Reference health

Interleukin-18-Primed Human Umbilical Cord-Mesenchymal Stem Cells Achieve Superior Therapeutic Efficacy for Severe Viral Pneumonia Via Enhancing T-Cell Immunosuppression

https://doi.org/10.2139/ssrn.4191376
CiteStamped reference-health badge
41/41 checkable references clean · checked 2026-08-29

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

9 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 41 checked references that resolve
resolves10.1002/sctm.20-0472
Umbilical cord mesenchymal stem cells for COVID-19 acute respiratory distress syndrome: A double-blind, phase 1/2a, randomized controlled trial
resolves10.1001/jama.2020.6775
Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area
resolves10.1073/pnas.1601911113
Human mesenchymal stromal cells reduce influenza A H5N1-associated acute lung injury in vitro and in vivo
resolves10.1093/infdis/jiy478
Therapeutic Implications of Human Umbilical Cord Mesenchymal Stromal Cells in Attenuating Influenza A(H5N1) Virus–Associated Acute Lung Injury
resolves10.1186/s12879-020-05525-2
Bone marrow-derived mesenchymal stem cells attenuate pulmonary inflammation and lung damage caused by highly pathogenic avian influenza A/H5N1 virus in BALB/c mice
resolves10.1371/journal.pone.0071761
Mesenchymal Stromal (Stem) Cell Therapy Fails to Improve Outcomes in Experimental Severe Influenza
resolves10.1152/ajplung.00110.2014
Influenza causes prolonged disruption of the alveolar-capillary barrier in mice unresponsive to mesenchymal stem cell therapy
resolves10.1164/rccm.201802-0356OC
Identification and Modulation of Microenvironment Is Crucial for Effective Mesenchymal Stromal Cell Therapy in Acute Lung Injury
resolves10.1016/j.stem.2013.09.006
Mesenchymal Stromal Cells: Sensors and Switchers of Inflammation
resolves10.1002/stem.2075
Interleukin-17A-Induced Human Mesenchymal Stem Cells Are Superior Modulators of Immunological Function
resolves10.1073/pnas.1617933114
Morphological features of IFN-γ–stimulated mesenchymal stromal cells predict overall immunosuppressive capacity
resolves10.1186/s13287-017-0531-4
Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro
resolves10.1136/annrheumdis-2020-217798
Combination of human umbilical cord mesenchymal stem (stromal) cell transplantation with IFN-γ treatment synergistically improves the clinical outcomes of patients with rheumatoid arthritis
resolves10.1002/jcp.24330
Activation and promotion of adipose stem cells by tumour necrosis factor‐alpha preconditioning for bone regeneration
resolves10.1089/ten.tea.2016.0548
Priming Adipose Stem Cells with Tumor Necrosis Factor-Alpha Preconditioning Potentiates Their Exosome Efficacy for Bone Regeneration
resolves10.1002/stem.698
Pretreatment with Interferon-γ Enhances the Therapeutic Activity of Mesenchymal Stromal Cells in Animal Models of Colitis
resolves10.1016/j.ebiom.2018.01.002
Enhanced Immunosuppressive Properties of Human Mesenchymal Stem Cells Primed by Interferon-γ
resolves10.1016/j.jid.2019.07.721
IL-1β–Primed Mesenchymal Stromal Cells Improve Epidermal Substitute Engraftment and Wound Healing via Matrix Metalloproteinases and Transforming Growth Factor-β1
resolves10.1016/j.kint.2017.08.030
IL-17A improves the efficacy of mesenchymal stem cells in ischemic-reperfusion renal injury by increasing Treg percentages by the COX-2/PGE2 pathway
resolves10.1096/fj.201900047R
TNF‐α/IL‐1β—licensed mesenchymal stromal cells promote corneal allograft survival <i>via</i> myeloid cell‐mediated induction of Foxp3 <sup>+</sup> regulatory T cells in the lung
resolves10.1038/mt.2011.189
Human MSC Suppression Correlates With Cytokine Induction of Indoleamine 2,3-Dioxygenase and Bystander M2 Macrophage Differentiation
resolves10.1016/j.ymthe.2020.05.023
TGF-β1-Licensed Murine MSCs Show Superior Therapeutic Efficacy in Modulating Corneal Allograft Immune Rejection In Vivo
resolves10.1007/s11010-013-1683-x
CX43 change in LPS preconditioning against apoptosis of mesenchymal stem cells induced by hypoxia and serum deprivation is associated with ERK signaling pathway
resolves10.1093/rheumatology/kez631
Metformin enhances the immunomodulatory potential of adipose-derived mesenchymal stem cells through STAT1 in an animal model of lupus
resolves10.1038/378088a0
Cloning of a new cytokine that induces IFN-γ production by T cells
resolves10.1002/jcp.30008
IL‐18 and infections: Is there a role for targeted therapies?
resolves10.1146/annurev.immunol.19.1.423
