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In Vitro Hepatic Metabolism of Polychlorinated Biphenyls with Different Chlorine-Substituted Structures In Rats and Humans: Kinetics, Metabolism, and Potential Nuclear Receptor Affinities
52/52 checkable references clean · checked 2026-07-23
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
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The 52 checked references that resolve
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PLIP 2021: expanding the scope of the protein–ligand interaction profiler to DNA and RNA
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Correction to “Room-to-Room Variability of Airborne Polychlorinated Biphenyls in Schools and the Application of Air Sampling for Targeted Source Evaluation”
resolves10.1021/acs.jctc.8b01176
GFN2-xTB—An Accurate and Broadly Parametrized Self-Consistent Tight-Binding Quantum Chemical Method with Multipole Electrostatics and Density-Dependent Dispersion Contributions
resolves10.1016/j.bcp.2018.07.032
From TCDD-mediated toxicity to searches of physiologic AHR functions
resolves10.1016/S0300-483X(00)00368-1
Effect of highly bioaccumulated polychlorinated biphenyl congeners on estrogen and androgen receptor activity
resolves10.1016/j.envpol.2018.12.041
Non-coplanar and coplanar polychlorinated biphenyls potentiate genotoxicity of aflatoxin B1 in a human hepatocyte line by enhancing CYP1A2 and CYP3A4 expression
resolves10.1021/acs.est.8b04403
Long-Term (1970–2017) Temporal Trends of Polychlorinated Biphenyls in Fish, Settling Material, and Sediments from Populated and Remote Sites in Río de la Plata Estuary, Argentina
resolves10.1016/j.chemosphere.2012.02.074
Field and laboratory studies of the fate and enantiomeric enrichment of venlafaxine and O-desmethylvenlafaxine under aerobic and anaerobic conditions
resolves10.1021/acs.est.8b01540
Human Sex Hormone Disrupting Effects of New Flame Retardants and Their Interactions with Polychlorinated Biphenyls, Polybrominated Diphenyl Ethers, a Case Study in South China
resolves10.1186/1758-2946-4-17
Avogadro: an advanced semantic chemical editor, visualization, and analysis platform
resolves10.1016/j.scitotenv.2020.142590
Comprehensive exploration of the ultraviolet degradation of polychlorinated biphenyls in different media
resolves10.1002/bms.1200010605
Mass spectrometry of the methyl ethers of isomeric hydroxychlorobiphenyls—potential metabolites of chlorobiphenyls
resolves10.1021/es2014727
Gas Chromatographic Analysis with Chiral Cyclodextrin Phases Reveals the Enantioselective Formation of Hydroxylated Polychlorinated Biphenyls by Rat Liver Microsomes
resolves10.1007/s11356-015-4150-2
Chiral polychlorinated biphenyls: absorption, metabolism and excretion—a review
resolves10.1021/ci400649p
Endocrine Disruptome—An Open Source Prediction Tool for Assessing Endocrine Disruption Potential through Nuclear Receptor Binding
resolves10.1021/es402838f
Stereoselective Formation of Mono- and Dihydroxylated Polychlorinated Biphenyls by Rat Cytochrome P450 2B1
resolves10.1021/es200673q
Factors Affecting Phase I Stereoselective Biotransformation of Chiral Polychlorinated Biphenyls by Rat Cytochrome P-450 2B1 Isozyme
resolves10.1124/jpet.117.247296
Establishing Transcriptional Signatures to Differentiate PXR-, CAR-, and AhR-Mediated Regulation of Drug Metabolism and Transport Genes in Cryopreserved Human Hepatocytes
resolves10.1021/acs.est.0c01805
Mother to Fetus Transfer of Hydroxylated Polychlorinated Biphenyl Congeners (OH-PCBs) in the Japanese Macaque (<i>Macaca fuscata</i>): Extrapolation of Exposure Scenarios to Humans
resolves10.1007/s11356-017-0683-x
Atropisomers of 2,2′,3,3′,6,6′-hexachlorobiphenyl (PCB 136) exhibit stereoselective effects on activation of nuclear receptors in vitro
resolves10.1016/j.envpol.2018.02.067
In vitro profiling of toxic effects of prominent environmental lower-chlorinated PCB congeners linked with endocrine disruption and tumor promotion
resolves10.1016/S0021-9258(20)82065-1
Non-arene oxide aromatic ring hydroxylation of 2,2',5,5'-tetrachlorobiphenyl as the major metabolic pathway catalyzed by phenobarbital-induced rat liver microsomes.
