Reference health
Matrix Stiffness Enhances Cancer-Macrophage Interactions and M2-Like Macrophage Accumulation in the Breast Tumor Microenvironment
60/60 checkable references clean · checked 2026-09-08
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
11 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 60 checked references that resolve
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The Mechanical Rigidity of the Extracellular Matrix Regulates the Structure, Motility, and Proliferation of Glioma Cells
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Matrix stiffness drives epithelial–mesenchymal transition and tumour metastasis through a TWIST1–G3BP2 mechanotransduction pathway
resolves10.1038/oncsis.2017.54
Matrix stiffness induces epithelial–mesenchymal transition and promotes chemoresistance in pancreatic cancer cells
resolves10.1152/ajpcell.00418.2018
Matrix stiffness regulates microvesicle-induced fibroblast activation
resolves10.1038/ncb2756
Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
resolves10.1016/j.actbio.2012.08.007
Tuning three-dimensional collagen matrix stiffness independently of collagen concentration modulates endothelial cell behavior
resolves10.1039/c5ib00040h
Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration
resolves10.1007/s00249-015-1096-8
Substrate elasticity regulates the behavior of human monocyte-derived macrophages
resolves10.1007/s00018-014-1796-8
Physical and mechanical regulation of macrophage phenotype and function
resolves10.1038/nm.3337
CSF-1R inhibition alters macrophage polarization and blocks glioma progression
resolves10.1016/j.ccell.2019.08.007
Tumor Cell Biodiversity Drives Microenvironmental Reprogramming in Liver Cancer
resolves10.1038/s41596-020-0292-x
CellPhoneDB: inferring cell–cell communication from combined expression of multi-subunit ligand–receptor complexes
resolves10.1016/j.xpro.2021.100450
Processing single-cell RNA-seq data for dimension reduction-based analyses using open-source tools
resolves10.1186/s13059-019-1874-1
Normalization and variance stabilization of single-cell RNA-seq data using regularized negative binomial regression
resolves10.1038/nri3088
Transcriptional regulation of macrophage polarization: enabling diversity with identity
resolves10.1038/cdd.2012.146
TLR2-dependent selective autophagy regulates NF-κB lysosomal degradation in hepatoma-derived M2 macrophage differentiation
resolves10.1093/intimm/dxh316
Allograft inflammatory factor-1 (AIF-1) is crucial for the survival and pro-inflammatory activity of macrophages
resolves10.1182/blood-2009-12-258186
The chemokine CXCL12 regulates monocyte-macrophage differentiation and RUNX3 expression
resolves10.4049/jimmunol.0902792
Matricellular Protein CCN1 Activates a Proinflammatory Genetic Program in Murine Macrophages
resolves10.1210/me.2014-1092
Lipocalin 2 is a Regulator Of Macrophage Polarization and NF-κB/STAT3 Pathway Activation
resolves10.1016/j.jid.2016.04.005
EpCAM Expressed by Murine Epidermal Langerhans Cells Modulates Immunization to an Epicutaneously Applied Protein Antigen
resolves10.1038/sj.jid.5701228
CD24a Expression Levels Discriminate Langerhans Cells from Dermal Dendritic Cells in Murine Skin and Lymph Nodes
resolves10.1016/S1471-4906(02)02302-5
Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
resolves10.1161/CIRCRESAHA.117.312509
Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine Atherosclerosis
resolves10.15252/emmm.201404838
The cholesterol‐binding protein NPC2 restrains recruitment of stromal macrophage‐lineage cells to early‐stage lung tumours
resolves10.1007/s12032-014-0884-9
Anti-inflammatory macrophages activate invasion in pancreatic adenocarcinoma by increasing the MMP9 and ADAM8 expression
resolves10.1016/j.yexcr.2017.08.028
Upregulation of PD-L1 by SPP1 mediates macrophage polarization and facilitates immune escape in lung adenocarcinoma
resolves10.1080/15548627.2015.1009787
Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization
resolves10.1016/j.lfs.2021.119800
Transfer of miRNA in tumor-derived exosomes suppresses breast tumor cell invasion and migration by inducing M1 polarization in macrophages
resolves10.1016/j.ccell.2019.01.007
Integrin Signaling in Cancer: Mechanotransduction, Stemness, Epithelial Plasticity, and Therapeutic Resistance
