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Hyaluronic Acid-Based Theranostic Nanomedicines for Targeted Cancer Therapy
1 of 104 checkable references need attention · checked 2026-07-23
At the dated check, the references listed below either did not resolve in Crossref or DataCite, or carried a retraction notice. Each one is shown with the registry record that put it there.
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References needing attention
marked retracted — notice via Crossref, record curated by Retraction Watch10.1039/C9NR01691K
Enhanced anti-tumor efficacy of hyaluronic acid modified nanocomposites combined with sonochemotherapy against subcutaneous and metastatic breast tumors
The 103 checked references that resolve
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Nanomedicines for cancer therapy: state-of-the-art and limitations to pre-clinical studies that hinder future developments
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Nanodelivery Strategies in Cancer Chemotherapy: Biological Rationale and Pharmaceutical Perspectives
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Hyaluronan, a truly “youthful” polysaccharide. Its medical applications
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Expression of the cell adhesion molecule CD44 in human lung tumors and cell lines*
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CD44: a validated target for improved delivery of cancer therapeutics
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Hyaluronan Regulates Cell Behavior: A Potential Niche Matrix for Stem Cells
resolves10.1002/j.1460-2075.1994.tb06261.x
Identification of a common hyaluronan binding motif in the hyaluronan binding proteins RHAMM, CD44 and link protein.
resolves10.1158/2159-8290.CD-11-0136
Targeting the Tumor Microenvironment in Cancer: Why Hyaluronidase Deserves a Second Look
resolves10.1186/1471-2407-12-458
Overexpression of CD44 accompanies acquired tamoxifen resistance in MCF7 cells and augments their sensitivity to the stromal factors, heregulin and hyaluronan
resolves10.4161/cib.4.2.14270
How does a protein with dual mitotic spindle and extracellular matrix receptor functions affect tumor susceptibility and progression?
resolves10.1593/neo.09694
RHAMM (CD168) Is Overexpressed at the Protein Level and May Constitute an Immunogenic Antigen in Advanced Prostate Cancer Disease
resolves10.1016/j.jconrel.2014.10.024
Stealth CD44-targeted hyaluronic acid supramolecular nanoassemblies for doxorubicin delivery: Probing the effect of uncovalent pegylation degree on cellular uptake and blood long circulation
resolves10.1111/j.1742-4658.2011.08071.x
Hyaluronan–CD44 interactions as potential targets for cancer therapy
resolves10.1016/j.carbpol.2011.03.019
Chemical modifications of hyaluronic acid for the synthesis of derivatives for a broad range of biomedical applications
resolves10.1016/j.carbpol.2012.10.028
Hyaluronic acid based scaffolds for tissue engineering—A review
resolves10.3390/molecules19033193
Hyaluronic Acid Conjugates as Vectors for the Active Targeting of Drugs, Genes and Nanocomposites in Cancer Treatment
resolves10.3109/1061186X.2015.1052072
Hyaluronic acid targeting of CD44 for cancer therapy: from receptor biology to nanomedicine
resolves10.1039/C9TB01115C
Light-activated drug release from a hyaluronic acid targeted nanoconjugate for cancer therapy
resolves10.1016/j.nucmedbio.2009.02.005
Biodistribution imaging of a paclitaxel-hyaluronan bioconjugate
resolves10.1007/s11095-009-9997-9
The Use of Amino Acid Linkers in the Conjugation of Paclitaxel with Hyaluronic Acid as Drug Delivery System: Synthesis, Self-Assembled Property, Drug Release, and In Vitro Efficiency
resolves10.1158/1535-7163.MCT-13-0132
Paclitaxel–Hyaluronic NanoConjugates Prolong Overall Survival in a Preclinical Brain Metastases of Breast Cancer Model
resolves10.1016/j.biomaterials.2016.01.049
Hyaluronic acid-shelled acid-activatable paclitaxel prodrug micelles effectively target and treat CD44-overexpressing human breast tumor xenografts in vivo
resolves10.1002/mabi.201300383
Tailored Doxorubicin‐<scp>H</scp>yaluronan Conjugate as a Potent Anticancer Glyco‐<scp>D</scp>rug: An Alternative to Prodrug Approach
resolves10.1016/j.jconrel.2010.04.006
Localized doxorubicin chemotherapy with a biopolymeric nanocarrier improves survival and reduces toxicity in xenografts of human breast cancer
