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Further Preclinical Characterization of Molnupiravir Against SARS-CoV-2: Antiviral Activity Determinants and Viral Genome Alteration Patterns
29/29 checkable references clean · checked 2026-07-24
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
14 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 29 checked references that resolve
resolves10.1177/095632020401500102
Inhibition of Severe Acute Respiratory Syndrome-Associated Coronavirus (SARSCoV) by Calpain Inhibitors and β-D-N<sup>4</sup>-Hydroxycytidine
resolves10.1016/S0140-6736(22)02597-1
Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial
resolves10.1056/EVIDoa2100043
Phase 2/3 Trial of Molnupiravir for Treatment of Covid-19 in Nonhospitalized Adults
resolves10.1016/j.antiviral.2021.105212
Hydroxychloroquine and azithromycin used alone or combined are not effective against SARS-CoV-2 ex vivo and in a hamster model
resolves10.1038/s41564-020-00835-2
Therapeutically administered ribonucleoside analogue MK-4482/EIDD-2801 blocks SARS-CoV-2 transmission in ferrets
resolves10.1038/s41467-022-34839-9
Characterisation of SARS-CoV-2 genomic variation in response to molnupiravir treatment in the AGILE Phase IIa clinical trial
resolves10.1128/AAC.02395-16
Characterization of β-
<scp>d</scp>
-
<i>N</i>
<sup>4</sup>
-Hydroxycytidine as a Novel Inhibitor of Chikungunya Virus
resolves10.3390/microorganisms10071475
The Combination of Molnupiravir with Nirmatrelvir or GC376 Has a Synergic Role in the Inhibition of SARS-CoV-2 Replication In Vitro
resolves10.1056/NEJMoa2116044
Molnupiravir for Oral Treatment of Covid-19 in Nonhospitalized Patients
resolves10.1016/j.antiviral.2022.105430
Combination therapy with nirmatrelvir and molnupiravir improves the survival of SARS-CoV-2 infected mice
resolves10.1016/j.antiviral.2022.105492
Evaluation of molnupiravir (EIDD-2801) efficacy against SARS-CoV-2 in the rhesus macaque model
resolves10.1073/pnas.2014441117
Favipiravir at high doses has potent antiviral activity in SARS-CoV-2−infected hamsters, whereas hydroxychloroquine lacks activity
resolves10.1093/jac/dkab318
Optimal dose and safety of molnupiravir in patients with early SARS-CoV-2: a Phase I, open-label, dose-escalating, randomized controlled study
resolves10.1002/slct.201703052
Selective Inhibition of
<i>Enterovirus A</i>
Species Members’ Reproduction by Furano[2, 3‐
<i>d</i>
]pyrimidine Nucleosides Revealed by Antiviral Activity Profiling against (+)ssRNA Viruses
resolves10.1016/S2213-2600(14)70041-4
Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data
resolves10.1002/rmv.2133
Remdesivir: A beacon of hope from Ebola virus disease to <scp>COVID</scp>‐19
resolves10.1016/j.antiviral.2019.104597
The prophylactic and therapeutic activity of a broadly active ribonucleoside analog in a murine model of intranasal venezuelan equine encephalitis virus infection
resolves10.1016/j.xcrm.2020.100059
Characterization and Treatment of SARS-CoV-2 in Nasal and Bronchial Human Airway Epithelia
resolves10.1038/s41467-021-22580-8
Orally delivered MK-4482 inhibits SARS-CoV-2 replication in the Syrian hamster model
resolves10.15252/emmm.202013105
A comparative analysis of remdesivir and other repurposed antivirals against SARS‐CoV‐2
resolves10.1128/AAC.47.1.244-254.2003
Ribonucleoside Analogue That Blocks Replication of Bovine Viral Diarrhea and Hepatitis C Viruses in Culture
resolves10.1358/dnp.2009.22.2.1343228
The value of drug repositioning in the current pharmaceutical market
resolves10.1016/j.antiviral.2021.105137
Preclinical evaluation of Imatinib does not support its use as an antiviral drug against SARS-CoV-2
resolves10.1038/s41586-021-03312-w
SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801
resolves10.1002/em.22471
Human genetic risk of treatment with antiviral nucleoside analog drugs that induce lethal mutagenesis: the special case of molnupiravir
The 14 references without a DOI — listed, not checked
no DOI — not checkedref1
no DOI — not checked2022a. The SARS-CoV-2 Alpha variant exhibits comparable fitness to the D614G strain in a Syrian hamster model
no DOI — not checkedA robust SARS-CoV-2 replication model in primary human epithelial cells at the air liquid interface to assess antiviral agents
no DOI — not checkedPre-clinical evaluation of antiviral activity of nitazoxanide against SARS-CoV-2
no DOI — not checkedSARS-CoV-2 VOC type and biological sex affect molnupiravir efficacy in severe COVID-19 dwarf hamster model
no DOI — not checkedref23
no DOI — not checkedref24
no DOI — not checkedInhibition of Human Coronavirus NL63 Infection at Early Stages of the Replication Cycle
no DOI — not checkedA molnupiravir-associated mutational signature in global SARS-CoV-2 genomes
no DOI — not checkedAn orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice
no DOI — not checkedCharacterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia
no DOI — not checked2018. ?-D -N 4 -Hydroxycytidine Is a Potent Anti-alphavirus Compound That Induces a High Level of Mutations in the Viral Genome
no DOI — not checkedOrally Efficacious Broad-Spectrum Ribonucleoside Analog Inhibitor of Influenza and Respiratory Syncytial Viruses
no DOI — not checkedIs Also Mutagenic To Mammalian Cells
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