533
The BACE1-PSEN-AβPP Regulatory Axis has an Ancient Role in Response to Low Oxygen/Oxidative Stress
resolves10.1016/j.bbamcr.2015.01.017
Metformin increases APP expression and processing via oxidative stress, mitochondrial dysfunction and NF-κB activation: Use of insulin to attenuate metformin's effect
resolves10.1016/j.redox.2017.05.023
The role of Nrf1 and Nrf2 in the regulation of glutathione and redox dynamics in the developing zebrafish embryo
resolves10.1016/j.watres.2012.06.019
Occurrence and fate of the antidiabetic drug metformin and its metabolite guanylurea in the environment and during drinking water treatment
resolves10.1016/j.scitotenv.2018.02.105
Formation and occurrence of transformation products of metformin in wastewater and surface water
resolves10.1016/j.watres.2018.11.001
Aerobic and anaerobic formation and biodegradation of guanyl urea and other transformation products of metformin
resolves10.1016/j.envint.2014.05.008
Occurrence of the antidiabetic drug Metformin and its ultimate transformation product Guanylurea in several compartments of the aquatic cycle
resolves10.1111/apha.12644
Metformin is not just an antihyperglycaemic drug but also has protective effects on the vascular endothelium
resolves10.1016/j.aquatox.2018.10.003
Effects of environmentally relevant metformin exposure on Japanese medaka (Oryzias latipes)
resolves10.1016/j.jchemneu.2020.101849
The possible role of progranulin on anti-inflammatory effects of metformin in temporal lobe epilepsy
resolves10.3390/molecules24183256
RNA-seq Based Transcriptome Analysis of the Anti-Obesity Effect of Green Tea Extract Using Zebrafish Obesity Models
resolves10.1016/j.lfs.2020.117717
Anticancer mechanisms of metformin: A review of the current evidence
The 22 references without a DOI — listed, not checked
no DOI — not checkedref7
no DOI — not checkedSwimming impairment and acetylcholinesterase inhibition in zebrafish exposed to copper or chlorpyrifos separately, or as mixtures
no DOI — not checkedref12
no DOI — not checkedref15
no DOI — not checkedMetformin Inhibits Lipoteichoic Acid-Induced Oxidative Stress and Inflammation Through AMPK/NRF2/NF-?B Signaling Pathway in Bovine Mammary Epithelial Cells
no DOI — not checkedref18
no DOI — not checkedOccurrence, toxic effects and removal of metformin in the aquatic environments in the world: Recent trends and perspectives
no DOI — not checkedOxidative stress as a potential mechanism by which guanylurea disrupts the embryogenesis of Danio rerio
no DOI — not checkedref29
no DOI — not checkedFerrous ion oxidation in the presence of xylenol orange for detection of lipid hydroperoxide in low density lipoprotein
no DOI — not checkedMetformin alters locomotor and cognitive function and brain metabolism in normoglycemic mice
no DOI — not checkedThe role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase
no DOI — not checkedBiological and biophysics aspects of metformin-induced effects: cortex mitochondrial dysfunction and promotion of toxic amyloid pre-fibrillar aggregates
no DOI — not checkedDetermination of polar organic micropollutants in surface and pore water by high-resolution sampling-direct injection-ultra high performance liquid chromatography-tandem mass spectrometry
no DOI — not checkedDetection of catalase in rat heart mitochondria
no DOI — not checkedref44
no DOI — not checked17 ? -ethynilestradiol and tributyltin mixtures modulates the expression of NER and p53 DNA repair pathways in male zebra fi sh gonads and disrupt o ff spring embryonic development
no DOI — not checkedAn 'omics approach to investigate the growth effects of environmentally relevant concentrations of guanylurea exposure on Japanese medaka (Oryzias latipes)
no DOI — not checkedref54
no DOI — not checkedDevelopmental and full-life cycle exposures to guanylurea, and guanylurea-metformin mixtures results in adverse effects on Japanese medaka (Oryzias latipes)
no DOI — not checkedEffectiveness of rapid cooling as a method of euthanasia for young zebrafish (Danio rerio)
no DOI — not checkedMetformin: a review of its potential indications. Drug design, development and therapy, 11, 2421
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