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Icariin, an Anti-atherosclerotic Drug from Chinese Medicinal Herb Horny Goat Weed

https://doi.org/10.3389/fphar.2017.00734
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1 of 45 checkable references need attention · checked 2026-07-22

At the dated check, the references listed below either did not resolve in Crossref or DataCite, or carried a retraction notice. Each one is shown with the registry record that put it there.

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References needing attention

does not resolve to a known work10.3760/cma.j.issn.0253-3758.2016.08.013
The 44 checked references that resolve
resolves10.3389/fphar.2015.00237
Natural products and drug discovery: a survey of stakeholders in industry and academia
resolves10.1161/CIR.0000000000000485
Heart Disease and Stroke Statistics—2017 Update: A Report From the American Heart Association
resolves10.1248/bpb.33.1307
Icariin Derivative Inhibits Inflammation through Suppression of p38 Mitogen-Activated Protein Kinase and Nuclear Factor-.KAPPA.B Pathways
resolves10.1155/2015/895976
Icariin Intervenes in Cardiac Inflammaging through Upregulation of SIRT6 Enzyme Activity and Inhibition of the NF-Kappa B Pathway
resolves10.1016/j.bbrc.2008.09.001
Icariin stimulates angiogenesis by activating the MEK/ERK- and PI3K/Akt/eNOS-dependent signal pathways in human endothelial cells
resolves10.1002/med.21438
Atheroprotective Effects and Molecular Targets of Tanshinones Derived From Herbal Medicine Danshen
resolves10.1161/CIRCRESAHA.115.306301
Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis
resolves10.1016/S1875-5364(16)30079-6
Epimedium koreanum Nakai and its main constituent icariin suppress lipid accumulation during adipocyte differentiation of 3T3-L1 preadipocytes
resolves10.1007/s10753-015-0242-x
Icariin Attenuates High-cholesterol Diet Induced Atherosclerosis in Rats by Inhibition of Inflammatory Response and p38 MAPK Signaling Pathway
resolves10.3892/mmr.2016.4813
Icariin inhibits oxidized low-density lipoprotein-induced proliferation of vascular smooth muscle cells by suppressing activation of extracellular signal-regulated kinase 1/2 and expression of proliferating cell nuclear antigen
resolves10.1016/j.febslet.2010.04.049
Involvement of androgen receptor in nitric oxide production induced by icariin in human umbilical vein endothelial cells
resolves10.1038/nature10146
Progress and challenges in translating the biology of atherosclerosis
resolves10.1016/j.trsl.2016.02.005
Deletion of sirtuin 6 accelerates endothelial dysfunction and atherosclerosis in apolipoprotein E-deficient mice
resolves10.1111/bph.13068
Cryptotanshinone, an orally bioactive herbal compound from <scp>D</scp>anshen, attenuates atherosclerosis in apolipoprotein <scp>E</scp>‐deficient mice: role of lectin‐like oxidized LDL receptor‐1 (<scp>LOX</scp>‐1)
resolves10.1211/0022357044869
The antioxidative effect of icariin in human erythrocytes against free-radical-induced haemolysis
resolves10.1155/2015/463797
Development of Antiatherosclerotic Drugs on the basis of Natural Products Using Cell Model Approach
resolves10.1161/CIRCRESAHA.115.306297
The Success Story of LDL Cholesterol Lowering
resolves10.1038/nature06796
Translating molecular discoveries into new therapies for atherosclerosis
resolves10.1016/S0021-9150(03)00239-9
Statins in atherosclerosis: lipid-lowering agents with antioxidant capabilities
resolves10.1038/362801a0
The pathogenesis of atherosclerosis: a perspective for the 1990s
resolves10.1016/j.cell.2015.11.031
A New Golden Age of Natural Products Drug Discovery
resolves10.1111/bph.13631
Anti‐ageing active ingredients from herbs and nutraceuticals used in traditional Chinese medicine: pharmacological mechanisms and implications for drug discovery