resolves10.1007/s13233-012-0062-x
Gold half-shell coated hyaluronic acid-doxorubicin conjugate micelles for theranostic applications
resolves10.1016/j.ijpharm.2010.03.058
Pulmonary delivery of cisplatin–hyaluronan conjugates via endotracheal instillation for the treatment of lung cancer
resolves10.1001/jamaoto.2013.214
Efficacy and Toxicity of Peritumoral Delivery of Nanoconjugated Cisplatin in an In Vivo Murine Model of Head and Neck Squamous Cell Carcinoma
resolves10.1021/bc100354m
Hyaluronic Acid Immobilized Magnetic Nanoparticles for Active Targeting and Imaging of Macrophages
resolves10.1016/j.biomaterials.2014.02.006
Hyaluronic acid-chitosan nanoparticles for co-delivery of MiR-34a and doxorubicin in therapy against triple negative breast cancer
resolves10.1039/C2NR32145A
Hyaluronic acid modified mesoporous silica nanoparticles for targeted drug delivery to CD44-overexpressing cancer cells
resolves10.1126/science.8134834
Functional Polymers and Dendrimers: Reactivity, Molecular Architecture, and Interfacial Energy
resolves10.1016/j.colsurfb.2015.09.043
Hyaluronic acid-conjugated polyamidoamine dendrimers for targeted delivery of 3,4-difluorobenzylidene curcumin to CD44 overexpressing pancreatic cancer cells
resolves10.1016/j.jconrel.2004.11.017
Polymeric micellar pH-sensitive drug delivery system for doxorubicin
resolves10.1016/j.biomaterials.2009.04.002
Mixed micelle systems formed from critical micelle concentration and temperature-sensitive diblock copolymers for doxorubicin delivery
resolves10.1016/j.biomaterials.2013.02.067
Ultrasound-sensitive siRNA-loaded nanobubbles formed by hetero-assembly of polymeric micelles and liposomes and their therapeutic effect in gliomas
resolves10.1002/mabi.200800229
Poly[lactic‐<i>co</i>‐(glycolic acid)]‐Grafted Hyaluronic Acid Copolymer Micelle Nanoparticles for Target‐Specific Delivery of Doxorubicin
resolves10.1016/j.biomaterials.2011.11.022
Redox-sensitive micelles self-assembled from amphiphilic hyaluronic acid-deoxycholic acid conjugates for targeted intracellular delivery of paclitaxel
resolves10.1016/j.actbio.2013.12.025
Self-assembled pH-responsive hyaluronic acid–g-poly(l-histidine) copolymer micelles for targeted intracellular delivery of doxorubicin
resolves10.1248/yakushi.128.269
Lipid Carriers: A Versatile Delivery Vehicle for Proteins and Peptides
resolves10.1007/s11095-016-1958-5
Nanoparticle-Based Medicines: A Review of FDA-Approved Materials and Clinical Trials to Date
resolves10.1089/oli.2008.0168
Hyaluronic Acid-Modified DOTAP/DOPE Liposomes for the Targeted Delivery of Anti-Telomerase siRNA to CD44-Expressing Lung Cancer Cells
resolves10.1016/j.biomaterials.2012.09.027
Dual-functional liposomes based on pH-responsive cell-penetrating peptide and hyaluronic acid for tumor-targeted anticancer drug delivery
resolves10.1517/17425240902932908
Multifunctional nanoparticles for imaging, delivery and targeting in cancer therapy
resolves10.1021/ar200044b
Surface-Engineered Magnetic Nanoparticle Platforms for Cancer Imaging and Therapy
resolves10.1016/j.jcis.2015.11.001
Polydopamine-based surface modification of mesoporous silica nanoparticles as pH-sensitive drug delivery vehicles for cancer therapy
resolves10.1021/jp072958n
Self-Assembly of Gold Nanoparticles at the Surface of Amine- and Thiol-Functionalized Boron Nitride Nanotubes
resolves10.1016/j.ab.2005.04.040
Direct electrochemistry and electrocatalysis of heme proteins immobilized on gold nanoparticles stabilized by chitosan
resolves10.4172/2161-0525.1000384
Gold and Silver Nanoparticles: Synthesis Methods, Characterization Routes and Applications towards Drugs
resolves10.1021/nl200636r
Controlling in Vivo Stability and Biodistribution in Electrostatically Assembled Nanoparticles for Systemic Delivery
resolves10.1016/j.jconrel.2009.09.010
Target specific and long-acting delivery of protein, peptide, and nucleotide therapeutics using hyaluronic acid derivatives
resolves10.1016/j.jconrel.2006.03.013
Hyaluronic acid and its derivative as a multi-functional gene expression enhancer: Protection from non-specific interactions, adhesion to targeted cells, and transcriptional activation
resolves10.1007/s13233-015-3061-x
Hybrid photoactive nanomaterial composed of gold nanoparticles, pheophorbide-A and hyaluronic acid as a targeted bimodal phototherapy
