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A PDK-1 Allosteric Agonist Improves Spatial Learning and Memory in a ΒAPP/PS-1 Transgenic Mouse-High Fat Diet Intervention Model of Alzheimer's Disease
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Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
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The 76 checked references that resolve
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Reversal of high fat diet-induced obesity improves glucose tolerance, inflammatory response, β-amyloid accumulation and cognitive decline in the APP/PSEN1 mouse model of Alzheimer's disease
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<b>Contribution of genetic and dietary insulin resistance to Alzheimer phenotype in APP/PS1 transgenic mice</b>
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A PDK-1 allosteric agonist neutralizes insulin signaling derangements and beta-amyloid toxicity in neuronal cells and in vitro
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Transient intraneuronal Aβ rather than extracellular plaque pathology correlates with neuron loss in the frontal cortex of APP/PS1KI mice
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Intraneuronal Aβ Causes the Onset of Early Alzheimer’s Disease-Related Cognitive Deficits in Transgenic Mice
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β-Amyloid1–42 Gene Transfer Model Exhibits Intraneuronal Amyloid, Gliosis, Tau Phosphorylation, and Neuronal Loss
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1-(3′,4′-Dichloro-2-fluoro[1,1′-biphenyl]-4-yl)-cyclopropanecarboxylic Acid (CHF5074), a Novel γ-Secretase Modulator, Reduces Brain β-Amyloid Pathology in a Transgenic Mouse Model of Alzheimer’s Disease without Causing Peripheral Toxicity
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The γ-Secretase Modulator CHF5074 Restores Memory and Hippocampal Synaptic Plasticity in Plaque-Free Tg2576 Mice
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Memory Impairment in Transgenic Alzheimer Mice Requires Cellular Prion Protein
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Intake of Sucrose-sweetened Water Induces Insulin Resistance and Exacerbates Memory Deficits and Amyloidosis in a Transgenic Mouse Model of Alzheimer Disease
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High-fat diet increases tau expression in the brain of T2DM and AD mice independently of peripheral metabolic status
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Long-Term Memory Is Facilitated by cAMP Response Element-Binding Protein Overexpression in the Amygdala
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Reversible Inhibition of CREB/ATF Transcription Factors in Region CA1 of the Dorsal Hippocampus Disrupts Hippocampus-Dependent Spatial Memory
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Signaling Mechanisms Mediating BDNF Modulation of Memory Formation In Vivo in the Hippocampus
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Role for brain-derived neurotrophic factor in learning and memory
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Enhanced CREB-dependent gene expression increases the excitability of neurons in the basal amygdala and primes the consolidation of contextual and cued fear memory
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Illite improves memory impairment and reduces Aβ level in the Tg-APPswe/PS1dE9 mouse model of Alzheimer׳s disease through Akt/CREB and GSK-3β phosphorylation in the brain
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Pioglitazone Improves Reversal Learning and Exerts Mixed Cerebrovascular Effects in a Mouse Model of Alzheimer’s Disease with Combined Amyloid-β and Cerebrovascular Pathology
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Mitochondria and Synaptic Plasticity in the Mature and Aging Nervous System
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Direct pharmacological Akt activation rescues Alzheimer's disease like memory impairments and aberrant synaptic plasticity
resolves10.1172/JCI59903
Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline
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Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums
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Production of seedable Amyloid-β peptides in model of prion diseases upon PrPSc-induced PDK1 overactivation
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PDK1 decreases TACE-mediated α-secretase activity and promotes disease progression in prion and Alzheimer's diseases
The 14 references without a DOI — listed, not checked
no DOI — not checkedAmyloid precursor protein and proinflammatory changes are regulated in brain and adipose tissue in a murine model of high fat diet-induced obesity
no DOI — not checkedCued and Contextual Fear Conditioning for Rodents
no DOI — not checkedref40
no DOI — not checkedref62
no DOI — not checkedref65
no DOI — not checkedActivation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1DeltaE9 mouse model of Alzheimer's disease
no DOI — not checkedThe incretin hormones glucagonlike peptide 1 and glucose-dependent insulinotropic polypeptide are neuroprotective in mouse models of Alzheimer's disease
no DOI — not checkedref84
no DOI — not checkedref85
no DOI — not checkedref86
no DOI — not checkedref87
no DOI — not checkedref88
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no DOI — not checkedref90
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