Reference health
Brain Amyloid- ß Accumulation in AD Mouse Models Modified by Their Altered Gene Expression in the Presence of Human apoE Isoforms Through Aging Process
1 of 63 checkable references need attention · checked 2026-07-22
At the dated check, the references listed below either did not resolve in Crossref or DataCite, or carried a retraction notice. Each one is shown with the registry record that put it there.
14 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
References needing attention
marked retracted — notice via Crossref, record curated by Retraction Watch10.1016/j.brainresbull.2021.06.023
RETRACTED: MicroRNA-16-5p/BTG2 axis affects neurological function, autophagy and apoptosis of hippocampal neurons in Alzheimer's disease
The 62 checked references that resolve
resolves10.1002/alz.12256
Reactive or transgenic increase in microglial TYROBP reveals a TREM2‐independent TYROBP–APOE link in wild‐type and Alzheimer's‐related mice
resolves10.1038/s41467-020-17405-z
Multiscale causal networks identify VGF as a key regulator of Alzheimer’s disease
resolves10.1007/s12031-018-1217-9
Apolipoprotein D Upregulation in Alzheimer’s Disease but Not Frontotemporal Dementia
resolves10.1186/1750-1326-3-13
Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease
resolves10.1126/scitranslmed.3002156
Human apoE Isoforms Differentially Regulate Brain Amyloid-β Peptide Clearance
resolves10.1038/s41598-017-17999-3
Comparative profiling of cortical gene expression in Alzheimer’s disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation
resolves10.1074/jbc.R800015200
The Role of Amyloid Precursor Protein Processing by BACE1, the β-Secretase, in Alzheimer Disease Pathophysiology
resolves10.1126/science.8346443
Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families
resolves10.1016/j.dadm.2019.03.004
Altered expression of insulin‐degrading enzyme and regulator of calcineurin in the rat intracerebral streptozotocin model and human apolipoprotein E‐ε4–associated Alzheimer's disease
resolves10.1073/pnas.1018140108
Calreticulin chaperones regulate functional expression of vomeronasal type 2 pheromone receptors
resolves10.1126/science.1168979
A Recessive Mutation in the APP Gene with Dominant-Negative Effect on Amyloidogenesis
resolves10.1186/1471-2105-10-48
GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists
resolves10.1093/hmg/ddab115
High-fat diet–induced activation of SGK1 promotes Alzheimer’s disease–associated tau pathology
resolves10.1006/nbdi.2002.0483
Human and Murine ApoE Markedly Alters Aβ Metabolism before and after Plaque Formation in a Mouse Model of Alzheimer's Disease
resolves10.1523/JNEUROSCI.1542-12.2012
Apolipoprotein E, Especially Apolipoprotein E4, Increases the Oligomerization of Amyloid β Peptide
resolves10.1074/jbc.M508781200
The Absence of ABCA1 Decreases Soluble ApoE Levels but Does Not Diminish Amyloid Deposition in Two Murine Models of Alzheimer Disease
resolves10.1523/JNEUROSCI.3135-07.2007
The Metalloprotease Inhibitor TIMP-3 Regulates Amyloid Precursor Protein and Apolipoprotein E Receptor Proteolysis
resolves10.1172/JCI6179
Expression of human apolipoprotein E reduces amyloid-β deposition in a mouse model of Alzheimer's disease
resolves10.1038/nature11283
A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline
resolves10.1016/j.cell.2017.05.018
A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease
resolves10.1046/j.1471-4159.1997.69052026.x
Degradation of Tau by Lysosomal Enzyme Cathepsin D: Implication for Alzheimer Neurofibrillary Degeneration
resolves10.1074/jbc.M116.744722
Alternative Selection of β-Site APP-Cleaving Enzyme 1 (BACE1) Cleavage Sites in Amyloid β-Protein Precursor (APP) Harboring Protective and Pathogenic Mutations within the Aβ Sequence
resolves10.1074/jbc.M504513200
Lack of ABCA1 Considerably Decreases Brain ApoE Level and Increases Amyloid Deposition in APP23 Mice
resolves10.1186/1750-1326-5-35
Increased amyloidogenic processing of transgenic human APP in X11-like deficient mouse brain
resolves10.1038/227680a0
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
resolves10.1016/j.neurobiolaging.2015.02.010
Apolipoprotein D modulates amyloid pathology in APP/PS1 Alzheimer's disease mice
resolves10.1016/j.neuron.2022.03.004
ApoE Cascade Hypothesis in the pathogenesis of Alzheimer’s disease and related dementias
