Reference health

Differences in Serum Biomarkers Between Combined Glucosamine and Chondroitin Versus Celecoxib in a Randomized, Double-blind Trial in Osteoarthritis Patients

https://doi.org/10.2174/1871523018666190115094512
CiteStamped reference-health badge
45/45 checkable references clean · checked 2026-07-23

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

9 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 45 checked references that resolve
resolves10.1038/srep10593
Comparison between 200 mg QD and 100 mg BID oral celecoxib in the treatment of knee or hip osteoarthritis
resolves10.1016/j.bpg.2009.11.005
Adverse effects of non-steroidal anti-inflammatory drugs (NSAIDs, aspirin and coxibs) on upper gastrointestinal tract
resolves10.1016/S0140-6736(13)60900-9
Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials
resolves10.1016/j.joca.2007.12.013
OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines
resolves10.1056/NEJMoa052771
Glucosamine, Chondroitin Sulfate, and the Two in Combination for Painful Knee Osteoarthritis
resolves10.1136/annrheumdis-2014-206792
Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
resolves10.1136/ard.2009.120469
Clinical efficacy and safety of glucosamine, chondroitin sulphate, their combination, celecoxib or placebo taken to treat osteoarthritis of the knee: 2-year results from GAIT
resolves10.1016/S1063-4584(03)00028-1
Glucosamine inhibits IL-1β-induced NFκB activation in human osteoarthritic chondrocytes
resolves10.1016/j.canlet.2008.01.022
Chondroitin sulfate extracted from the Styela clava tunic suppresses TNF-α-induced expression of inflammatory factors, VCAM-1 and iNOS by blocking Akt/NF-κB signal in JB6 cells
resolves10.1152/ajpheart.00142.2009
Effect of a high dose of glucosamine on systemic and tissue inflammation in an experimental model of atherosclerosis aggravated by chronic arthritis
resolves10.1007/s00011-007-7020-7
Evaluation of the suppressive actions of glucosamine on the interleukin-1β-mediated activation of synoviocytes
resolves10.1177/153537020523000405
Effects of Chondroitin and Glucosamine Sulfate in a Dietary Bar Formulation on Inflammation, Interleukin-1β, Matrix Metalloprotease-9, and Cartilage Damage in Arthritis
resolves10.1254/jjp.85.155
Effects of Chondroitin Sulfate on Colitis Induced by Dextran Sulfate Sodium in Rats
resolves10.1093/aje/kws186
Association Between Use of Specialty Dietary Supplements and C-Reactive Protein Concentrations
resolves10.1371/journal.pone.0117534
Randomized Trial of Glucosamine and Chondroitin Supplementation on Inflammation and Oxidative Stress Biomarkers and Plasma Proteomics Profiles in Healthy Humans
resolves10.1136/ard.16.4.494
Radiological Assessment of Osteo-Arthrosis
resolves10.1016/j.molonc.2007.08.004
Use of high density antibody arrays to validate and discover cancer serum biomarkers
resolves10.1021/pr4001674
High-Throughput Screening for Native Autoantigen–Autoantibody Complexes Using Antibody Microarrays
resolves10.1074/mcp.M900496-MCP200
Use of a Single-Chain Antibody Library for Ovarian Cancer Biomarker Discovery
resolves10.1158/1078-0432.CCR-13-3474
Cross-Species Antibody Microarray Interrogation Identifies a 3-Protein Panel of Plasma Biomarkers for Early Diagnosis of Pancreas Cancer
resolves10.1016/j.jprot.2013.10.030
Discovery of sialyl Lewis A and Lewis X modified protein cancer biomarkers using high density antibody arrays
resolves10.1007/s10549-012-2204-4
Discovery and preliminary confirmation of novel early detection biomarkers for triple-negative breast cancer using preclinical plasma samples from the Women’s Health Initiative observational study
resolves10.1158/1055-9965.EPI-06-0223
Effect of a 12-Month Exercise Intervention on Patterns of Cellular Proliferation in Colonic Crypts: A Randomized Controlled Trial
resolves10.3233/CBM-2011-0215
Discovery and validation of ovarian cancer biomarkers utilizing high density antibody microarrays
resolves10.1007/0-387-29362-0_23
limma: Linear Models for Microarray Data
resolves10.1016/S1046-2023(03)00155-5
Normalization of cDNA microarray data
resolves10.1016/0049-0172(89)90010-3
Pain assessment in osteoarthritis: Experience with the WOMAC osteoarthritis index
resolves10.1111/j.2517-6161.1995.tb02031.x
Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing
resolves10.1158/1055-9965.EPI-15-0956
Factors Associated with Multiple Biomarkers of Systemic Inflammation
resolves10.1038/nrrheum.2010.196
Role of proinflammatory cytokines in the pathophysiology of osteoarthritis
resolves10.1080/13684730050515796
Interleukin–6 and interleukin–8 levels in serum and synovial fluid of patients with osteoarthritis
resolves10.1038/nrm2125
Matrix metalloproteinases and the regulation of tissue remodelling
