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Metabolic Reprogramming by Dual-Targeted Biomimetic Nanoparticles for Enhanced Tumor Chemo-Immunotherapy

https://doi.org/10.2139/ssrn.4049688
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28/28 checkable references clean · checked 2026-08-31

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

21 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 28 checked references that resolve
resolves10.18632/oncotarget.18175
The reverse Warburg effect is likely to be an Achilles' heel of cancer that can be exploited for cancer therapy
resolves10.1038/s41591-020-01195-4
Targeting metastatic cancer
resolves10.1038/s41577-019-0140-9
Metabolic interventions in the immune response to cancer
resolves10.1186/1476-4598-12-152
Tumor glycolysis as a target for cancer therapy: progress and prospects
resolves10.1126/science.aaw5473
Metabolic reprogramming and cancer progression
resolves10.1016/j.celrep.2016.04.028
Targeting Metabolic Symbiosis to Overcome Resistance to Anti-angiogenic Therapy
resolves10.1186/1476-4598-9-33
Warburg effect in chemosensitivity: Targeting lactate dehydrogenase-A re-sensitizes Taxol-resistant cancer cells to Taxol
resolves10.1126/science.1160809
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
resolves10.1016/j.semcancer.2014.01.005
Catabolic cancer-associated fibroblasts transfer energy and biomass to anabolic cancer cells, fueling tumor growth
resolves10.1038/nature24057
Glucose feeds the TCA cycle via circulating lactate
resolves10.1016/j.tcb.2017.06.003
Metabolic Interactions in the Tumor Microenvironment
resolves10.1186/s12951-021-01062-5
Ginsenosides emerging as both bifunctional drugs and nanocarriers for enhanced antitumor therapies
resolves10.1186/s12951-020-00649-8
Macrophage-cancer hybrid membrane-coated nanoparticles for targeting lung metastasis in breast cancer therapy
resolves10.1021/acsami.0c13169
Bacterial Vesicle-Cancer Cell Hybrid Membrane-Coated Nanoparticles for Tumor Specific Immune Activation and Photothermal Therapy
resolves10.1002/adma.201602173
Cancer‐Cell‐Biomimetic Nanoparticles for Targeted Therapy of Homotypic Tumors
resolves10.1021/acs.nanolett.6b02786
Preferential Cancer Cell Self-Recognition and Tumor Self-Targeting by Coating Nanoparticles with Homotypic Cancer Cell Membranes
resolves10.1039/D0NR04465B
Fibroblast activation protein-α-adaptive micelles deliver anti-cancer drugs and reprogram stroma fibrosis
resolves10.1016/j.jconrel.2020.02.040
Targeting cancer-associated fibroblasts by dual-responsive lipid-albumin nanoparticles to enhance drug perfusion for pancreatic tumor therapy
resolves10.1021/nl500618u
Cancer Cell Membrane-Coated Nanoparticles for Anticancer Vaccination and Drug Delivery
resolves10.1016/j.ejmech.2020.112612
PFKFB3 inhibitors as potential anticancer agents: Mechanisms of action, current developments, and structure-activity relationships
resolves10.3389/fonc.2020.598626
Lactate Metabolism and Immune Modulation in Breast Cancer: A Focused Review on Triple Negative Breast Tumors
resolves10.1007/978-3-319-77736-8_11
Metabolic Relationship between Cancer-Associated Fibroblasts and Cancer Cells
resolves10.1038/nature13490
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
resolves10.1038/s41586-019-1678-1
Metabolic regulation of gene expression by histone lactylation
resolves10.7150/thno.53749
Lactate-induced M2 polarization of tumor-associated macrophages promotes the invasion of pituitary adenoma by secreting CCL17
resolves10.1016/j.ijrobp.2007.01.041
Macrophages From Irradiated Tumors Express Higher Levels of iNOS, Arginase-I and COX-2, and Promote Tumor Growth
resolves10.1038/s41586-019-1170-y
CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy
resolves10.1038/s41568-019-0238-1
A framework for advancing our understanding of cancer-associated fibroblasts
The 21 references without a DOI — listed, not checked
no DOI — not checkedref6
no DOI — not checkedTurning foes to friends: targeting cancer-associated fibroblasts
no DOI — not checkedref12
no DOI — not checkedMetabolic Symbiosis and Immunomodulation: How Tumor Cell-Derived Lactate May Disturb Innate and Adaptive Immune Responses
no DOI — not checkedref16
no DOI — not checkedFrom Design to Clinic: Engineered Nanobiomaterials for Immune Normalization Therapy of Cancer
no DOI — not checkedNano-delivery systems focused on tumor microenvironment regulation and biomimetic strategies for treatment of breast cancer metastasis
no DOI — not checkedref19
no DOI — not checkedref22
no DOI — not checkedCell Membrane Coated Semiconducting Polymer Nanoparticles for Enhanced Multimodal Cancer Phototheranostics
no DOI — not checkedref27
no DOI — not checkedref29
no DOI — not checkedErythrocyte-Cancer Hybrid Membrane Camouflaged Hollow Copper Sulfide Nanoparticles for Prolonged Circulation Life and Homotypic-Targeting Photothermal/Chemotherapy of Melanoma
no DOI — not checkedBreast Cancer-Associated Fibroblasts: Where We Are and Where We Need to Go
no DOI — not checkedIntra/Extracellular Lactic Acid Exhaustion for Synergistic Metabolic Therapy and Immunotherapy of Tumors
no DOI — not checkedEngineering of Cascade-Responsive Nanoplatform to Inhibit Lactate Efflux for Enhanced Tumor Chemo-Immunotherapy
no DOI — not checkedLactate: A Metabolic Driver in the Tumour Landscape
no DOI — not checkedMetabolic support of tumour-infiltrating regulatory T cells by lactic acid
no DOI — not checkedOptimized biodegradable polymeric reservoir-mediated local and sustained co-delivery of dendritic cells and oncolytic adenovirus co-expressing IL-12 and GM-CSF for cancer immunotherapy
no DOI — not checkedThe immune consequences of lactate in the tumor microenvironment
no DOI — not checkedLactate modulation of immune responses in inflammatory versus tumour microenvironments
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