Interleukin-18 Regulates Both Th1 and Th2 Responses
resolves10.1152/ajpheart.00158.2018
Inflammasome, pyroptosis, and cytokines in myocardial ischemia-reperfusion injury
resolves10.1046/j.1365-2249.2003.02179.x
Raised serum levels of interleukin-18 is associated with disease progression and may contribute to virological treatment failure in HIV-1-infected patients
resolves10.1093/infdis/jis335
IL-18 Serum Concentration Is Markedly Elevated in Acute EBV Infection and Can Serve as a Marker for Disease Severity
resolves10.1002/jmv.20255
An interferon‐γ‐related cytokine storm in SARS patients
resolves10.3389/fcell.2021.722953
Human Platelet Lysate Maintains Stemness of Umbilical Cord-Derived Mesenchymal Stromal Cells and Promote Lung Repair in Rat Bronchopulmonary Dysplasia
resolves10.1016/j.ymthe.2020.01.011
Cardiac Nestin+ Mesenchymal Stromal Cells Enhance Healing of Ischemic Heart through Periostin-Mediated M2 Macrophage Polarization
resolves10.4049/jimmunol.0903143
Mesenchymal Stem Cells Protect Breast Cancer Cells through Regulatory T Cells: Role of Mesenchymal Stem Cell-Derived TGF-β
resolves10.1016/j.cyto.2021.155593
The cytokine storms of COVID-19, H1N1 influenza, CRS and MAS compared. Can one sized treatment fit all?
resolves10.1084/jem.20201707
Inflammasomes are activated in response to SARS-CoV-2 infection and are associated with COVID-19 severity in patients
resolves10.5858/arpa.2015-0519-RA
Acute Lung Injury: A Clinical and Molecular Review
resolves10.1007/s00540-012-1409-3
Interleukin-18 levels reflect the long-term prognosis of acute lung injury and acute respiratory distress syndrome
resolves10.3389/fimmu.2013.00289
Interleukin-18 and IL-18 Binding Protein
resolves10.1161/CIRCRESAHA.120.315937
Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease
resolves10.1371/journal.pone.0010088
A New Mesenchymal Stem Cell (MSC) Paradigm: Polarization into a Pro-Inflammatory MSC1 or an Immunosuppressive MSC2 Phenotype
The 9 references without a DOI — listed, not checked
no DOI — not checkedEffect of human umbilical cord-derived mesenchymal stem cells on lung damage in severe COVID-19 patients: a randomized, double-blind, placebo-controlled phase 2 trial
no DOI — not checkedHuman umbilical cord-derived mesenchymal stem cell therapy in patients with COVID-19: a phase 1 clinical trial
no DOI — not checkedMesenchymal stromal cell treatment prevents H9N2 avian influenza virus-induced acute lung injury in mice
no DOI — not checkedClinical Study of Mesenchymal Stem Cell Treatment for Acute Respiratory Distress Syndrome Induced by Epidemic Influenza A (H7N9) Infection: A Hint for COVID-19
no DOI — not checkedEvaluation of the safety and efficacy of using human menstrual blood-derived mesenchymal stromal cells in treating severe and critically ill COVID-19 patients: An exploratory clinical trial
no DOI — not checkedInterleukin-25 primed mesenchymal stem cells achieve better therapeutic effects on dextran sulfate sodium-induced colitis via inhibiting Th17 immune response and inducing T regulatory cell phenotype
no DOI — not checkedTNF-? and IFN-? Participate in Improving the Immunoregulatory Capacity of Mesenchymal Stem/Stromal Cells: Importance of Cell-Cell Contact and Extracellular Vesicles
no DOI — not checkedref32
no DOI — not checkedIL-18/IL-18BP and IL-22/IL-22BP: Two interrelated couples with therapeutic potential
What this badge says. CiteStamped means the CHECKABLE references of this work were clean at the dated check: each resolved to a known work in a public registry, and none carried a retraction notice at that time. It says nothing about the quality, findings, or importance of the work itself, and nothing about references deposited without a DOI.

checked 2026-08-29 — re-checked daily as this page is visited; titles and statuses come from Crossref and DataCite and are not part of the signed record

Embed this badge

Both snippets point at the live badge image and link back to this page. The badge re-renders from the daily check, so an embed never goes stale by more than a day of visits.

<a href="https://citestamp.com/citestamped/10.2139/ssrn.4191376"><img src="https://citestamp.com/citestamped/10.2139/ssrn.4191376/badge.svg" alt="CiteStamped reference-health badge" width="460" height="64"></a>
[![CiteStamped reference-health badge](https://citestamp.com/citestamped/10.2139/ssrn.4191376/badge.svg)](https://citestamp.com/citestamped/10.2139/ssrn.4191376)