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Tumor-Associated Macrophages Promoting PD-L1 Expression in Regulatory B Cells Through the CXCL12/CXCR4 Axis in Human Hepatocellular Carcinoma

https://doi.org/10.2139/ssrn.4045949
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35/35 checkable references clean · checked 2026-07-23

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

3 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 35 checked references that resolve
resolves10.1016/j.molcel.2020.05.004
Ectosomal PKM2 Promotes HCC by Inducing Macrophage Differentiation and Remodeling the Tumor Microenvironment
resolves10.1053/j.gastro.2013.01.002
Role of the Microenvironment in the Pathogenesis and Treatment of Hepatocellular Carcinoma
resolves10.1007/s12307-012-0111-1
Inflammatory Immune Responses in Tumor Microenvironment and Metastasis of Hepatocellular Carcinoma
resolves10.1038/cmi.2017.35
B cell regulation in cancer and anti-tumor immunity
resolves10.3389/fimmu.2020.582657
Phenotypes, Functions, and Clinical Relevance of Regulatory B Cells in Cancer
resolves10.1016/S1074-7613(02)00274-1
Chronic Intestinal Inflammatory Condition Generates IL-10-Producing Regulatory B Cell Subset Characterized by CD1d Upregulation
resolves10.1038/nature24302
Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity
resolves10.1093/intimm/dxz068
Heterogeneous subsets of B-lineage regulatory cells (Breg cells)
resolves10.1038/nm.3680
Regulatory B cells are induced by gut microbiota–driven interleukin-1β and interleukin-6 production
resolves10.1038/nature11501
Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions
resolves10.1016/j.immuni.2014.06.010
Tumor-Associated Macrophages: From Mechanisms to Therapy
resolves10.1158/1078-0432.CCR-13-0855
PD-L1 Expression Is Characteristic of a Subset of Aggressive B-cell Lymphomas and Virus-Associated Malignancies
resolves10.1080/2162402X.2017.1413520
A novel MDSC-induced PD-1 <sup>−</sup> PD-L1 <sup>+</sup> B-cell subset in breast tumor microenvironment possesses immuno-suppressive properties
resolves10.1016/j.molimm.2020.01.008
PD-L1+ regulatory B cells act as a T cell suppressor in a PD-L1-dependent manner in melanoma patients with bone metastasis
resolves10.1038/s41423-019-0324-z
Dendritic cells license regulatory B cells to produce IL-10 and mediate suppression of antigen-specific CD8 T cells
resolves10.1016/j.immuni.2016.02.012
A Regulatory Feedback between Plasmacytoid Dendritic Cells and Regulatory B Cells Is Aberrant in Systemic Lupus Erythematosus
resolves10.4049/jimmunol.1302593
Mast Cells Control the Expansion and Differentiation of IL-10–Competent B Cells
resolves10.1182/blood-2009-12-258186
The chemokine CXCL12 regulates monocyte-macrophage differentiation and RUNX3 expression
resolves10.1152/ajpcell.00406.2006
Stroma-derived factor (SDF-1/CXCL12) and human tumor pathogenesis
resolves10.1158/1541-7786.MCR-11-0498
New Insight into the SDF-1/CXCR4 Axis in a Breast Carcinoma Model: Hypoxia-Induced Endothelial SDF-1 and Tumor Cell CXCR4 Are Required for Tumor Cell Intravasation
resolves10.1038/onc.2015.139
CXCL12/CXCR4: a symbiotic bridge linking cancer cells and their stromal neighbors in oncogenic communication networks
resolves10.1016/j.cell.2005.02.034
Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion
resolves10.1096/fj.201802067RR
Dual blockade of CXCL12‐CXCR4 and PD‐1–PD‐L1 pathways prolongs survival of ovarian tumor–bearing mice by prevention of immunosuppression in the tumor microenvironment
resolves10.1007/s00428-016-2051-5
CXCL12 expression and PD-L1 expression serve as prognostic biomarkers in HCC and are induced by hypoxia
resolves10.1073/pnas.1320318110
Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti–PD-L1 immunotherapy in pancreatic cancer
resolves10.1002/ijc.31357
IFN‐γ‐mediated inhibition of lung cancer correlates with PD‐L1 expression and is regulated by PI3K‐AKT signaling
resolves10.1007/s10147-017-1161-7
PD-L1 induced by IFN-γ from tumor-associated macrophages via the JAK/STAT3 and PI3K/AKT signaling pathways promoted progression of lung cancer
resolves10.1158/0008-5472.CAN-14-3362
Control of PD-L1 Expression by Oncogenic Activation of the AKT–mTOR Pathway in Non–Small Cell Lung Cancer
resolves10.1158/1078-0432.CCR-11-1942
Constitutive AP-1 Activity and EBV Infection Induce PD-L1 in Hodgkin Lymphomas and Posttransplant Lymphoproliferative Disorders: Implications for Targeted Therapy
resolves10.4049/jimmunol.1003713
Macrophage Migration Inhibitory Factor and CD74 Regulate Macrophage Chemotactic Responses via MAPK and Rho GTPase
resolves10.1186/1465-9921-10-33
Macrophage CD74 contributes to MIF-induced pulmonary inflammation
resolves10.4049/jimmunol.177.11.8072
Macrophage Migration Inhibitory Factor Induces Macrophage Recruitment via CC Chemokine Ligand 2
resolves10.1016/j.cyto.2020.154986
Hypoxia upregulates Cxcl12 in hepatocytes by a complex mechanism involving hypoxia-inducible factors and transforming growth factor-β
resolves10.2147/JIR.S326385
Dysregulation of DPP4-CXCL12 Balance by TGF-β1/SMAD Pathway Promotes CXCR4+ Inflammatory Cell Infiltration in Keloid Scars
resolves10.1038/onc.2016.252
Downregulation of CXCL12 in mesenchymal stromal cells by TGFβ promotes breast cancer metastasis
The 3 references without a DOI — listed, not checked
no DOI — not checkedThe Burden of Primary Liver Cancer and Underlying Etiologies From 1990 to 2015 at the Global, Regional, and National Level: Results From the Global Burden of Disease Study
no DOI — not checkedThe regulatory B cell-mediated peripheral tolerance maintained by mast cell IL-5 suppresses oxazolone-induced contact hypersensitivity
no DOI — not checkedCisplatin contributes to programmed death-ligand 1 expression in bladder cancer through ERK1/2-AP-1 signaling pathway
What this badge says. CiteStamped means the CHECKABLE references of this work were clean at the dated check: each resolved to a known work in a public registry, and none carried a retraction notice at that time. It says nothing about the quality, findings, or importance of the work itself, and nothing about references deposited without a DOI.

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