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Toxicological Effects of Berberine and Sanguinarine

https://doi.org/10.3389/fmolb.2018.00021
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1 of 48 checkable references need attention · checked 2026-07-23

At the dated check, the references listed below either did not resolve in Crossref or DataCite, or carried a retraction notice. Each one is shown with the registry record that put it there.

5 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

References needing attention

does not resolve to a known work10.1254/jjp.22.11
The 47 checked references that resolve
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In vitro biological assessment of berberis vulgaris and its active constituent, berberine: antioxidants, anti-acetylcholinesterase, anti-diabetic and anticancer effects
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Berberis and Mahonia.
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Hormetic Effect of Berberine Attenuates the Anticancer Activity of Chemotherapeutic Agents
resolves10.1080/15287398709530972
Short‐term toxicity studies of Sanguinarine and of two alkaloid extracts of<i>Sanguinaria Canadensis</i>L.
resolves10.1590/S0102-695X2013005000021
Argemone mexicana: Chemical and pharmacological aspects
resolves10.7314/APJCP.2014.15.21.9445
Promoting Effects of Sanguinarine on Apoptotic Gene Expression in Human Neuroblastoma Cells
resolves10.1186/1472-6882-2-2
Potential antimutagenic activity of berberine, a constituent of Mahonia aquifolium
resolves10.1016/j.toxlet.2011.06.018
Embryonic toxicity of sanguinarine through apoptotic processes in mouse blastocysts
resolves10.1515/znc-2003-7-813
Cytotoxic Benzophenanthridine and Benzylisoquinoline Alkaloids from Argemone mexicana
resolves10.3390/ijms14022928
Antioxidant, Analgesic, Anti-Inflammatory, and Hepatoprotective Effects of the Ethanol Extract of Mahonia oiwakensis Stem
resolves10.1002/jat.1360
Induction of hepatotoxicity by sanguinarine is associated with oxidation of protein thiols and disturbance of mitochondrial respiration
resolves10.1007/BF02005884
Sanguinarine: its potential, as a liver toxic alkaloid present in the seeds ofArgemone mexicana
resolves10.1111/j.1600-051X.1994.tb00786.x
Antioxidative activities of some chemotherapeutics. A possible mechanism in reducing gingival inflammation
resolves10.4251/wjgo.v8.i1.30
Antitumor effects of the benzophenanthridine alkaloid sanguinarine: Evidence and perspectives
resolves10.1039/c3ay41494a
Application of electrospray ionization mass spectrometry for the evaluation of alkaloids binding to G-quadruplex of HIV-1 integrase inhibitors
resolves10.1155/2014/871720
From Prejudice to Evidence: The Case of Rhizoma Coptidis in Singapore
resolves10.1016/B978-008045046-9.01737-X
Brain Na,K-ATPase
resolves10.1002/ptr.2399
Pharmacological and therapeutic effects of<i>Berberis vulgaris</i>and its active constituent, berberine
resolves10.1100/2012/823201
Molecular Basis of Inhibitory Activities of Berberine against Pathogenic Enzymes in Alzheimer's Disease
resolves10.1016/S0024-3205(02)02200-2
A comparative study on the anti-inflammatory, antinociceptive and antipyretic effects of isoquinoline alkaloids from the roots of Turkish Berberis species
resolves10.1016/j.neulet.2010.09.038
Effects of berberine on 6-hydroxydopamine-induced neurotoxicity in PC12 cells and a rat model of Parkinson's disease
resolves10.1002/ncr.4100810215
Waste watch
resolves10.1038/cr.2009.76
Berberine promotes the development of atherosclerosis and foam cell formation by inducing scavenger receptor A expression in macrophage