resolves10.1021/acs.est.9b07693
A Global, Cross-System Meta-Analysis of Polychlorinated Biphenyl Biomagnification
resolves10.1021/acs.est.8b05503
Legacy and Currently Used Organic Contaminants in Human Hair and Hand Wipes of Female E-Waste Dismantling Workers and Workplace Dust in South China
resolves10.1021/tx1004562
Biotransformation of 2,2′,5,5′-Tetrachlorobiphenyl (PCB 52) and 3,3′,4,4′-Tetrachlorobiphenyl (PCB 77) by Liver Microsomes from Four Species of Sea Turtles
resolves10.1021/acs.est.6b00484
Sulfation of Lower Chlorinated Polychlorinated Biphenyls Increases Their Affinity for the Major Drug-Binding Sites of Human Serum Albumin
resolves10.1016/S0890-6238(02)00076-X
Effects of Aroclors and individual PCB congeners on activation of the human androgen receptor in vitro
resolves10.1016/j.ntt.2012.08.007
Using mouse models of autism spectrum disorders to study the neurotoxicology of gene–environment interactions
resolves10.2174/138920011795016818
Endogenous and Exogenous Ligands of Aryl Hydrocarbon Receptor: Current State of Art
resolves10.1289/ehp.6560
Highly chlorinated PCBs inhibit the human xenobiotic response mediated by the steroid and xenobiotic receptor (SXR).
resolves10.1007/s11356-013-1742-6
Hydroxylated polychlorinated biphenyls in the environment: sources, fate, and toxicities
resolves10.1002/jcc.21334
AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading
resolves10.1002/bms.1200040507
Identification of hydroxyhalobiphenyls as their methyl ethers by gas chromatography mass spectrometry
resolves10.1021/acs.chemrestox.6b00371
2,2′,3,5′,6-Pentachlorobiphenyl (PCB 95) Is Atropselectively Metabolized to para-Hydroxylated Metabolites by Human Liver Microsomes
resolves10.1021/acs.est.8b00612
Human Liver Microsomes Atropselectively Metabolize 2,2′,3,4′,6-Pentachlorobiphenyl (PCB 91) to a 1,2-Shift Product as the Major Metabolite
resolves10.1021/acs.est.6b05387
Microsomal Metabolism of Prochiral Polychlorinated Biphenyls Results in the Enantioselective Formation of Chiral Metabolites
resolves10.1021/acs.est.8b05250
Human CYP2A6, CYP2B6, AND CYP2E1 Atropselectively Metabolize Polychlorinated Biphenyls to Hydroxylated Metabolites
resolves10.1016/j.envres.2019.108982
Computational evaluation of interactions between organophosphate esters and nuclear hormone receptors
resolves10.1021/es802237u
Chiral Polychlorinated Biphenyls Are Biotransformed Enantioselectively by Mammalian Cytochrome P-450 Isozymes to Form Hydroxylated Metabolites
resolves10.1021/tx400229e
Oxidation of Polychlorinated Biphenyls by Liver Tissue Slices from Phenobarbital-Pretreated Mice Is Congener-Specific and Atropselective
resolves10.1021/es405433t
Microsomal Oxidation of 2,2′,3,3′,6,6′-Hexachlorobiphenyl (PCB 136) Results in Species-Dependent Chiral Signatures of the Hydroxylated Metabolites
resolves10.1021/tx200360m
2,2′,3,3′,6,6′-Hexachlorobiphenyl (PCB 136) Is Enantioselectively Oxidized to Hydroxylated Metabolites by Rat Liver Microsomes
resolves10.1073/pnas.0438010100
Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor
resolves10.1093/jb/mvr009
Structural basis of species differences between human and experimental animal CYP1A1s in metabolism of 3,3′,4,4′,5-pentachlorobiphenyl
resolves10.1021/acs.est.1c02189
Influence of Bisphenol Compounds at Nanomolar Concentrations on Chromosome Damage Induced by Metabolically Activated Carcinogens in HepG2 Cells
resolves10.1021/acs.est.0c02508
Atropselective Partitioning of Polychlorinated Biphenyls in a HepG2 Cell Culture System: Experimental and Modeling Results
resolves10.1021/acs.est.0c06983
Detection and Quantification of Polychlorinated Biphenyl Sulfates in Human Serum
The 9 references without a DOI — listed, not checked
no DOI — not checkedAtmospheric concentrations and temporal trends of polychlorinated biphenyls and organochlorine pesticides in the Arctic during
no DOI — not checkedref14
no DOI — not checkedref16
no DOI — not checkedref20
no DOI — not checkedref21
no DOI — not checkedref22
no DOI — not checkedComparative transcriptomic analysis reveals reproductive impairments caused by PCBs and OH-PCBs through the dysregulation of ER and AR signaling
no DOI — not checkedref57
no DOI — not checkedEnantioselective Dechlorination of Polychlorinated Biphenyls in Dehalococcoides mccartyi CG1
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