resolves10.1093/brain/awx066
Gene-based association studies report genetic links for clinical subtypes of frontotemporal dementia
resolves10.1111/j.1471-4159.2009.06399.x
Suppression of APP‐containing vesicle trafficking and production of β‐amyloid by AID/DHHC‐12 protein
resolves10.1093/jnen/62.3.280
Increased Vulnerability to Focal Ischemic Brain Injury in Human Apolipoprotein E4 Knock-In Mice
resolves10.1038/ng0892-345
A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N–terminus of β–amyloid
resolves10.1007/BF03401803
The Cytoplasmic Domain of Alzheimer’s Amyloid Precursor Protein Is Phosphorylated at Thr654, Ser655, and Thr668 in Adult Rat Brain and Cultured Cells
resolves10.1016/j.neurobiolaging.2005.01.004
Insulin, insulin-degrading enzyme and amyloid-β peptide in Alzheimer's disease: review and hypothesis
resolves10.1016/j.neurobiolaging.2003.12.023
ApoE genotype accounts for the vast majority of AD risk and AD pathology
resolves10.1523/JNEUROSCI.1972-08.2008
Impact of Apolipoprotein E (ApoE) Polymorphism on Brain ApoE Levels
resolves10.1007/s40142-018-0132-2
Mitochondria and Alzheimer’s Disease: the Role of Mitochondrial Genetic Variation
resolves10.1038/nm1206
Somatostatin regulates brain amyloid β peptide Aβ42 through modulation of proteolytic degradation
resolves10.1016/j.neurobiolaging.2009.10.011
Cathepsin D gene and the risk of Alzheimer's disease: A population-based study and meta-analysis
resolves10.1016/j.neurobiolaging.2006.04.005
Gender-specific association of ATP-binding cassette transporter 1 (ABCA1) polymorphisms with the risk of late-onset Alzheimer's disease
resolves10.1016/j.bbadis.2013.09.010
The Alzheimer's disease mitochondrial cascade hypothesis: Progress and perspectives
resolves10.1074/jbc.273.11.6277
Cleavage of Alzheimer's Amyloid Precursor Protein (APP) by Secretases Occurs after O-Glycosylation of APP in the Protein Secretory Pathway
resolves10.1074/jbc.M508780200
Deletion of Abca1 Increases Aβ Deposition in the PDAPP Transgenic Mouse Model of Alzheimer Disease
resolves10.3389/fnagi.2019.00060
Hapln2 in Neurological Diseases and Its Potential as Therapeutic Target
resolves10.2353/ajpath.2009.090044
Independent Effects of Intra- and Extracellular Aβ on Learning-Related Gene Expression
resolves10.1016/j.cell.2011.09.036
Arc/Arg3.1 Regulates an Endosomal Pathway Essential for Activity-Dependent β-Amyloid Generation
resolves10.1523/JNEUROSCI.5476-05.2006
Profile and Regulation of Apolipoprotein E (ApoE) Expression in the CNS in Mice with Targeting of Green Fluorescent Protein Gene to the ApoE Locus
resolves10.1016/j.intimp.2021.107808
Andrographolide ameliorates neuroinflammation in APP/PS1 transgenic mice
resolves10.1016/j.neuron.2020.02.034
Alzheimer’s Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways
resolves10.1002/emmm.201100138
Amyloid precursor protein mutation E682K at the alternative β‐secretase cleavage β′‐site increases Aβ generation†
resolves10.1016/j.neuroscience.2006.08.019
Cathepsin D-mediated proteolysis of apolipoprotein E: Possible role in Alzheimer’s disease
The 14 references without a DOI — listed, not checked
no DOI — not checkedref1
no DOI — not checkedEvaluation of cerebrospinal fluid glycoprotein NMB (GPNMB) as a potential biomarker for Alzheimer's disease
no DOI — not checkedApoE4 disrupts interaction of sortilin with fatty acid-binding protein 7 essential to promote lipid signaling
no DOI — not checkedref8
no DOI — not checkedref15
no DOI — not checkedAlzheimer Genetic Analysis Group
no DOI — not checkedAnalyzing the genes related to Alzheimer's disease via a network and pathway-based approach
no DOI — not checkedA novel ARC gene polymorphism is associated with reduced risk of Alzheimer's disease
no DOI — not checkedSerum calreticulin is a negative biomarker in patients with Alzheimer's disease
no DOI — not checkedThe glia-neuron lactate shuttle and elevated ROS promote lipid synthesis in neurons and lipid droplet accumulation in glia via apoE/D
no DOI — not checkedNeuronal ROS-induced glial lipid droplet formation is altered by loss of Alzheimer's disease-associated genes
no DOI — not checkedTCC: an R package for comparing tag count data with robust normalization strategies
no DOI — not checkedref70
no DOI — not checkedref74
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