resolves10.1007/s10753-013-9640-0
Berberine Attenuates Cigarette Smoke-Induced Acute Lung Inflammation
resolves10.1111/j.1742-4658.2006.05227.x
The benzophenanthridine alkaloid sanguinarine perturbs microtubule assembly dynamics through tubulin binding
resolves10.3109/1547691X.2015.1058306
Immunotoxicity induced in mice by subacute exposure to berberine
resolves10.5507/bp.2006.001
EFFECTS OF SANGUINARINE AND CHELERYTHRINE ON THE CELL CYCLE AND APOPTOSIS
resolves10.1007/s10565-006-0109-x
The effect of chelerythrine on cell growth, apoptosis, and cell cycle in human normal and cancer cells in comparison with sanguinarine
resolves10.1016/j.cbi.2007.12.006
Sanguinarine causes DNA damage and p53-independent cell death in human colon cancer cell lines
resolves10.1016/j.etap.2014.11.006
Pharmacological and safety evaluation of fibrous root of Rhizoma Coptidis
resolves10.1016/j.bbrc.2010.07.114
Sanguinarine induces apoptosis of human osteosarcoma cells through the extrinsic and intrinsic pathways
resolves10.1007/BF00987648
Berberine: A naturally occurring phototoxic alkaloid
resolves10.1016/j.chroma.2008.03.039
Separation of sanguinarine and chelerythrine in Macleaya cordata (Willd) R. Br. based on methyl acrylate-co-divinylbenzene macroporous adsorbents
resolves10.21273/HORTSCI.45.7.1029
Ploidy Levels and Genome Sizes of Berberis L. and Mahonia Nutt. Species, Hybrids, and Cultivars
resolves10.1023/A:1010907231602
Interaction of benzo[c]phenanthridine and protoberberine alkaloids with animal and yeast cells
resolves10.1016/j.tiv.2010.01.012
Effect of quaternary benzo[c]phenanthridine alkaloids sanguilutine and chelilutine on normal and cancer cells
resolves10.2147/IJN.S22683
Berberine hydrochloride: anticancer activity and nanoparticulate delivery system
resolves10.1093/ecam/nep111
Cytotoxic Effects of Bangladeshi Medicinal Plant Extracts
resolves10.1016/S0379-0738(00)00322-4
Argemone mexicana poisoning: autopsy findings of two cases
resolves10.1074/jbc.M109.088989
Structure and Mechanism of Sanguinarine Reductase, an Enzyme of Alkaloid Detoxification
resolves10.1016/j.tiv.2009.01.016
Cytotoxic activity of sanguinarine and dihydrosanguinarine in human promyelocytic leukemia HL-60 cells
resolves10.1006/exmp.2001.2355
Bax, Bcl-2, and NF-κB Expression in Sanguinarine Induced Bimodal Cell Death
resolves10.1023/A:1013796432521
Role of Bcl-2 family proteins and caspase-3 in sanguinarine-induced bimodal cell death
resolves10.2174/1872213X12666180115153635
Anti-Inflammatory Drugs and Herbs with Special Emphasis on Herbal Medicines for Countering Inflammatory Diseases and Disorders - A Review
resolves10.1016/S0378-8741(01)00387-7
Berberis crataegina DC. root exhibits potent anti-inflammatory, analgesic and febrifuge effects in mice and rats
resolves10.1016/j.apsb.2012.06.003
Effects and mechanisms of berberine in diabetes treatment
resolves10.1248/bpb.31.1169
Chronic Effects of Berberine on Blood, Liver Glucolipid Metabolism and Liver PPARs Expression in Diabetic Hyperlipidemic Rats
The 5 references without a DOI — listed, not checked
no DOI — not checkedDifferential antiproliferative and apoptotic response of sanguinarine for cancer cells versus normal cells
no DOI — not checkedBerberine: production through plant (Thalictrum spp.) cell cultures
no DOI — not checkedNew perspectives on sanguinaria clinicals: individual toothpaste and oral rise testing
no DOI — not checkedThe Alkaliods: Chemistry and Physiology
no DOI — not checkedBerberine inhibits WEHI-3 leukemia cells in vivo
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