resolves10.1016/j.cell.2009.10.027
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
resolves10.1016/j.cell.2017.10.044
Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer
resolves10.1038/s41467-019-14134-w
Cancer-associated fibroblast heterogeneity in axillary lymph nodes drives metastases in breast cancer through complementary mechanisms
resolves10.4049/jimmunol.1000413
Tumor-Conditioned Macrophages Secrete Migration-Stimulating Factor: A New Marker for M2-Polarization, Influencing Tumor Cell Motility
resolves10.1016/j.jss.2009.05.026
Significance of M2-Polarized Tumor-Associated Macrophage in Pancreatic Cancer
resolves10.1016/j.ejca.2006.01.003
Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: Potential targets of anti-cancer therapy
resolves10.18632/oncotarget.2110
Macrophages are recruited to hypoxic tumor areas and acquire a Pro-Angiogenic M2-Polarized phenotype via hypoxic cancer cell derived cytokines Oncostatin M and Eotaxin
resolves10.1016/j.humpath.2008.08.011
High tumor-infiltrating macrophage density predicts poor prognosis in patients with primary hepatocellular carcinoma after resection
resolves10.1159/000012021
Tumor-Associated Macrophage Infiltration in Pulmonary Adenocarcinoma: Association with Angiogenesis and Poor Prognosis
resolves10.1183/09031936.00065708
Macrophages within NSCLC tumour islets are predominantly of a cytotoxic M1 phenotype associated with extended survival
resolves10.1073/pnas.1406655111
Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment
resolves10.1039/C4IB00260A
Macrophage motility is driven by frontal-towing with a force magnitude dependent on substrate stiffness
resolves10.1002/adhm.201600967
Instructing Human Macrophage Polarization by Stiffness and Glycosaminoglycan Functionalization in 3D Collagen Networks
resolves10.1021/acsbiomaterials.8b00910
Macrophage Polarization in Response to Collagen Scaffold Stiffness Is Dependent on Cross-Linking Agent Used To Modulate the Stiffness
resolves10.1016/j.actbio.2019.02.048
Material stiffness influences the polarization state, function and migration mode of macrophages
resolves10.1016/j.yexcr.2018.04.005
Reduced substrate stiffness promotes M2-like macrophage activation and enhances peroxisome proliferator-activated receptor γ expression
resolves10.1016/j.colsurfa.2018.04.026
The interacting role of physical stiffness and tumor cells on the macrophages polarization
resolves10.1016/j.pbiomolbio.2019.05.006
PCL/EUG scaffolds with tunable stiffness can regulate macrophage secretion behavior
resolves10.1177/153537020422900101
The Role of CSF-1 in Normal Physiology of Mammary Gland and Breast Cancer: An Update
resolves10.1200/JCO.2018.36.15_suppl.3014
Phase Ib/II study of lacnotuzumab (MCS110) combined with spartalizumab (PDR001) in patients (pts) with advanced tumors.
resolves10.1126/scitranslmed.aao0475
Targeting extracellular matrix stiffness to attenuate disease: From molecular mechanisms to clinical trials
resolves10.1189/jlb.0609385
Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation
The 11 references without a DOI — listed, not checked
no DOI — not checkedMatrix Stiffness Regulates Endothelial Cell Proliferation through Septin 9
no DOI — not checkedUnsupervised Trajectory Analysis of Single-Cell RNA-Seq and Imaging Data Reveals Alternative Tuft Cell Origins in the Gut
no DOI — not checkedref21
no DOI — not checkedModulators of the Balance between M1 and M2 Macrophages during Pregnancy
no DOI — not checkedMacrophage Polarization: Different Gene Signatures in M1(LPS+) vs. Classically and M2(LPS-) vs
no DOI — not checkedref46
no DOI — not checkedTumor-recruited M2 macrophages promote gastric and breast cancer metastasis via M2 macrophage-secreted CHI3L1 protein
no DOI — not checkedTissue invasive macrophage density is correlated with prognosis in cholangiocarcinoma
no DOI — not checkedThe M1 form of tumor-associated macrophages in non-small cell lung cancer is positively associated with survival time
no DOI — not checkedA Randomized Phase II Study of Anti-CSF-1 Monoclonal Antibody Lacnotuzumab (MCS110) Combined with Gemcitabine and Carboplatin in Advanced Triple Negative Breast Cancer
no DOI — not checkedTumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium
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