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Further Preclinical Characterization of Molnupiravir Against SARS-CoV-2: Antiviral Activity Determinants and Viral Genome Alteration Patterns
29/29 checkable references clean · checked 2026-07-24
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The 29 checked references that resolve
resolves10.1177/095632020401500102Inhibition of Severe Acute Respiratory Syndrome-Associated Coronavirus (SARSCoV) by Calpain Inhibitors and β-D-N<sup>4</sup>-Hydroxycytidine
resolves10.1016/S0140-6736(22)02597-1Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial
resolves10.1056/EVIDoa2100043Phase 2/3 Trial of Molnupiravir for Treatment of Covid-19 in Nonhospitalized Adults
resolves10.1016/j.antiviral.2021.105212Hydroxychloroquine and azithromycin used alone or combined are not effective against SARS-CoV-2 ex vivo and in a hamster model
resolves10.3851/IMP2229Antiviral Activity of Nucleoside Analogues against Norovirus
resolves10.1038/s41564-020-00835-2Therapeutically administered ribonucleoside analogue MK-4482/EIDD-2801 blocks SARS-CoV-2 transmission in ferrets
resolves10.1038/s41467-022-34839-9Characterisation of SARS-CoV-2 genomic variation in response to molnupiravir treatment in the AGILE Phase IIa clinical trial
resolves10.1128/AAC.02395-16Characterization of β-
<scp>d</scp>
-
<i>N</i>
<sup>4</sup>
-Hydroxycytidine as a Novel Inhibitor of Chikungunya Virus
resolves10.3390/microorganisms10071475The Combination of Molnupiravir with Nirmatrelvir or GC376 Has a Synergic Role in the Inhibition of SARS-CoV-2 Replication In Vitro
resolves10.1073/pnas.2014441117Favipiravir at high doses has potent antiviral activity in SARS-CoV-2−infected hamsters, whereas hydroxychloroquine lacks activity
resolves10.1093/jac/dkab318Optimal dose and safety of molnupiravir in patients with early SARS-CoV-2: a Phase I, open-label, dose-escalating, randomized controlled study
resolves10.1002/slct.201703052Selective Inhibition of
<i>Enterovirus A</i>
Species Members’ Reproduction by Furano[2, 3‐
<i>d</i>
]pyrimidine Nucleosides Revealed by Antiviral Activity Profiling against (+)ssRNA Viruses
resolves10.1016/S2213-2600(14)70041-4Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data
resolves10.1002/rmv.2133Remdesivir: A beacon of hope from Ebola virus disease to <scp>COVID</scp>‐19
resolves10.1016/j.antiviral.2019.104597The prophylactic and therapeutic activity of a broadly active ribonucleoside analog in a murine model of intranasal venezuelan equine encephalitis virus infection
resolves10.3390/v7122934Identification of a New Ribonucleoside Inhibitor of Ebola Virus Replication
resolves10.15252/emmm.202013105A comparative analysis of remdesivir and other repurposed antivirals against SARS‐CoV‐2
resolves10.1002/em.22471Human genetic risk of treatment with antiviral nucleoside analog drugs that induce lethal mutagenesis: the special case of molnupiravir
The 14 references with no DOI or arXiv id, listed, not checked
no DOI — not checkedref1
no DOI — not checked2022a. The SARS-CoV-2 Alpha variant exhibits comparable fitness to the D614G strain in a Syrian hamster model
no DOI — not checkedA robust SARS-CoV-2 replication model in primary human epithelial cells at the air liquid interface to assess antiviral agents
no DOI — not checkedPre-clinical evaluation of antiviral activity of nitazoxanide against SARS-CoV-2
no DOI — not checkedSARS-CoV-2 VOC type and biological sex affect molnupiravir efficacy in severe COVID-19 dwarf hamster model
no DOI — not checkedref23
no DOI — not checkedref24
no DOI — not checkedInhibition of Human Coronavirus NL63 Infection at Early Stages of the Replication Cycle
no DOI — not checkedA molnupiravir-associated mutational signature in global SARS-CoV-2 genomes
no DOI — not checkedAn orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice
no DOI — not checkedCharacterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia
no DOI — not checked2018. ?-D -N 4 -Hydroxycytidine Is a Potent Anti-alphavirus Compound That Induces a High Level of Mutations in the Viral Genome
no DOI — not checkedOrally Efficacious Broad-Spectrum Ribonucleoside Analog Inhibitor of Influenza and Respiratory Syncytial Viruses
no DOI — not checkedIs Also Mutagenic To Mammalian Cells
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