resolves10.1074/jbc.M706387200
Interleukin-6 (IL-6) and/or Soluble IL-6 Receptor Down-regulation of Human Type II Collagen Gene Expression in Articular Chondrocytes Requires a Decrease of Sp1·Sp3 Ratio and of the Binding Activity of Both Factors to the COL2A1 Promoter
resolves10.1016/j.joca.2008.06.008
Anti-inflammatory activity of chondroitin sulfate
resolves10.1111/jgh.12485
Effects of dietary supplementation of glucosamine sulfate on intestinal inflammation in a mouse model of experimental colitis
resolves10.1007/s10753-012-9459-0
Suppressive Effects of N-Acetyl-d-Glucosamine on Rheumatoid Arthritis Mouse Models
resolves10.1016/j.niox.2013.02.082
Glucosamine inhibits lipopolysaccharide-stimulated inducible nitric oxide synthase induction by inhibiting expression of NF-kappaB/Rel proteins at the mRNA and protein levels
resolves10.1007/s00296-006-0197-1
Effects of glucosamine administration on patients with rheumatoid arthritis
resolves10.1089/acm.2013.0323
Associations Between Glucosamine and Chondroitin Supplement Use and Biomarkers of Systemic Inflammation
resolves10.1158/1055-9965.EPI-13-0470
Specialty Supplement Use and Biologic Measures of Oxidative Stress and DNA Damage
resolves10.1111/j.1749-6632.2011.06096.x
The growing challenge of obesity and cancer: an inflammatory issue
resolves10.1016/j.coph.2009.06.018
Inflammation, a silent killer in cancer is not so silent!
resolves10.1016/j.ijbiomac.2016.04.091
Structural modulation of gut microbiota by chondroitin sulfate and its oligosaccharide
resolves10.1016/j.ijbiomac.2016.01.055
Degradation of chondroitin sulfate by the gut microbiota of Chinese individuals
resolves10.1093/nar/gkv951
PubChem Substance and Compound databases
The 9 references without a DOI — listed, not checked
no DOI — not checkedYomogida S.; Kojima Y.; Tsutsumi-Ishii Y.; Hua J.; Sakamoto K.; Nagaoka I.; Glucosamine, a naturally occurring amino monosaccharide, suppresses dextran sulfate sodium-induced colitis in rats. Int J Mol Med 2008,22(3),317-323
no DOI — not checkedBellamy N.; Buchanan W.W.; Goldsmith C.H.; Campbell J.; Stitt L.W.; Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol 1988,15(12),1833-1840
no DOI — not checkedChan P.S.; Caron J.P.; Orth M.W.; Short-term gene expression changes in cartilage explants stimulated with interleukin beta plus glucosamine and chondroitin sulfate. J Rheumatol 2006,33(7),1329-1340
no DOI — not checkedYomogida S.; Hua J.; Sakamoto K.; Nagaoka I.; Glucosamine suppresses interleukin-8 production and ICAM-1 expression by TNF-alpha-stimulated human colonic epithelial HT-29 cells. Int J Mol Med 2008,22(2),205-211
no DOI — not checkedNakamura H.; Nishioka K.; Effects of glucosamine/chondroitin supplement on osteoarthritis: involvement of PGE2 and YKL-40. J Rheumatism Joint Surg 2002,21,175-184
no DOI — not checkedMadjid M.; Fatemi O.; Components of the complete blood count as risk predictors for coronary heart disease: in-depth review and update. Tex Heart Inst J 2013,40(1),17-29
no DOI — not checkedNational Center for Biotechnology InformationPub- Chem Compound Database; Glucosamine Hydrochloride; CID=91431; https://pubchem.ncbi.nlm.nih.gov/ compound/45933886 (accessed Dec 17, 2018).
no DOI — not checkedNational Center for Biotechnology Information Pub- Chem Compound Database; Chondroitin Sulfate; CID=24766; https://pubchem.ncbi.nlm.nih.gov/com pound/24766 (accessed Dec 17, 2018).
no DOI — not checkedNational Center for Biotechnology InformationPub- Chem Compound Database; Celecoxib; CID=2662, https://pubchem.ncbi.nlm.nih.gov/compound/2662 (accessed Dec 17, 2018).
What this badge says. CiteStamped means the CHECKABLE references of this work were clean at the dated check: each resolved to a known work in a public registry, and none carried a retraction notice at that time. It says nothing about the quality, findings, or importance of the work itself, and nothing about references deposited without a DOI.

checked 2026-07-23 — re-checked daily as this page is visited; titles and statuses come from Crossref and DataCite and are not part of the signed record

Embed this badge

Both snippets point at the live badge image and link back to this page. The badge re-renders from the daily check, so an embed never goes stale by more than a day of visits.

<a href="https://citestamp.com/citestamped/10.2174/1871523018666190115094512"><img src="https://citestamp.com/citestamped/10.2174/1871523018666190115094512/badge.svg" alt="CiteStamped reference-health badge" width="460" height="64"></a>
[![CiteStamped reference-health badge](https://citestamp.com/citestamped/10.2174/1871523018666190115094512/badge.svg)](https://citestamp.com/citestamped/10.2174/1871523018666190115094512)