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An Oncolytic Vaccinia Virus Expressing EpCAM Bispecific T-Cell Engager Enhances Immune Response in Solid Tumors

https://doi.org/10.2139/ssrn.4123194
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30/30 checkable references clean · checked 2026-07-23

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

6 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 30 checked references that resolve
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Intratumoral Delivery of a PD-1–Blocking scFv Encoded in Oncolytic HSV-1 Promotes Antitumor Immunity and Synergizes with TIGIT Blockade
resolves10.1038/nrd4663
Oncolytic viruses: a new class of immunotherapy drugs
resolves10.1016/j.ymthe.2018.04.001
Oncolytic Virus Combination Therapy: Killing One Bird with Two Stones
resolves10.1038/nm.3089
Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer
resolves10.1016/S1470-2045(08)70107-4
Use of a targeted oncolytic poxvirus, JX-594, in patients with refractory primary or metastatic liver cancer: a phase I trial
resolves10.1016/j.omto.2019.03.005
The Enhanced Tumor Specificity of TG6002, an Armed Oncolytic Vaccinia Virus Deleted in Two Genes Involved in Nucleotide Metabolism
resolves10.1016/j.omto.2020.08.020
Preclinical Evaluation of the Oncolytic Vaccinia Virus TG6002 by Translational Research on Canine Breast Cancer
resolves10.1016/j.omto.2020.08.011
High Oncolytic Activity of a Double-Deleted Vaccinia Virus Copenhagen Strain against Malignant Pleural Mesothelioma
resolves10.1089/hum.2020.050
Generation of a Novel Oncolytic Vaccinia Virus Using the IHD-W Strain
resolves10.1038/s41571-020-0347-5
T cell-engaging therapies — BiTEs and beyond
resolves10.1016/j.molimm.2005.07.034
MT110: A novel bispecific single-chain antibody construct with high efficacy in eradicating established tumors
resolves10.1002/ijc.20908
Serial killing of tumor cells by cytotoxic T cells redirected with a CD19‐/CD3‐bispecific single‐chain antibody construct
resolves10.1007/s00262-003-0496-2
T-cell-mediated lysis of B cells induced by a CD19xCD3 bispecific single-chain antibody is perforin dependent and death receptor independent
resolves10.1038/s41375-018-0014-3
Simultaneous multiple interaction T-cell engaging (SMITE) bispecific antibodies overcome bispecific T-cell engager (BiTE) resistance via CD28 co-stimulation
resolves10.1158/0008-5472.CAN-09-0547
Bispecific T-Cell Engaging Antibodies for Cancer Therapy
resolves10.1002/cpt.651
Translation and Clinical Development of Bispecific T‐cell Engaging Antibodies for Cancer Treatment
resolves10.1016/j.pharmthera.2017.12.002
Bispecific antibodies for cancer therapy: A review
resolves10.1016/0167-5699(96)80606-2
The expanding universe of T-cell subsets: Th1, Th2 and more
resolves10.1016/j.jhep.2009.10.026
EpCAM, a new marker for cancer stem cells in hepatocellular carcinoma
resolves10.1016/S0140-6736(00)03312-2
Ep-CAM overexpression in breast cancer as a predictor of survival
resolves10.1016/j.humpath.2003.08.026
Frequent EpCam protein expression in human carcinomas
resolves10.1038/mt.2013.240
T-cell Engager-armed Oncolytic Vaccinia Virus Significantly Enhances Antitumor Therapy
resolves10.1158/0008-5472.CAN-16-1708
Oncolytic Adenoviral Delivery of an EGFR-Targeting T-cell Engager Improves Antitumor Efficacy
resolves10.15252/emmm.201707567
Oncolytic adenovirus expressing bispecific antibody targets T‐cell cytotoxicity in cancer biopsies
resolves10.1016/0167-5699(94)90080-9
The B7 and CD28 receptor families
resolves10.1097/CJI.0b013e31815ba792
Phase II Trial of B7-1 (CD-86) Transduced, Cultured Autologous Tumor Cell Vaccine Plus Subcutaneous Interleukin-2 for Treatment of Stage IV Renal Cell Carcinoma
resolves10.1158/1078-0432.CCR-08-0276
Combination Chemotherapy and ALVAC-CEA/B7.1 Vaccine in Patients with Metastatic Colorectal Cancer
resolves10.1007/s00432-010-0905-9
Triple expression of B7-1, B7-2 and 4-1BBL enhanced antitumor immune response against mouse H22 hepatocellular carcinoma
resolves10.1038/nm0697-682
Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors
resolves10.1016/j.jss.2011.03.067
Combinatorial Therapy for Liver Metastatic Colon Cancer: Dendritic Cell Vaccine and Low-Dose Agonistic Anti-4-1BB Antibody Co-Stimulatory Signal
The 6 references without a DOI — listed, not checked
no DOI — not checkedVaccinia virus-mediated cancer immunotherapy: cancer vaccines and oncolytics
no DOI — not checkedBiTE: Teaching antibodies to engage T-cells for cancer therapy
no DOI — not checkedAnti-CD20/CD3 T cell-dependent bispecific antibody for the treatment of B cell malignancies
no DOI — not checkedCombination therapy with T cell engager and PD-L1 blockade enhances the antitumor potency of T cells as predicted by a QSP model
no DOI — not checkedA multicenter phase 1 study of solitomab (MT110, AMG 110), a bispecific EpCAM/CD3 T-cell engager (BiTE(R)) antibody construct, in patients with refractory solid tumors
no DOI — not checkedBispecific T cell engagers and their synergistic tumor immunotherapy with oncolytic viruses
What this badge says. CiteStamped means the CHECKABLE references of this work were clean at the dated check: each resolved to a known work in a public registry, and none carried a retraction notice at that time. It says nothing about the quality, findings, or importance of the work itself, and nothing about references deposited without a DOI.

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