Reference health
ACSS2-Mediated Deacetylation of Autophagy Proteins Inhibits Malignancy of Epithelial Ovarian Cancer by Inhibiting Glycolysis
1 of 44 checkable references need attention · checked 2026-07-23
At the dated check, the references listed below either did not resolve in Crossref or DataCite, or carried a retraction notice. Each one is shown with the registry record that put it there.
15 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
References needing attention
marked retracted by the publisher10.3389/fphar.2020.572616
Paeonol Suppresses Proliferation and Motility of Non-Small-Cell Lung Cancer Cells by Disrupting STAT3/NF-κB Signaling
The 43 checked references that resolve
resolves10.1126/science.1160809
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
resolves10.1016/j.cell.2018.08.040
Acetate Production from Glucose and Coupling to Mitochondrial Metabolism in Mammals
resolves10.1146/annurev-cellbio-092910-154237
Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation
resolves10.1016/j.ccell.2014.12.002
Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress
resolves10.1016/j.celrep.2016.12.055
Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation
resolves10.1002/cam4.1295
Mitochondrial Acetyl‐CoA Synthetase 3 is Biosignature of Gastric Cancer Progression
resolves10.1158/0008-5472.CAN-20-1847
Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth
resolves10.1016/j.cmet.2020.12.011
Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma
resolves10.1080/15548627.2017.1349581
Local histone acetylation by ACSS2 promotes gene transcription for lysosomal biogenesis and autophagy
resolves10.1016/j.phymed.2014.02.012
Paeonol reverses paclitaxel resistance in human breast cancer cells by regulating the expression of transgelin 2
resolves10.1080/14767058.2018.1487396
Paeonol attenuates isoflurane anesthesia-induced hippocampal neurotoxicity via modulation of JNK/ERK/P38MAPK pathway and regulates histone acetylation in neonatal rat
resolves10.1016/j.bbrc.2019.08.096
RSL3 induced autophagic death in glioma cells via causing glycolysis dysfunction
resolves10.2967/jnumed.115.158808
<sup>18</sup>F-FDG PET/CT and PET/MRI Perform Equally Well in Cancer: Evidence from Studies on More Than 2,300 Patients
resolves10.2217/hep.15.36
Targeting glucose metabolism in cancer: a new class of agents for loco-regional and systemic therapy of liver cancer and beyond?
resolves10.1038/aps.2016.47
Anticancer strategies based on the metabolic profile of tumor cells: therapeutic targeting of the Warburg effect
resolves10.2174/1568026618666180523111351
Inhibition of Glycolysis and Glutaminolysis: An Emerging Drug Discovery Approach to Combat Cancer
resolves10.2967/jnumed.109.062703
The Importance of Acetyl Coenzyme A Synthetase for <sup>11</sup>C-Acetate Uptake and Cell Survival in Hepatocellular Carcinoma
resolves10.2967/jnumed.113.131169
<sup>11</sup>C-Acetate PET/CT for Metabolic Characterization of Multiple Myeloma: A Comparative Study with <sup>18</sup>F-FDG PET/CT
resolves10.1021/acsmedchemlett.9b00295
Inhibition of ACSS2 for Treatment of Cancer and Neuropsychiatric Diseases
resolves10.1073/pnas.1807305115
Metabolic network-based stratification of hepatocellular carcinoma reveals three distinct tumor subtypes
resolves10.1016/j.molcel.2017.04.026
Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy
resolves10.1016/j.freeradbiomed.2020.10.009
miR-15a-5p inhibits metastasis and lipid metabolism by suppressing histone acetylation in lung cancer
resolves10.3389/fnut.2021.588466
Acetate Induces Growth Arrest in Colon Cancer Cells Through Modulation of Mitochondrial Function
resolves10.1016/j.envpol.2021.116504
Cadmium promotes breast cancer cell proliferation, migration and invasion by inhibiting ACSS2/ATG5-mediated autophagy
resolves10.1371/journal.pone.0190241
Coordinate regulation of stress signaling and epigenetic events by Acss2 and HIF-2 in cancer cells
resolves10.1016/j.molcel.2014.12.013
Deacetylation of Nuclear LC3 Drives Autophagy Initiation under Starvation
resolves10.1371/journal.pone.0116515
The Acetate/ACSS2 Switch Regulates HIF-2 Stress Signaling in the Tumor Cell Microenvironment
resolves10.1016/j.cell.2014.11.025
Acetate Is a Bioenergetic Substrate for Human Glioblastoma and Brain Metastases
The 15 references without a DOI — listed, not checked
no DOI — not checkedThe Warburg Effect: How Does it Benefit Cancer Cells?
no DOI — not checkedref19
no DOI — not checkedref21
no DOI — not checkedPaeonol induces apoptosis of ovarian cancer cells through the AKT/GSK-3? signaling pathway
no DOI — not checkedCharacterization of novel alpha-Mangostin and Paeonol derivatives with cancer-selective cytotoxicity
no DOI — not checkedPaeonol induces cytoprotective autophagy via blocking the Akt/mTOR pathway in ovarian cancer cells
no DOI — not checkedPaeonol Ameliorates Glucose and Lipid Metabolism in Experimental Diabetes by Activating Akt
no DOI — not checkedChloropupukeananin and Pestalofone C Regulate Autophagy through AMPK and Glycolytic Pathway
no DOI — not checkedTargeting glucose metabolism to suppress cancer progression: prospective of anti-glycolytic cancer therapy
no DOI — not checkedTissue Distribution and Excretion of Paeonol and Its Major Metabolites in Rats Provide a Further Insight Into Paeonol Effectiveness
no DOI — not checkedAcetyl Coenzyme A Synthase 2 Acts as a Prognostic Biomarker Associated with Immune Infiltration in Cervical Squamous Cell Carcinoma
no DOI — not checkedAcetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia
no DOI — not checkedRegulation of autophagy by protein methylation and acetylation in cancer
no DOI — not checkedAcetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth
no DOI — not checkedATG5 were assessed via immunoprecipitation analysis in SKOV3 cells after 2DG treatment or ACSS2 knockdown. (D) Immunofluorescence staining to detect the co-localization of ACSS2 and SIRT1. (E) CUT&Tag analysis of the binding peak of SIRT1 enriched in ACSS2. (F) Interactions between ACSS2 and SIRT1 as well as between SIRT1 and ATG5 in SKOV3 cells. (G) Immunoprecipitation analysis for assessing ATG5 and ATG2B acetylation levels after SIRT1 knockdown or SIRT1 co-knockdown with ACSS2 in SKOV3 cells
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