resolves10.1083/jcb.201412052
Recent insights into the cellular biology of atherosclerosis
resolves10.1016/j.bbrc.2016.01.118
Icariin inhibits atherosclerosis progress in Apoe null mice by downregulating CX3CR1 in macrophage
resolves10.1016/j.phrs.2005.02.023
Protective effects of icariin on human umbilical vein endothelial cell injury induced by H2O2 in vitro
resolves10.1016/j.fct.2013.12.006
Icaritin attenuates cigarette smoke-mediated oxidative stress in human lung epithelial cells via activation of PI3K-AKT and Nrf2 signaling
resolves10.1016/j.mce.2009.11.003
Regulated expression of endothelial lipase in atherosclerosis
resolves10.1016/j.pharep.2015.04.017
Icariin regulates PRMT/ADMA/DDAH pathway to improve endothelial function
resolves10.1139/cjpp-2016-0367
Icariin improves eNOS/NO pathway to prohibit the atherogenesis of apolipoprotein E-null mice
resolves10.3109/13880209.2012.738332
Icariin delays homocysteine-induced endothelial cellular senescence involving activation of the PI3K/AKT-eNOS signaling pathway
resolves10.1016/j.ejphar.2010.05.012
Icariin attenuates LPS-induced acute inflammatory responses: Involvement of PI3K/Akt and NF-κB signaling pathway
resolves10.1016/j.vph.2007.03.002
Icariin enhances endothelial nitric-oxide synthase expression on human endothelial cells in vitro
resolves10.3389/fphar.2017.00563
Transcriptome Profiling in Systems Vascular Medicine
resolves10.1016/j.tem.2016.07.004
Sirtuins in Cardiovascular Health and Diseases
resolves10.18632/oncotarget.9376
A novel TRPV4-specific agonist inhibits monocyte adhesion and atherosclerosis
resolves10.18632/aging.100975
SIRT6 protects against endothelial dysfunction and atherosclerosis in mice
resolves10.1002/med.21300
Poly(ADP‐ribose) Polymerase 1 (PARP1) in Atherosclerosis: From Molecular Mechanisms to Therapeutic Implications
resolves10.1016/j.ijcard.2014.01.068
Targeting hydrogen sulfide as a promising therapeutic strategy for atherosclerosis
resolves10.1007/s00018-012-1194-z
LOX-1 in atherosclerosis: biological functions and pharmacological modifiers
resolves10.1002/jcb.25009
Icariin Inhibits Foam Cell Formation by Down‐Regulating the Expression of CD36 and Up‐Regulating the Expression of SR‐BI
resolves10.1016/j.exger.2015.06.020
Icariin, a natural flavonol glycoside, extends healthspan in mice
resolves10.1055/s-0032-1328551
Icariin Attenuates the Enhanced Prothrombotic State in Atherosclerotic Rabbits Independently of Its Lipid-Lowering Effects
resolves10.1038/srep23912
Epigenetic regulation of NKG2D ligands is involved in exacerbated atherosclerosis development in Sirt6 heterozygous mice
resolves10.1211/jpp.59.12.0016
Protective effect of <i>icariin</i> on DNA against radical-induced oxidative damage
The 6 references without a DOI — listed, not checked
no DOI — not checkedImmunoregulatory effects of the herba Epimedium glycoside icariin.
no DOI — not checkedEffects and mechanisms of icariin on atherosclerosis.
no DOI — not checked[Effects of icariin and icariside II on eNOS expression and NOS activity in porcine aorta endothelial cells].
no DOI — not checked[Effects of icariin on expression of glucose regulated protein 78 in vascular smooth muscle cell induced by homocysteine].
no DOI — not checkedEffects of icariin on cGMP-specific PDE5 and cAMP-specific PDE4 activities.
no DOI — not checked[Advances in study on pharmacological effects of Epimedium].
What this badge says. CiteStamped means the CHECKABLE references of this work were clean at the dated check: each resolved to a known work in a public registry, and none carried a retraction notice at that time. It says nothing about the quality, findings, or importance of the work itself, and nothing about references deposited without a DOI.

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