resolves10.1021/nn302538y
Hyaluronic Acid–Gold Nanoparticle/Interferon α Complex for Targeted Treatment of Hepatitis C Virus Infection
resolves10.1016/j.addr.2008.03.015
Bioconjugated quantum dots for in vivo molecular and cellular imaging☆
resolves10.1021/ja042939g
Synthesis and Characterization of Highly Luminescent CdSe−Core CdS/Zn<sub>0.5</sub>Cd<sub>0.5</sub>S/ZnS Multishell Nanocrystals
resolves10.1007/s11051-014-2621-x
Biocompatible hyaluronic acid polymer-coated quantum dots for CD44+ cancer cell-targeted imaging
resolves10.7150/thno.17411
Hyaluronic Acid Conjugated Magnetic Prussian Blue@Quantum Dot Nanoparticles for Cancer Theranostics
resolves10.1016/j.biomaterials.2010.01.057
Dual drug loaded superparamagnetic iron oxide nanoparticles for targeted cancer therapy
resolves10.1016/j.biomaterials.2014.01.011
Hyaluronic acid-modified hydrothermally synthesized iron oxide nanoparticles for targeted tumor MR imaging
resolves10.1517/17425247.5.3.331
Opportunities and challenges of carbon-based nanomaterials for cancer therapy
resolves10.1016/j.biomaterials.2013.08.058
Cholesteryl hyaluronic acid-coated, reduced graphene oxide nanosheets for anti-cancer drug delivery
resolves10.1016/j.carbpol.2018.07.066
Hyaluronic acid functionalized green reduced graphene oxide for targeted cancer photothermal therapy
resolves10.1007/s11051-017-3977-5
In vitro and in vivo comparative study of the phototherapy anticancer activity of hyaluronic acid-modified single-walled carbon nanotubes, graphene oxide, and fullerene
resolves10.1021/bm101446k
Diels−Alder Click Cross-Linked Hyaluronic Acid Hydrogels for Tissue Engineering
resolves10.1039/b719557e
An injectable enzymatically crosslinked hyaluronic acid–tyramine hydrogel system with independent tuning of mechanical strength and gelation rate
resolves10.1016/j.jconrel.2008.11.028
An injectable hyaluronic acid–tyramine hydrogel system for protein delivery
resolves10.1016/j.jconrel.2013.01.008
Injectable hyaluronic acid-tyramine hydrogels incorporating interferon-α2a for liver cancer therapy
resolves10.1016/j.biomaterials.2014.10.039
Intraperitoneal delivery of platinum with in-situ crosslinkable hyaluronic acid gel for local therapy of ovarian cancer
resolves10.1021/acs.biomac.7b00788
Thiol-Mediated Synthesis of Hyaluronic Acid–Epigallocatechin-3-<i>O</i>-Gallate Conjugates for the Formation of Injectable Hydrogels with Free Radical Scavenging Property and Degradation Resistance
resolves10.1039/b919944f
Thermo-sensitive, injectable, and tissue adhesive sol–gel transition hyaluronic acid/pluronic composite hydrogels prepared from bio-inspired catechol-thiol reaction
resolves10.2217/nnm.14.211
Novel Injectable Thermosensitive Hydrogels for Delivering Hyaluronic Acid–Doxorubicin Nanocomplexes to Locally Treat Tumors
resolves10.1016/j.colsurfb.2015.12.013
Rheological behavior and Ibuprofen delivery applications of pH responsive composite alginate hydrogels
resolves10.1021/acs.analchem.7b05015
A pH-Sensing Optode for Mapping Spatiotemporal Gradients in 3D Paper-Based Cell Cultures
resolves10.1016/j.polymer.2016.11.063
Self-healing pH-sensitive cytosine- and guanosine-modified hyaluronic acid hydrogels via hydrogen bonding
resolves10.1039/C5NR01075F
A hyaluronic acid nanogel for photo–chemo theranostics of lung cancer with simultaneous light-responsive controlled release of doxorubicin
resolves10.1016/j.carbpol.2015.04.024
Conjugating an anticancer drug onto thiolated hyaluronic acid by acid liable hydrazone linkage for its gelation and dual stimuli-response release
The 5 references without a DOI — listed, not checked
no DOI — not checkedStewart, B., and Wild, C. (2014). World Cancer Report 2014, World Health Organization. Report, International Agency for Research on Cancer.
no DOI — not checkedEnrichment of CD44 in basal-type breast cancer correlates with EMT, cancer stem cell gene profile, and prognosis
no DOI — not checkedExpression of CD44 in human lung tumors
no DOI — not checkedHYTAD1-p20: A new paclitaxel-hyaluronic acid hydrosoluble bioconjugate for treatment of superficial bladder cancer
no DOI — not checkedHyaluronic acid-modified manganese-chelated dendrimer-entrapped gold nanoparticles for the targeted CT/MR dual-mode imaging of hepatocellular carcinoma
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